Fluorine in PDB 6v31: Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and CH5126766

Enzymatic activity of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and CH5126766

All present enzymatic activity of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and CH5126766:
2.7.11.1; 2.7.12.2;

Protein crystallography data

The structure of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and CH5126766, PDB code: 6v31 was solved by K.Li, G.Gonzalez Del-Pino, E.Park, M.J.Eck, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 43.33 / 3.12
Space group P 31 2 1
Cell size a, b, c (Å), α, β, γ (°) 116.784, 116.784, 129.256, 90.00, 90.00, 120.00
R / Rfree (%) 18.3 / 22.4

Other elements in 6v31:

The structure of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and CH5126766 also contains other interesting chemical elements:

Magnesium (Mg) 1 atom

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and CH5126766 (pdb code 6v31). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and CH5126766, PDB code: 6v31:

Fluorine binding site 1 out of 1 in 6v31

Go back to Fluorine Binding Sites List in 6v31
Fluorine binding site 1 out of 1 in the Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and CH5126766


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and CH5126766 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F401

b:78.3
occ:1.00
 F33 B:CHU401 0.0 78.3 1.0
C22 B:CHU401 1.4 74.3 1.0
C14 B:CHU401 2.4 78.9 1.0
C23 B:CHU401 2.4 79.5 1.0
N27 B:CHU401 2.8 93.9 1.0
C13 B:CHU401 3.1 62.3 1.0
CA B:ILE216 3.1 76.5 1.0
CB B:MET219 3.4 62.2 1.0
C26 B:CHU401 3.6 94.0 1.0
CE B:MET219 3.6 74.0 1.0
N24 B:CHU401 3.6 69.1 1.0
O B:LEU215 3.7 77.9 1.0
O B:ILE216 3.7 75.7 1.0
CB B:ILE216 3.9 68.3 1.0
CG1 B:ILE216 3.9 71.0 1.0
C B:ILE216 3.9 77.2 1.0
N B:ILE216 3.9 77.1 1.0
CG B:MET219 4.0 91.5 1.0
CG2 B:ILE216 4.0 69.2 1.0
C25 B:CHU401 4.1 85.2 1.0
C B:LEU215 4.1 73.2 1.0
S28 B:CHU401 4.4 79.7 1.0
C8 B:CHU401 4.5 69.5 1.0
SD B:MET219 4.7 97.6 1.0
CA B:MET219 4.7 74.5 1.0
C12 B:CHU401 4.9 62.9 1.0
N B:MET219 4.9 81.6 1.0
O32 B:CHU401 4.9 71.5 1.0

Reference:

K.Li, G.Gonzalez Del-Pino, E.Park, M.J.Eck. Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and CH5126766 To Be Published.
Page generated: Sun Dec 13 13:22:44 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy