Fluorine in PDB 7kle: Ternary Structure of DPO4 Bound to N7MG in the Template Base Paired with Incoming Dctp

Enzymatic activity of Ternary Structure of DPO4 Bound to N7MG in the Template Base Paired with Incoming Dctp

All present enzymatic activity of Ternary Structure of DPO4 Bound to N7MG in the Template Base Paired with Incoming Dctp:
2.7.7.7;

Protein crystallography data

The structure of Ternary Structure of DPO4 Bound to N7MG in the Template Base Paired with Incoming Dctp, PDB code: 7kle was solved by M.-C.Koag, S.Lee, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.56 / 3.00
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 99.65, 102.472, 53.034, 90, 90, 90
R / Rfree (%) 22.9 / 28.8

Other elements in 7kle:

The structure of Ternary Structure of DPO4 Bound to N7MG in the Template Base Paired with Incoming Dctp also contains other interesting chemical elements:

Calcium (Ca) 3 atoms

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Ternary Structure of DPO4 Bound to N7MG in the Template Base Paired with Incoming Dctp (pdb code 7kle). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Ternary Structure of DPO4 Bound to N7MG in the Template Base Paired with Incoming Dctp, PDB code: 7kle:

Fluorine binding site 1 out of 1 in 7kle

Go back to Fluorine Binding Sites List in 7kle
Fluorine binding site 1 out of 1 in the Ternary Structure of DPO4 Bound to N7MG in the Template Base Paired with Incoming Dctp


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Ternary Structure of DPO4 Bound to N7MG in the Template Base Paired with Incoming Dctp within 5.0Å range:
probe atom residue distance (Å) B Occ
T:F6

b:47.4
occ:1.00
 F1' T:FMG6 0.0 47.4 1.0
C2' T:FMG6 1.4 46.5 1.0
C3' T:FMG6 2.4 53.9 1.0
C1' T:FMG6 2.4 43.8 1.0
N9 T:FMG6 2.8 39.6 1.0
C8 T:FMG6 2.9 44.7 1.0
NH2 A:ARG332 2.9 50.7 1.0
C4' T:FMG6 3.1 53.2 1.0
O4' T:FMG6 3.1 52.2 1.0
CZ A:ARG332 3.4 53.0 1.0
C5' T:FMG6 3.4 56.9 1.0
C8 T:DG7 3.4 37.9 1.0
NH1 A:ARG332 3.5 55.6 1.0
O3' T:FMG6 3.6 55.6 1.0
N7 T:DG7 3.6 39.8 1.0
C4 T:FMG6 4.0 42.3 1.0
OP2 T:DG7 4.0 59.7 1.0
N7 T:FMG6 4.1 48.8 1.0
P T:DG7 4.3 59.4 1.0
NE A:ARG332 4.4 63.8 1.0
N9 T:DG7 4.5 36.3 1.0
O5' T:FMG6 4.5 63.9 1.0
O5' T:DG7 4.5 52.5 1.0
O4' T:DG7 4.6 39.2 1.0
C5 T:FMG6 4.6 46.6 1.0
C5 T:DG7 4.7 38.5 1.0
OP2 T:FMG6 4.9 78.0 1.0
N3 T:FMG6 5.0 40.0 1.0
CM7 T:FMG6 5.0 41.3 1.0

Reference:

M.-C.Koag, S.Lee. Structure of Human Dna Polymerase Beta Complexed with 8OA in the Template Base Paired with Incoming Non-Hydrolyzable Atp To Be Published.
Page generated: Fri Nov 5 13:12:59 2021

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