Fluorine in PDB 7g8t: ARHGEF2 Pandda Analysis Group Deposition -- ARHGEF2 and Rhoa in Complex with Z1273312142

Enzymatic activity of ARHGEF2 Pandda Analysis Group Deposition -- ARHGEF2 and Rhoa in Complex with Z1273312142

All present enzymatic activity of ARHGEF2 Pandda Analysis Group Deposition -- ARHGEF2 and Rhoa in Complex with Z1273312142:
3.6.5.2;

Protein crystallography data

The structure of ARHGEF2 Pandda Analysis Group Deposition -- ARHGEF2 and Rhoa in Complex with Z1273312142, PDB code: 7g8t was solved by W.J.Bradshaw, V.L.Katis, C.Bountra, F.Von Delft, P.E.Brennan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.28 / 1.39
Space group P 43 21 2
Cell size a, b, c (Å), α, β, γ (°) 71.038, 71.038, 196.314, 90, 90, 90
R / Rfree (%) 18 / 19.8

Fluorine Binding Sites:

The binding sites of Fluorine atom in the ARHGEF2 Pandda Analysis Group Deposition -- ARHGEF2 and Rhoa in Complex with Z1273312142 (pdb code 7g8t). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the ARHGEF2 Pandda Analysis Group Deposition -- ARHGEF2 and Rhoa in Complex with Z1273312142, PDB code: 7g8t:

Fluorine binding site 1 out of 1 in 7g8t

Go back to Fluorine Binding Sites List in 7g8t
Fluorine binding site 1 out of 1 in the ARHGEF2 Pandda Analysis Group Deposition -- ARHGEF2 and Rhoa in Complex with Z1273312142


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of ARHGEF2 Pandda Analysis Group Deposition -- ARHGEF2 and Rhoa in Complex with Z1273312142 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F501

b:45.1
occ:0.60
 F06 B:Z4X501 0.0 45.1 0.6
C05 B:Z4X501 1.4 45.2 0.6
C07 B:Z4X501 2.4 44.7 0.6
C04 B:Z4X501 2.4 45.7 0.6
O03 B:Z4X501 2.8 45.9 0.6
O B:HOH688 2.8 23.0 1.0
C02 B:Z4X501 3.2 45.8 0.6
CB B:SER330 3.6 22.1 1.0
C08 B:Z4X501 3.6 44.7 0.6
C10 B:Z4X501 3.7 45.8 0.6
CA B:SER330 4.1 20.4 1.0
C09 B:Z4X501 4.1 45.2 0.6
O B:HOH691 4.2 44.9 1.0
NH2 B:ARG292 4.4 37.6 1.0
CD B:ARG292 4.5 28.0 1.0
CA B:ILE289 4.5 15.5 1.0
CG1 B:ILE289 4.6 18.7 1.0
C01 B:Z4X501 4.7 45.6 0.6
CZ B:ARG292 4.8 38.3 1.0
NE B:ARG292 4.8 33.8 1.0
O B:SER330 4.9 20.2 1.0
OG B:SER330 4.9 22.2 1.0
C11 B:Z4X501 4.9 46.4 0.6
CB B:ILE289 5.0 17.8 1.0
O B:ILE289 5.0 15.8 1.0

Reference:

W.J.Bradshaw, V.L.Katis, C.Bountra, F.Von Delft, P.E.Brennan. ARHGEF2 Pandda Analysis Group Deposition To Be Published.
Page generated: Fri Aug 2 07:30:17 2024

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