Experimental structures of coordination spheres of Fluorine (F) in bioorganic molecules from X-Ray and NMR experiments. Coordination spheres were calculated with 5.0 Angstroms radius around Fluorine atoms.
PDB files 1451-1500 (3i8d - 3jx1):- 3i8d - The Pairing Geometry of the Hydrophobic Thymine Analog 2,4- Difluorotoluene in Duplex Dna As Analyzed By X-Ray Crystallography
- 3i9j - Crystal Structure of Adp Ribosyl Cyclase Complexed With A Substrate Analog and A Product Nicotinamide
- 3i9m - Crystal Structure of Human CD38 Complexed With An Analog Ara-2'F-Adpr
- 3i9n - Crystal Structure of Human CD38 Complexed With An Analog Ribo-2'F-Adp Ribose
- 3i9o - Crystal Structure of Adp Ribosyl Cyclase Complexed With Ribo-2'F-Adp Ribose
- 3iad - Crystal Structure of Human Phosphodiesterase 4D With Bound Allosteric Modulator
- 3ice - Rho Transcription Termination Factor Bound to Rna and Adp- BEF3
- 3icn - Trypanosoma Cruzi Farnesyl Diphosphate Synthase Homodimer in Complex With Isopentenyl Pyrophosphate and 3-Fluoro-1-(2- Hydroxy-2,2-Bis-Phosphono-Ethyl)-Pyridinium
- 3id0 - Trypanosoma Cruzi Farnesyl Diphosphate Synthase Homodimer in Complex With 3-Fluoro-1-(2-Hydroxy-2,2-Bisphosphono-Ethyl) Pyridinium
- 3id8 - Ternary Complex of Human Pancreatic Glucokinase Crystallized With Activator, Glucose and Amp-Pnp
- 3ies - Firefly Luciferase Inhibitor Complex
- 3ig6 - Low Molecular Weigth Human Urokinase Type Plasminogen Activator 2-[6- (3'-Aminomethyl-Biphenyl-3-Yloxy)-4-(3-Dimethylamino-Pyrrolidin-1- Yl)-3,5-Difluoro-Pyridin-2-Yloxy]-4-Dimethylamino-Benzoic Acid Complex
- 3igu - Crystal Structure of Human Alpha-N-Acetylgalactosaminidase, Covalent Intermediate
- 3igv - Crystal Structure of Hcv NS5B Polymerase With A Novel Monocyclic Dihydro-Pyridinone Inhibitor
- 3ii5 - The Complex of Wild-Type B-Raf With Pyrazolo Pyrimidine Inhibitor
- 3ij7 - Directed 'in Situ' Elongation As A Strategy to Characterize the Covalent Glycosyl-Enzyme Catalytic Intermediate of Human Pancreatic A-Amylase
- 3ij8 - Directed 'in Situ' Elongation As A Strategy to Characterize the Covalent Glycosyl-Enzyme Catalytic Intermediate of Human Pancreatic A-Amylase
- 3ij9 - Directed 'in Situ' Elongation As A Strategy to Characterize the Covalent Glycosyl-Enzyme Catalytic Intermediate of Human Pancreatic A-Amylase
- 3ik3 - AP24534, A Pan-Bcr-Abl Inhibitor For Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance
- 3ilu - Crystal Structure of The Ampa Subunit GLUR2 Bound to the Allosteric Modulator, Hydroflumethiazide
- 3inh - BACE1 With the Aminohydantoin Compound R-58
- 3iok - 2-Aminopyrazolo[1,5-A]Pyrimidines As Potent and Selective Inhibitors of JAK2
- 3ipn - Crystal Structure of Fluorine and Methyl Modified Collagen: (Mepflpgly)7
- 3ipq - X-Ray Structure of GW3965 Synthetic Agonist Bound to the Lxr-Alpha
- 3ips - X-Ray Structure of Benzisoxazole Synthetic Agonist Bound to the Lxr- Alpha
- 3ipu - X-Ray Structure of Benzisoxazole Urea Synthetic Agonist Bound to the Lxr-Alpha
- 3ipx - X-Ray Structure of Human Deoxycytidine Kinase in Complex With Adp and An Inhibitor
- 3iro - Trypanosoma Cruzi Dihydrofolate Reductase-Thymidylate Synthase Complexed With Nadph and Q-8 Antifolate
- 3itz - Crystal Structure of P38A Mitogen-Activated Protein Kinase in Complex With A Pyrazolopyridazine Inhibitor
- 3iu8 - M. Tuberculosis Methionine Aminopeptidase With Ni Inhibitor T03
- 3ivh - Design and Synthesis Of Potent Bace-1 Inhibitors With Cellular Activity: Structure-Activity Relationship of P1 Substituents
- 3ivi - Design and Synthesis Of Potent Bace-1 Inhibitors With Cellular Activity: Structure-Activity Relationship of P1 Substituents
- 3iw5 - Human P38 Map Kinase in Complex With An Indole Derivative
- 3iw8 - Structure of Inactive Human P38 Map Kinase in Complex With A Thiazole-Urea
- 3ixj - Crystal Structure of Beta-Secretase 1 in Complex With Selective Beta-Secretase 1 Inhibitor
- 3ixk - Potent Beta-Secretase 1 Inhibitor
- 3jps - Ternary Complex of Dna Polymerase Beta With A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma-Fluoro Methyl Methylene Triphosphate
- 3jpt - Ternary Complex of Dna Polymerase Beta With A Dideoxy Terminated Primer and 2'-Deoxyguanosine 5'-Beta, Gamma-Fluoro Chloro Methylene Triphosphate
- 3jsf - Crystal Structure of Macrophage Migration Inhibitory Factor (Mif) With Hydroxyquinoline Inhibitor 638 At 1.93A Resolution
- 3jwe - Crystal Structure of Human Mono-Glyceride Lipase in Complex With SAR629
- 3jws - Structure of Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain Complexed With N1-[(3' S,4'S)-4'-((6"-Amino-4"-Methylpyridin-2"-Yl) Methyl)Pyrrolidin-3'-Yl]-N2-(3'-Fluorophenethyl)Ethane-1,2-Diamine Tetrahydrochloride
- 3jwt - Structure of Rat Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex With N1-{(3'R,4'R)-4'-[(6"-Amino-4"-Methylpyridin- 2"-Yl)Methyl]Pyrrolidin-3'-Yl}-N2-(3'-Fluorophenethyl)Ethane-1,2- Diamine
- 3jwu - Structure of Rat Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex With N1-{(3'R,4'S)-4'-[(6"-Amino-4"-Methylpyridin- 2"-Yl)Methyl]Pyrrolidin-3'-Yl}-N2-(3'-Fluorophenethyl)Ethane-1,2- Diamine Tetrahydrochloride
- 3jwv - Structure of Rat Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex With N1-{(3'S,4'R)-4'-[(6"-Amino-4"-Methylpyridin- 2"-Yl)Methyl]Pyrrolidin-3'-Yl}-N2-(3'-Fluorophenethyl)Ethane-1,2- Diamine
- 3jww - Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed With N1-[(3'S,4'S)-4'-((6"-Amino-4"-Methylpyridin-2"-Yl)Methyl) Pyrrolidin-3'-Yl]-N2- (3'-Fluorophenethyl)Ethane-1,2-Diamine Tetrahydrochloride
- 3jwx - Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed With N1-[(3'R,4'R)-4'-((6"-Amino-4"-Methylpyridin-2"-Yl)Methyl) Pyrrolidin-3'-Yl]-N2-(3'-Fluorophenethyl)Ethane-1,2-Diamine Tetrahydrochloride
- 3jwy - Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed With N1-{(3'R,4'S)-4'-[(6"-Amino-4"-Methylpyridin-2"-Yl) Methyl]Pyrrolidin-3'-Yl}-N2-(3'-Fluorophenethyl)Ethane-1,2-Diamine Tetrahydrochloride
- 3jwz - Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed With N1-[(3' S,4' R)-4'-((6"-Amino-4"-Methylpyridin-2"-Yl)Methyl) Pyrrolidin-3'-Yl]-N2-(3'-Fluorophenethyl)Ethane-1,2-Diamine Tetrahydrochloride
- 3jx0 - Structure of Rat Neuronal Nitric Oxide Synthase D597N Mutant Heme Domain in Complex With N1-{(3'S,4'S)-4'-[(6"-Amino-4"-Methylpyridin- 2"-Yl)Methyl]Pyrrolidin-3'-Yl}-N2-(3'-Fluorophenethyl)Ethane-1,2- Diamine
- 3jx1 - Structure of Rat Neuronal Nitric Oxide Synthase D597N Mutant Heme Domain in Complex With N1-{(3'R,4'R)-4'-[(6"-Amino-4"-Methylpyridin- 2"-Yl)Methyl]Pyrrolidin-3'-Yl}-N2-(3'-Fluorophenethyl)Ethane-1,2- Diamine
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| We would like to acknowledge that these pictures of PDB structures of Fluorine coordination spheres were produced with valuable advice from our colleagues from http://3dpdb.com. |