Fluorine in PDB 7g8a: ARHGEF2 Pandda Analysis Group Deposition -- ARHGEF2 and Rhoa in Complex with Z100642432

Enzymatic activity of ARHGEF2 Pandda Analysis Group Deposition -- ARHGEF2 and Rhoa in Complex with Z100642432

All present enzymatic activity of ARHGEF2 Pandda Analysis Group Deposition -- ARHGEF2 and Rhoa in Complex with Z100642432:
3.6.5.2;

Protein crystallography data

The structure of ARHGEF2 Pandda Analysis Group Deposition -- ARHGEF2 and Rhoa in Complex with Z100642432, PDB code: 7g8a was solved by W.J.Bradshaw, V.L.Katis, C.Bountra, F.Von Delft, P.E.Brennan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 35.67 / 1.50
Space group P 43 21 2
Cell size a, b, c (Å), α, β, γ (°) 71.341, 71.341, 196.493, 90, 90, 90
R / Rfree (%) 18.7 / 21.1

Other elements in 7g8a:

The structure of ARHGEF2 Pandda Analysis Group Deposition -- ARHGEF2 and Rhoa in Complex with Z100642432 also contains other interesting chemical elements:

Bromine (Br) 1 atom

Fluorine Binding Sites:

The binding sites of Fluorine atom in the ARHGEF2 Pandda Analysis Group Deposition -- ARHGEF2 and Rhoa in Complex with Z100642432 (pdb code 7g8a). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the ARHGEF2 Pandda Analysis Group Deposition -- ARHGEF2 and Rhoa in Complex with Z100642432, PDB code: 7g8a:

Fluorine binding site 1 out of 1 in 7g8a

Go back to Fluorine Binding Sites List in 7g8a
Fluorine binding site 1 out of 1 in the ARHGEF2 Pandda Analysis Group Deposition -- ARHGEF2 and Rhoa in Complex with Z100642432


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of ARHGEF2 Pandda Analysis Group Deposition -- ARHGEF2 and Rhoa in Complex with Z100642432 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F201

b:41.8
occ:0.80
 F A:WJ7201 0.0 41.8 0.8
C6 A:WJ7201 1.4 42.9 0.8
C5 A:WJ7201 2.3 43.5 0.8
C7 A:WJ7201 2.4 43.3 0.8
N A:PRO75 3.3 18.4 1.0
O A:PHE106 3.4 23.2 1.0
C A:TYR74 3.5 18.5 1.0
CB A:TYR74 3.5 17.3 1.0
CA A:PRO75 3.5 19.6 1.0
O A:HOH360 3.5 28.1 1.0
C4 A:WJ7201 3.6 44.0 0.8
CD A:PRO75 3.6 18.7 1.0
C8 A:WJ7201 3.7 44.4 0.8
CG A:PRO75 3.8 21.0 1.0
O A:TYR74 3.8 18.8 1.0
O B:HOH654 4.0 48.6 1.0
O A:HOH391 4.0 28.7 1.0
CA A:TYR74 4.1 16.9 1.0
CB A:PHE106 4.1 20.8 1.0
C3 A:WJ7201 4.1 44.6 0.8
CB A:PRO75 4.3 20.6 1.0
C A:PHE106 4.3 22.8 1.0
O A:PRO71 4.3 18.8 1.0
CD1 A:PHE106 4.5 22.3 1.0
CA A:PHE106 4.5 21.4 1.0
CG A:PHE106 4.7 20.6 1.0
C A:PRO75 4.8 20.0 1.0
N A:TYR74 4.8 16.8 1.0
O2 B:FMT513 4.8 47.0 1.0
CG A:TYR74 4.8 19.2 1.0

Reference:

W.J.Bradshaw, V.L.Katis, C.Bountra, F.Von Delft, P.E.Brennan. ARHGEF2 Pandda Analysis Group Deposition To Be Published.
Page generated: Fri Aug 2 07:27:51 2024

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