Chemical elements
  Fluorine
    Isotopes
    Energy
    Production
    Application
    PDB 16pk-1c8m
    PDB 1c9d-1eau
    PDB 1ec0-1grn
    PDB 1gs4-1j97
    PDB 1jdj-1mu8
    PDB 1mue-1oyt
    PDB 1oz1-1rby
    PDB 1rbz-1tu6
    PDB 1tuy-1w9i
    PDB 1w9j-1yw2
    PDB 1yw9-2ax8
    PDB 2ax9-2dqt
    PDB 2dqu-2ftk
    PDB 2fvd-2hhn
    PDB 2hiw-2izs
    PDB 2j51-2onh
    PDB 2oo8-2pow
    PDB 2pq9-2qzl
    PDB 2qzo-2vev
    PDB 2vew-2wf7
    PDB 2wf8-2xhd
    PDB 2xkk-3ar9
    PDB 3az8-3cej
    PDB 3cem-3dh3
    PDB 3dhf-3el7
    PDB 3el8-3fln
    PDB 3flq-3gc7
    PDB 3gc8-3h7w
    PDB 3h82-3i81
    PDB 3i8d-3jx1
    PDB 3jx2-3ktk
    PDB 3ktu-3lj6
    PDB 3lk9-3mqf
    PDB 3ms4-3nz7
      3ms4
      3mvh
      3mxe
      3n3g
      3n4l
      3n7o
      3n7r
      3n8w
      3n8z
      3nax
      3nbq
      3new
      3nk8
      3nkk
      3nld
      3nle
      3nlf
      3nlg
      3nlh
      3nli
      3nlj
      3nlk
      3nlm
      3nln
      3nlo
      3nlp
      3nlq
      3nlr
      3nlt
      3nlu
      3nlv
      3nlw
      3nlx
      3nly
      3nlz
      3nm0
      3nm1
      3nnn
      3nns
      3nny
      3nnz
      3nsh
      3ntg
      3nvh
      3nw5
      3nw6
      3nw7
      3nyp
      3nz0
      3nz7
    PDB 3o1g-3p4a
    PDB 3p4b-3ti1
    PDB 3tik-4acx
    PDB 4afe-4fk3
    PDB 4fod-7gch

Fluorine in PDB, part 34 (1651-1700), PDB files 3ms4 - 3nz7






Experimental structures of coordination spheres of Fluorine (F) in bioorganic molecules from X-Ray and NMR experiments. Coordination spheres were calculated with 5.0 Angstroms radius around Fluorine atoms.
PDB files 1651-1700 (3ms4 - 3nz7):
  1. 3ms4 - Glycogen Phosphorylase Complexed With 4-Trifluoromethylbenzaldehyde-4- (Beta-D-Glucopyranosyl)-Thiosemicarbazone
  2. 3mvh - Crystal Structure of Akt-1-Inhibitor Complexes
  3. 3mxe - Crystal Structure of Hiv-1 Protease Inhibitor, KC32 Complexed With Wild-Type Protease
  4. 3n3g - 4-(3-Trifluoromethylphenyl)-Pyrimidine-2-Carbonitrile As Cathepsin S Inhibitors: N3, Not N1 Is Critically Important
  5. 3n4l - Bace-1 in Complex With ELN380842
  6. 3n7o - X-Ray Structure of Human Chymase in Complex With Small Molecule Inhibitor.
  7. 3n7r - Crystal Structure Of The Ectodomain Complex Of The Cgrp Receptor, A Class-B Gpcr, Reveals the Site of Drug Antagonism
  8. 3n8w - Crystal Structure of R120Q/Native Cyclooxygenase-1 Heterodimer Mutant in Complex With Flurbiprofen
  9. 3n8z - Crystal Structure of Cyclooxygenase-1 in Complex With Flurbiprofen
  10. 3nax - PDK1 in Complex With Inhibitor MP7
  11. 3nbq - Human Uridine Phosphorylase 1 (HUPP1) With 5-Fluorouracil
  12. 3new - P38-Alpha Complexed With Compound 10
  13. 3nk8 - Trypsin in Complex With Fluorine-Containing Fragment
  14. 3nkk - Trypsin in Complex With Fluorine Containing Fragment
  15. 3nld - Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed With 6-{{(3'S,4'S)-3'-[2"-(3''-Fluorophenethylamino) Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin-2-Amine
  16. 3nle - Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed With 6-{{(3'R,4'R)-3'-[2"-(3''-Fluorophenethylamino) Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin-2-Amine
  17. 3nlf - Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed With 6-{{(3'R,4'S)-3'-[2"-(3''-Fluorophenethylamino) Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin-2-Amine
  18. 3nlg - Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed With 6-{{(3'S,4'R)-3'-[2"-(3''-Fluorophenethylamino) Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin-2-Amine
  19. 3nlh - Structure of Endothelial Nitric Oxide Synthase Heme Domain N368D Mutant Complexed With 6-{{(3'S,4'S)-3'-[2"-(3''- Fluorophenethylamino)Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin- 2-Amine
  20. 3nli - Structure of Endothelial Nitric Oxide Synthase N368D Mutant Heme Domain Complexed With 6-{{(3'R,4'R)-3'-[2"-(3''- Fluorophenethylamino)Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin- 2-Amine
  21. 3nlj - Structure of Neuronal Nitric Oxide Synthase D597N/M336V/Y706A Triple Mutant Heme Domain Complexed With 6-{{(3'R,4'R)-3'-[2"-(3''- Fluorophenethylamino)Ethoxy] Pyrrolidin-4'-Yl}Methyl}-4- Methylpyridin-2-Amine
  22. 3nlk - Structure of Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex With 6-{{(3'S,4'S)-3'-[2"-(3''-Fluorophenethylamino) Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin-2-Amine
  23. 3nlm - Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex With 6-{{(3'R,4'R)-3'-[2"-(3''-Fluorophenethylamino) Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin-2-Amine
  24. 3nln - Structure of Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex With 6-{{(3'R,4'S)-3'-[2"-(3''-Fluorophenethylamino) Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin-2-Amine
  25. 3nlo - Structure of Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex With 6-{{(3'S,4'R)-3'-[2"-(3''-Fluorophenethylamino) Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin-2-Amine
  26. 3nlp - Structure of Neuronal Nitric Oxide Synthase D597N/M336V Mutant Heme Domain in Complex With 6-{{(3'S,4'S)-3'-[2"-(3''- Fluorophenethylamino)Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin- 2-Amine
  27. 3nlq - Structure of Neuronal Nitric Oxide Synthase D597N/M336V Mutant Heme Domain in Complex With 6-{{(3'R,4'R)-3'-[2"-(3''- Fluorophenethylamino)Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin- 2-Amine
  28. 3nlr - Structure of Neuronal Nitric Oxide Synthase D597N/M336V Mutant Heme Domain in Complex With 6-{{(3'R,4'S)-3'-[2"-(3''- Fluorophenethylamino)Ethoxy]Pyrrolidin-4'-Yl}Methyl}-4-Methylpyridin- 2-Amine
  29. 3nlt - Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed With N1-{(3'S,4'S)-4'-[(6"-Amino-4"-Methylpyridin-2"-Yl) Methyl]Pyrrolidin-3'-Yl}- N2-(3'-Fluorophenethyl)Ethane-1,2-Diamine Tetrahydrochloride
  30. 3nlu - Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed With N1-{(3'R,4'R)-4'-[(6"-Amino-4"-Methylpyridin-2"-Yl) Methyl]Pyrrolidin-3'-Yl}-N2-(3'-Fluorophenethyl)Ethane-1,2-Diamine Tetrahydrochloride
  31. 3nlv - Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex With 6-(((3S,4S)-4-(2-(2,2-Difluoro-2-(3-Fluorophenyl)Ethylamino) Ethoxy)Pyrrolidin-3-Yl)Methyl)-4-Methylpyridin-2-Amine
  32. 3nlw - Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex With 6-(((3S,4S)-4-(2-(2,2-Difluoro-2-(Piperidin-2-Yl)Ethylamino) Ethoxy)Pyrrolidin-3-Yl)Methyl)-4-Methylpyridin-2-Amine
  33. 3nlx - Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex With 6-(((3R,4R)-4-(2- (2,2-Difluoro-2-(3-Fluorophenyl)Ethylamino) Ethoxy)Pyrrolidin-3-Yl)Methyl)-4-Methylpyridin-2-Amine
  34. 3nly - Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex With 6-(((3R,4R)-4-(2- (2,2-Difluoro-2-(4-Fluorophenyl)Ethylamino) Ethoxy)Pyrrolidin-3-Yl)Methyl)-4-Methylpyridin-2-Amine
  35. 3nlz - Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex With 6-(((3R,4R)-4-(2-(2,2-Difluoro-2-Phenylethylamino)Ethoxy) Pyrrolidin-3-Yl)Methyl)-4-Methylpyridin-2-Amine
  36. 3nm0 - Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex With 6-(((3R,4R)-4-(2-(2,2-Difluoro-2-Phenylethylamino)Ethoxy) Pyrrolidin-3-Yl)Methyl)-4-Methyl-3,4,5,6-Tetrahydropyridin-2-Amine
  37. 3nm1 - The Crystal Structure Of Candida Glabrata THI6, A Bifunctional Enzyme Involved in Thiamin Biosyhthesis of Eukaryotes
  38. 3nnn - BEF3 Activated Drrd Receiver Domain
  39. 3nns - BEF3 Activated Drrb Receiver Domain
  40. 3nny - Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain Complexed With 6-(((3R,4R)-4-(2-(3-Fluorophenethylamino)Ethoxy)Pyrrolidin-3- Yl)Methyl)Pyridin-2-Amine
  41. 3nnz - Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain Complexed With 6-(((3S,4S)-4-(2-(3-Fluorophenethylamino)Ethoxy)Pyrrolidin-3- Yl)Methyl)Pyridin-2-Amine
  42. 3nsh - Bace-1 in Complex With ELN475957
  43. 3ntg - Crystal Structure of Cox-2 With Selective Compound 23D-(R)
  44. 3nvh - Mihfgnd Segment 137-143 From Mouse Prion
  45. 3nw5 - Crystal Structure of Insulin-Like Growth Factor 1 Receptor (Igf-1R-Wt) Complex With A Carbon-Linked Proline Isostere Inhibitor (11B)
  46. 3nw6 - Crystal Structure of Insulin-Like Growth Factor 1 Receptor (Igf-1R-Wt) Complex With A Carbon-Linked Proline Isostere Inhibitor (11A)
  47. 3nw7 - Crystal Structure of Insulin-Like Growth Factor 1 Receptor (Igf-1R-Wt) Complex With A Carbon-Linked Proline Isostere Inhibitor (34)
  48. 3nyp - A Bimolecular Anti-Parallel-Stranded Oxytricha Nova Telomeric Quadruplex in Complex With A 3,6-Disubstituted Acridine Ligand Containing Bis-3-Fluoropyrrolidine End Side Chains
  49. 3nz0 - Non-Phosphorylated TYK2 Kinase With CMP6
  50. 3nz7 - A Bimolecular Anti-Parallel-Stranded Oxytricha Nova Telomeric Quadruplex in Complex With A 3,6-Disubstituted Acridine Ligand Containing Bis-3-Fluoropyrrolidine End Side Chains


Acknowledgement

We would like to acknowledge that these pictures of PDB structures of Fluorine coordination spheres were produced with valuable advice from our colleagues from http://3dpdb.com.
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