Chemical elements
  Fluorine
    Isotopes
    Energy
    Production
    Application
    PDB 16pk-1c8m
    PDB 1c9d-1eau
    PDB 1ec0-1grn
    PDB 1gs4-1j97
    PDB 1jdj-1mu8
    PDB 1mue-1oyt
    PDB 1oz1-1rby
    PDB 1rbz-1tu6
    PDB 1tuy-1w9i
    PDB 1w9j-1yw2
    PDB 1yw9-2ax8
    PDB 2ax9-2dqt
    PDB 2dqu-2ftk
    PDB 2fvd-2hhn
    PDB 2hiw-2izs
    PDB 2j51-2onh
    PDB 2oo8-2pow
    PDB 2pq9-2qzl
    PDB 2qzo-2vev
    PDB 2vew-2wf7
    PDB 2wf8-2xhd
    PDB 2xkk-3ar9
    PDB 3az8-3cej
    PDB 3cem-3dh3
    PDB 3dhf-3el7
    PDB 3el8-3fln
    PDB 3flq-3gc7
    PDB 3gc8-3h7w
    PDB 3h82-3i81
    PDB 3i8d-3jx1
    PDB 3jx2-3ktk
    PDB 3ktu-3lj6
    PDB 3lk9-3mqf
    PDB 3ms4-3nz7
    PDB 3o1g-3p4a
    PDB 3p4b-3ti1
    PDB 3tik-4acx
      3tik
      3tkm
      3tpx
      3twf
      3twg
      3tyl
      3u15
      3u7l
      3u7m
      3ufj
      3ufo
      3ufp
      3ufq
      3ufr
      3ufs
      3uft
      3ug2
      3ugc
      3ukd
      3uua
      3v01
      3v04
      3v1x
      3v6h
      3v6j
      3v6k
      3v7t
      3v8t
      3vap
      3vbg
      3vc4
      3vf8
      3vgn
      3vjm
      3vnt
      3vqs
      3vrb
      3vrs
      3zs5
      3zsh
      3zsi
      436d
      460d
      461d
      478d
      4a3h
      4a4x
      4a6v
      4acu
      4acx
    PDB 4afe-4fk3
    PDB 4fod-7gch

Fluorine in PDB, part 37 (1801-1850), PDB files 3tik - 4acx






Experimental structures of coordination spheres of Fluorine (F) in bioorganic molecules from X-Ray and NMR experiments. Coordination spheres were calculated with 5.0 Angstroms radius around Fluorine atoms.
PDB files 1801-1850 (3tik - 4acx):
  1. 3tik - Sterol 14-Alpha Demethylase (CYP51) From Trypanosoma Brucei in Complex With the Tipifarnib Derivative 6-((4-Chlorophenyl)(Methoxy)(1-Methyl- 1H-Imidazol-5-Yl)Methyl)-4-(2,6-Difluorophenyl)-1-Methylquinolin- 2(1H)-One
  2. 3tkm - Crystal Structure Ppar Delta Binding GW0742
  3. 3tpx - Crystal Structure of Human MDM2 in Complex With A Trifluoromethylated D-Peptide Inhibitor
  4. 3twf - Crystal Structure of the De Novo Designed Fluorinated Peptide ALPHA4F3A
  5. 3twg - Crystal Structure of the De Novo Designed Fluorinated Peptide ALPHA4F3AF3D
  6. 3tyl - Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex With 6-(((3S,4S)-4-(2-((2-Fluorobenzyl)Amino)Ethoxy)Pyrrolidin-3-Yl) Methyl)-4-Methylpyridin-2-Amine
  7. 3u15 - Structure of Hdmx With Dimer Inducing Indolyl Hydantoin Ro-2443
  8. 3u7l - Crystal Structures Of the Staphylococcus Aureus Peptide Deformylase in Complex With Two Classes of New Inhibitors
  9. 3u7m - Crystal Structures Of the Staphylococcus Aureus Peptide Deformylase in Complex With Two Classes of New Inhibitors
  10. 3ufj - Human Thymine Dna Glycosylase Bound to Substrate Analog 2'-Fluoro-2'- Deoxyuridine
  11. 3ufo - Structure of Rat Nitric Oxide Synthase Heme Domain in Complex With 6- (((3S,4S)-4-((5-(3-Fluorophenyl)Pentyl)Oxy)Pyrrolidin-3-Yl)Methyl)-4- Methylpyridin-2-Amine
  12. 3ufp - Structure of Rat Nitric Oxide Synthase Heme Domain in Complex With 6- (((3R,4R)-4-((5-(3-Fluorophenyl)Pentyl)Oxy)Pyrrolidin-3-Yl)Methyl)-4- Methylpyridin-2-Amine
  13. 3ufq - Structure of Rat Nitric Oxide Synthase Heme Domain in Complex With 6- (((3S,4S)-4-(((E)-5-(3-Fluorophenyl)Pent-4-En-1-Yl)Oxy)Pyrrolidin-3- Yl)Methyl)-4-Methylpyridin-2-Amine
  14. 3ufr - Structure of Rat Nitric Oxide Synthase Heme Domain in Complex With 6- (((3R,4R)-4-(((E)-5-(3-Fluorophenyl)Pent-4-En-1-Yl)Oxy)Pyrrolidin-3- Yl)Methyl)-4-Methylpyridin-2-Amine
  15. 3ufs - Structure of Rat Nitric Oxide Synthase Heme Domain in Complex With 6- (((3R,4R)-4-((5-(3-Chloro-5-Fluorophenyl)Pentyl)Oxy)Pyrrolidin-3-Yl) Methyl)-4-Methylpyridin-2-Amine
  16. 3uft - Structure of Rat Nitric Oxide Synthase Heme Domain in Complex With 6- (((3R,4R)-4-(4-(3-Chloro-5-Fluorophenoxy)Butoxy)Pyrrolidin-3-Yl) Methyl)-4-Methylpyridin-2-Amine
  17. 3ug2 - Crystal Structure of the Mutated Egfr Kinase Domain (G719S/T790M) in Complex With Gefitinib
  18. 3ugc - Structural Basis of JAK2 Inhibition By the Type II Inhibtor Nvp-BBT594
  19. 3ukd - Ump/Cmp Kinase From Slime Mold Complexed With Adp, Cmp, and ALF3
  20. 3uua - Crystal Structure of Hera-Lbd (Y537S) in Complex With Bisphenol-Af
  21. 3v01 - Discovery of Novel Allosteric Mek Inhibitors Possessing Classical and Non-Classical Bidentate SER212 Interactions.
  22. 3v04 - Discovery of Novel Allosteric Mek Inhibitors Possessing Classical and Non-Classical Bidentate SER212 Interactions.
  23. 3v1x - Crystal Structure of 2-Methylisoborneol Synthase From Streptomyces Coelicolor A3(2) in Complex With MG2+ and 2-Fluorogeranyl Diphosphate
  24. 3v6h - Replication of N2,3-Ethenoguanine By Dna Polymerases
  25. 3v6j - Replication of N2,3-Ethenoguanine By Dna Polymerases
  26. 3v6k - Replication of N2,3-Ethenoguanine By Dna Polymerases
  27. 3v7t - Crystal Structure of Human Beta-Tryptase Complexed With A Synthetic Inhibitor With A Tropanylamide Scaffold
  28. 3v8t - Crystal Structure of Interleukin-2 Inducible T-Cell Kinase Itk Catalytic Domain With Thienopyrazolylindole Inhibitor 477
  29. 3vap - Synthesis and Sar Studies of Imidazo-[1,2-A]-Pyrazine Aurora Kinase Inhibitors With Improved Off Target Kinase Selectivity
  30. 3vbg - Structure of HDM2 With Dimer Inducing Indolyl Hydantoin Ro-2443
  31. 3vc4 - Exploitation of Hydrogen Bonding Constraints And Flat Hydrophobic Energy Landscapes in Pim-1 Kinase Needle Screening and Inhibitor Design
  32. 3vf8 - Crystal Structure of Spleen Tyrosine Kinase Syk Catalytic Domain With Pyrazolylbenzimidazole Inhibitor 416
  33. 3vgn - Crystal Structure of Ketosteroid Isomerase D40N From Pseudomonas Putida (Pksi) With Bound 3-Fluoro-4-Nitrophenol
  34. 3vjm - Crystal Structure of Human Depiptidyl Peptidase IV (Dpp-4) in Complex With A Prolylthiazolidine Inhibitor #1
  35. 3vnt - Crystal Structure Of the Kinase Domain of Human VEGFR2 With A [1, 3]Thiazolo[5,4-B]Pyridine Derivative
  36. 3vqs - Crystal Structure of Hcv NS5B Rna Polymerase With A Novel Piperazine Inhibitor
  37. 3vrb - Mitochondrial Rhodoquinol-Fumarate Reductase From The Parasitic Nematode Ascaris Suum With the Specific Inhibitor Flutolanil and Substrate Fumarate
  38. 3vrs - Crystal Structure of Fluoride Riboswitch, Soaked in MN2+
  39. 3zs5 - Structural Basis For Kinase Selectivity of Three Clinical P38ALPHA Inhibitors
  40. 3zsh - X-Ray Structure of P38ALPHA Bound to Scio-469
  41. 3zsi - X-Ray Structure of P38ALPHA Bound to Vx-745
  42. 436d - The Dickerson-Drew B-Dna Dodecamer Revisited-At Atomic Resolution
  43. 460d - A "Hydrat-Ion Spine" in A B-Dna Minor Groove
  44. 461d - A "Hydrat-Ion Spine" in A B-Dna Minor Groove
  45. 478d - Crystal Structure of the B-Dna Dodecamer 5'-D(Cgcgaa(Taf)Tcgcg), Where Taf Is 2'-Deoxy-2'-Fluoro-Arabino-Furanosyl Thymine
  46. 4a3h - 2',4' Dinitrophenyl-2-Deoxy-2-Fluro-B-D-Cellobioside Complex of the Endoglucanase CEL5A From Bacillus Agaradhaerens At 1.6 A Resolution
  47. 4a4x - NEK2-Ede Bound to CCT248662
  48. 4a6v - X-Ray Structures of Oxazole Hydroxamate Ecmetap-Mn Complexes
  49. 4acu - Aminoimidazoles As Bace-1 Inhibitors. X-Ray Crystal Structure of Beta Secretase Complexed With Compound 14
  50. 4acx - Aminoimidazoles As Bace-1 Inhibitors. X-Ray Crystal Structure of Beta Secretase Complexed With Compound 23


Acknowledgement

We would like to acknowledge that these pictures of PDB structures of Fluorine coordination spheres were produced with valuable advice from our colleagues from http://3dpdb.com.
© Copyright 2008-2012 by atomistry.com