Fluorine in PDB 7kdp: Hcmv Prefusion Gb in Complex with Fusion Inhibitor Way-174865

The structure of Hcmv Prefusion Gb in Complex with Fusion Inhibitor Way-174865 also contains other interesting chemical elements:

Calcium

(Ca)

1 atom

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 18;

Binding sites:

The binding sites of Fluorine atom in the Hcmv Prefusion Gb in Complex with Fusion Inhibitor Way-174865 (pdb code 7kdp). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 18 binding sites of Fluorine where determined in the Hcmv Prefusion Gb in Complex with Fusion Inhibitor Way-174865, PDB code: 7kdp:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Fluorine binding site 1 out of 18 in the Hcmv Prefusion Gb in Complex with Fusion Inhibitor Way-174865


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Hcmv Prefusion Gb in Complex with Fusion Inhibitor Way-174865 within 5.0Å range: probe atom residue distance (Å) B Occ A:F1011 b:70.5 occ:1.00 F10 A:WCY1011 0.0 70.5 1.0 C9 A:WCY1011 1.3 70.5 1.0 F11 A:WCY1011 2.1 70.5 1.0 F12 A:WCY1011 2.1 70.5 1.0 C7 A:WCY1011 2.4 70.5 1.0 C6 A:WCY1011 2.7 70.5 1.0 CE2 A:PHE747 3.4 64.9 1.0 C8 A:WCY1011 3.6 70.5 1.0 CD2 A:PHE747 3.8 64.9 1.0 C5 A:WCY1011 4.1 70.5 1.0 CZ A:PHE747 4.4 64.9 1.0 C3 A:WCY1011 4.8 70.5 1.0 ND2 A:ASN750 4.8 70.7 1.0 N A:GLY753 4.8 68.4 1.0 F14 A:WCY1011 4.9 70.5 1.0 C4 A:WCY1011 4.9 70.5 1.0 CG A:PHE747 5.0 64.9 1.0

Fluorine binding site 2 out of 18 in the Hcmv Prefusion Gb in Complex with Fusion Inhibitor Way-174865


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Hcmv Prefusion Gb in Complex with Fusion Inhibitor Way-174865 within 5.0Å range: probe atom residue distance (Å) B Occ A:F1011 b:70.5 occ:1.00 F11 A:WCY1011 0.0 70.5 1.0 C9 A:WCY1011 1.3 70.5 1.0 F10 A:WCY1011 2.1 70.5 1.0 F12 A:WCY1011 2.1 70.5 1.0 C7 A:WCY1011 2.4 70.5 1.0 C8 A:WCY1011 3.1 70.5 1.0 C6 A:WCY1011 3.3 70.5 1.0 CB A:PHE752 3.4 70.5 1.0 N A:GLY753 3.9 68.4 1.0 ND2 A:ASN750 4.0 70.7 1.0 CD2 A:PHE752 4.0 70.5 1.0 CB A:ASN750 4.0 70.7 1.0 CG A:PHE752 4.2 70.5 1.0 CA A:PHE752 4.3 70.5 1.0 C3 A:WCY1011 4.3 70.5 1.0 C A:PHE752 4.4 70.5 1.0 C5 A:WCY1011 4.5 70.5 1.0 CG A:ASN750 4.6 70.7 1.0 S19 A:WCY1011 4.6 70.5 1.0 N A:PHE752 4.6 70.5 1.0 CA A:GLY753 4.7 68.4 1.0 C4 A:WCY1011 4.9 70.5 1.0

Fluorine binding site 3 out of 18 in the Hcmv Prefusion Gb in Complex with Fusion Inhibitor Way-174865


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Hcmv Prefusion Gb in Complex with Fusion Inhibitor Way-174865 within 5.0Å range: probe atom residue distance (Å) B Occ A:F1011 b:70.5 occ:1.00 F12 A:WCY1011 0.0 70.5 1.0 C9 A:WCY1011 1.3 70.5 1.0 F11 A:WCY1011 2.1 70.5 1.0 F10 A:WCY1011 2.1 70.5 1.0 C7 A:WCY1011 2.4 70.5 1.0 C8 A:WCY1011 2.9 70.5 1.0 C6 A:WCY1011 3.5 70.5 1.0 C3 A:WCY1011 4.2 70.5 1.0 CB A:PHE752 4.6 70.5 1.0 CD2 A:PHE752 4.6 70.5 1.0 C5 A:WCY1011 4.7 70.5 1.0 C4 A:WCY1011 4.9 70.5 1.0 S19 A:WCY1011 5.0 70.5 1.0

Fluorine binding site 4 out of 18 in the Hcmv Prefusion Gb in Complex with Fusion Inhibitor Way-174865


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Hcmv Prefusion Gb in Complex with Fusion Inhibitor Way-174865 within 5.0Å range: probe atom residue distance (Å) B Occ A:F1011 b:70.5 occ:1.00 F14 A:WCY1011 0.0 70.5 1.0 C13 A:WCY1011 1.3 70.5 1.0 F16 A:WCY1011 2.1 70.5 1.0 F15 A:WCY1011 2.1 70.5 1.0 C5 A:WCY1011 2.4 70.5 1.0 C6 A:WCY1011 2.9 70.5 1.0 C4 A:WCY1011 3.5 70.5 1.0 C7 A:WCY1011 4.2 70.5 1.0 C3 A:WCY1011 4.7 70.5 1.0 ND2 A:ASN750 4.9 70.7 1.0 F10 A:WCY1011 4.9 70.5 1.0 C8 A:WCY1011 4.9 70.5 1.0

Fluorine binding site 5 out of 18 in the Hcmv Prefusion Gb in Complex with Fusion Inhibitor Way-174865


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of Hcmv Prefusion Gb in Complex with Fusion Inhibitor Way-174865 within 5.0Å range: probe atom residue distance (Å) B Occ A:F1011 b:70.5 occ:1.00 F15 A:WCY1011 0.0 70.5 1.0 C13 A:WCY1011 1.3 70.5 1.0 F16 A:WCY1011 2.1 70.5 1.0 F14 A:WCY1011 2.1 70.5 1.0 C5 A:WCY1011 2.4 70.5 1.0 C4 A:WCY1011 2.7 70.5 1.0 C6 A:WCY1011 3.6 70.5 1.0 C3 A:WCY1011 4.1 70.5 1.0 ND2 A:ASN750 4.6 70.7 1.0 C7 A:WCY1011 4.7 70.5 1.0 C1 A:WCY1011 4.8 70.5 1.0 C8 A:WCY1011 4.9 70.5 1.0

Fluorine binding site 6 out of 18 in the Hcmv Prefusion Gb in Complex with Fusion Inhibitor Way-174865


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of Hcmv Prefusion Gb in Complex with Fusion Inhibitor Way-174865 within 5.0Å range: probe atom residue distance (Å) B Occ A:F1011 b:70.5 occ:1.00 F16 A:WCY1011 0.0 70.5 1.0 C13 A:WCY1011 1.3 70.5 1.0 F15 A:WCY1011 2.1 70.5 1.0 F14 A:WCY1011 2.1 70.5 1.0 C5 A:WCY1011 2.4 70.5 1.0 C6 A:WCY1011 3.1 70.5 1.0 C4 A:WCY1011 3.3 70.5 1.0 ND2 A:ASN750 3.4 70.7 1.0 O A:THR746 4.0 67.1 1.0 CG A:ASN750 4.2 70.7 1.0 C7 A:WCY1011 4.3 70.5 1.0 CG2 A:THR746 4.4 67.1 1.0 C3 A:WCY1011 4.5 70.5 1.0 CA A:PHE747 4.5 64.9 1.0 C A:THR746 4.5 67.1 1.0 OD1 A:ASN750 4.5 70.7 1.0 N A:PHE747 4.7 64.9 1.0 C8 A:WCY1011 4.9 70.5 1.0

Fluorine binding site 7 out of 18 in the Hcmv Prefusion Gb in Complex with Fusion Inhibitor Way-174865


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 7 of Hcmv Prefusion Gb in Complex with Fusion Inhibitor Way-174865 within 5.0Å range: probe atom residue distance (Å) B Occ B:F1101 b:70.5 occ:1.00 F10 B:WCY1101 0.0 70.5 1.0 C9 B:WCY1101 1.3 70.5 1.0 F11 B:WCY1101 2.1 70.5 1.0 F12 B:WCY1101 2.1 70.5 1.0 C7 B:WCY1101 2.4 70.5 1.0 C6 B:WCY1101 2.7 70.5 1.0 CE2 B:PHE747 3.4 64.9 1.0 C8 B:WCY1101 3.6 70.5 1.0 CD2 B:PHE747 3.8 64.9 1.0 C5 B:WCY1101 4.1 70.5 1.0 CZ B:PHE747 4.4 64.9 1.0 C3 B:WCY1101 4.8 70.5 1.0 ND2 B:ASN750 4.8 70.7 1.0 N B:GLY753 4.8 68.4 1.0 F14 B:WCY1101 4.9 70.5 1.0 C4 B:WCY1101 4.9 70.5 1.0 CG B:PHE747 5.0 64.9 1.0

Fluorine binding site 8 out of 18 in the Hcmv Prefusion Gb in Complex with Fusion Inhibitor Way-174865


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 8 of Hcmv Prefusion Gb in Complex with Fusion Inhibitor Way-174865 within 5.0Å range: probe atom residue distance (Å) B Occ B:F1101 b:70.5 occ:1.00 F11 B:WCY1101 0.0 70.5 1.0 C9 B:WCY1101 1.3 70.5 1.0 F10 B:WCY1101 2.1 70.5 1.0 F12 B:WCY1101 2.1 70.5 1.0 C7 B:WCY1101 2.4 70.5 1.0 C8 B:WCY1101 3.1 70.5 1.0 C6 B:WCY1101 3.3 70.5 1.0 CB B:PHE752 3.4 70.5 1.0 N B:GLY753 3.9 68.4 1.0 ND2 B:ASN750 4.0 70.7 1.0 CB B:ASN750 4.0 70.7 1.0 CD2 B:PHE752 4.0 70.5 1.0 CG B:PHE752 4.2 70.5 1.0 CA B:PHE752 4.3 70.5 1.0 C3 B:WCY1101 4.3 70.5 1.0 C B:PHE752 4.4 70.5 1.0 C5 B:WCY1101 4.5 70.5 1.0 CG B:ASN750 4.6 70.7 1.0 S19 B:WCY1101 4.6 70.5 1.0 N B:PHE752 4.6 70.5 1.0 CA B:GLY753 4.7 68.4 1.0 C4 B:WCY1101 4.9 70.5 1.0

Fluorine binding site 9 out of 18 in the Hcmv Prefusion Gb in Complex with Fusion Inhibitor Way-174865


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 9 of Hcmv Prefusion Gb in Complex with Fusion Inhibitor Way-174865 within 5.0Å range: probe atom residue distance (Å) B Occ B:F1101 b:70.5 occ:1.00 F12 B:WCY1101 0.0 70.5 1.0 C9 B:WCY1101 1.3 70.5 1.0 F11 B:WCY1101 2.1 70.5 1.0 F10 B:WCY1101 2.1 70.5 1.0 C7 B:WCY1101 2.4 70.5 1.0 C8 B:WCY1101 2.9 70.5 1.0 C6 B:WCY1101 3.5 70.5 1.0 C3 B:WCY1101 4.2 70.5 1.0 CB B:PHE752 4.6 70.5 1.0 CD2 B:PHE752 4.6 70.5 1.0 C5 B:WCY1101 4.7 70.5 1.0 C4 B:WCY1101 4.9 70.5 1.0 S19 B:WCY1101 5.0 70.5 1.0

Fluorine binding site 10 out of 18 in the Hcmv Prefusion Gb in Complex with Fusion Inhibitor Way-174865


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 10 of Hcmv Prefusion Gb in Complex with Fusion Inhibitor Way-174865 within 5.0Å range: probe atom residue distance (Å) B Occ B:F1101 b:70.5 occ:1.00 F14 B:WCY1101 0.0 70.5 1.0 C13 B:WCY1101 1.3 70.5 1.0 F15 B:WCY1101 2.1 70.5 1.0 F16 B:WCY1101 2.1 70.5 1.0 C5 B:WCY1101 2.4 70.5 1.0 C6 B:WCY1101 2.9 70.5 1.0 C4 B:WCY1101 3.5 70.5 1.0 C7 B:WCY1101 4.2 70.5 1.0 C3 B:WCY1101 4.7 70.5 1.0 ND2 B:ASN750 4.9 70.7 1.0 F10 B:WCY1101 4.9 70.5 1.0 C8 B:WCY1101 4.9 70.5 1.0

Y.Liu, K.P.Heim, Y.Che, X.Chi, X.Qiu, S.Han, P.R.Dormitzer, X.Yang. Prefusion Structure of Human Cytomegalovirus Glycoprotein B and Structural Basis For Membrane Fusion. Sci Adv V. 7 2021.
ISSN: ESSN 2375-2548
PubMed: 33674318
DOI: 10.1126/SCIADV.ABF3178