Fluorine in PDB 7kro: Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - NSP13(2)-Btc

Enzymatic activity of Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - NSP13(2)-Btc

All present enzymatic activity of Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - NSP13(2)-Btc:
2.7.7.48; 3.6.4.12; 3.6.4.13;

Other elements in 7kro:

The structure of Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - NSP13(2)-Btc also contains other interesting chemical elements:

Aluminium (Al) 2 atoms
Zinc (Zn) 8 atoms
Magnesium (Mg) 3 atoms

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - NSP13(2)-Btc (pdb code 7kro). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 6 binding sites of Fluorine where determined in the Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - NSP13(2)-Btc, PDB code: 7kro:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6;

Fluorine binding site 1 out of 6 in 7kro

Go back to Fluorine Binding Sites List in 7kro
Fluorine binding site 1 out of 6 in the Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - NSP13(2)-Btc


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - NSP13(2)-Btc within 5.0Å range:
probe atom residue distance (Å) B Occ
E:F706

b:71.1
occ:1.00
 F1 E:AF3706 0.0 71.1 1.0
AL E:AF3706 1.8 71.1 1.0
O3B E:ADP704 2.5 78.7 1.0
NH2 E:ARG567 2.6 68.8 1.0
O1B E:ADP704 2.9 78.7 1.0
F2 E:AF3706 3.1 71.1 1.0
F3 E:AF3706 3.1 71.1 1.0
PB E:ADP704 3.2 78.7 1.0
CZ E:ARG567 3.2 68.8 1.0
NE E:ARG567 3.5 68.8 1.0
NH1 E:ARG443 3.5 74.5 1.0
N E:GLY538 3.7 81.3 1.0
NH2 E:ARG443 3.8 74.5 1.0
MG E:MG705 4.0 54.6 1.0
CA E:GLY538 4.1 81.3 1.0
O3A E:ADP704 4.1 78.7 1.0
NH1 E:ARG567 4.1 68.8 1.0
CZ E:ARG443 4.2 74.5 1.0
N E:GLY285 4.3 75.2 1.0
C E:GLN537 4.4 79.3 1.0
OE1 E:GLN404 4.4 66.9 1.0
O2B E:ADP704 4.5 78.7 1.0
CA E:GLN537 4.6 79.3 1.0
CB E:PRO284 4.6 72.2 1.0
C E:GLY538 4.6 81.3 1.0
CD E:ARG567 4.7 68.8 1.0
O E:SER539 4.8 81.5 1.0
CA E:PRO284 4.8 72.2 1.0
O1A E:ADP704 5.0 78.7 1.0
C E:PRO284 5.0 72.2 1.0
CA E:GLY285 5.0 75.2 1.0

Fluorine binding site 2 out of 6 in 7kro

Go back to Fluorine Binding Sites List in 7kro
Fluorine binding site 2 out of 6 in the Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - NSP13(2)-Btc


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - NSP13(2)-Btc within 5.0Å range:
probe atom residue distance (Å) B Occ
E:F706

b:71.1
occ:1.00
 F2 E:AF3706 0.0 71.1 1.0
AL E:AF3706 1.8 71.1 1.0
OE1 E:GLN404 2.2 66.9 1.0
O1B E:ADP704 3.1 78.7 1.0
F1 E:AF3706 3.1 71.1 1.0
F3 E:AF3706 3.1 71.1 1.0
CB E:PRO284 3.3 72.2 1.0
CA E:PRO284 3.3 72.2 1.0
CD E:GLN404 3.3 66.9 1.0
CE E:LYS288 4.0 61.5 1.0
PB E:ADP704 4.0 78.7 1.0
NZ E:LYS288 4.1 61.5 1.0
CG E:GLN404 4.1 66.9 1.0
O3B E:ADP704 4.2 78.7 1.0
N E:PRO284 4.2 72.2 1.0
NH2 E:ARG567 4.2 68.8 1.0
NE2 E:GLN404 4.2 66.9 1.0
N E:GLY285 4.3 75.2 1.0
C E:PRO284 4.3 72.2 1.0
CG E:PRO284 4.6 72.2 1.0
O2B E:ADP704 4.6 78.7 1.0
OE1 E:GLU375 4.6 62.0 1.0
CG E:GLN537 4.7 79.3 1.0
MG E:MG705 4.7 54.6 1.0
OE2 E:GLU375 4.7 62.0 1.0
CB E:ASP401 4.8 60.9 1.0
CD E:PRO284 4.8 72.2 1.0
C E:PRO283 4.9 73.4 1.0
CZ E:ARG567 4.9 68.8 1.0
O E:PRO283 4.9 73.4 1.0

Fluorine binding site 3 out of 6 in 7kro

Go back to Fluorine Binding Sites List in 7kro
Fluorine binding site 3 out of 6 in the Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - NSP13(2)-Btc


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - NSP13(2)-Btc within 5.0Å range:
probe atom residue distance (Å) B Occ
E:F706

b:71.1
occ:1.00
 F3 E:AF3706 0.0 71.1 1.0
AL E:AF3706 1.8 71.1 1.0
MG E:MG705 2.1 54.6 1.0
OE2 E:GLU375 2.3 62.0 1.0
O3B E:ADP704 2.5 78.7 1.0
PB E:ADP704 3.1 78.7 1.0
F2 E:AF3706 3.1 71.1 1.0
F1 E:AF3706 3.1 71.1 1.0
CD E:GLU375 3.1 62.0 1.0
O2B E:ADP704 3.3 78.7 1.0
O1B E:ADP704 3.5 78.7 1.0
OE1 E:GLU375 3.5 62.0 1.0
OG E:SER289 4.0 63.1 1.0
CA E:GLY538 4.0 81.3 1.0
N E:GLY538 4.2 81.3 1.0
CG E:GLU375 4.3 62.0 1.0
C E:GLN537 4.4 79.3 1.0
O E:GLN537 4.5 79.3 1.0
CE E:LYS288 4.5 61.5 1.0
O3A E:ADP704 4.6 78.7 1.0
OE1 E:GLN404 4.6 66.9 1.0
OD1 E:ASP374 4.7 58.1 1.0
CG E:GLN537 4.7 79.3 1.0

Fluorine binding site 4 out of 6 in 7kro

Go back to Fluorine Binding Sites List in 7kro
Fluorine binding site 4 out of 6 in the Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - NSP13(2)-Btc


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - NSP13(2)-Btc within 5.0Å range:
probe atom residue distance (Å) B Occ
F:F1005

b:141.0
occ:1.00
 F1 F:AF31005 0.0 141.0 1.0
AL F:AF31005 1.8 141.0 1.0
O3B F:ADP1003 2.5 150.4 1.0
NH2 F:ARG567 2.6 150.1 1.0
O1B F:ADP1003 2.9 150.4 1.0
F2 F:AF31005 3.1 141.0 1.0
F3 F:AF31005 3.1 141.0 1.0
PB F:ADP1003 3.2 150.4 1.0
CZ F:ARG567 3.2 150.1 1.0
NE F:ARG567 3.5 150.1 1.0
NH1 F:ARG443 3.5 153.5 1.0
N F:GLY538 3.7 149.2 1.0
NH2 F:ARG443 3.8 153.5 1.0
MG F:MG1004 4.0 121.4 1.0
CA F:GLY538 4.1 149.2 1.0
O3A F:ADP1003 4.1 150.4 1.0
NH1 F:ARG567 4.1 150.1 1.0
CZ F:ARG443 4.2 153.5 1.0
N F:GLY285 4.3 147.7 1.0
C F:GLN537 4.4 143.0 1.0
OE1 F:GLN404 4.4 136.6 1.0
O2B F:ADP1003 4.5 150.4 1.0
CA F:GLN537 4.6 143.0 1.0
CB F:PRO284 4.6 143.5 1.0
C F:GLY538 4.7 149.2 1.0
CD F:ARG567 4.7 150.1 1.0
O F:SER539 4.8 152.7 1.0
CA F:PRO284 4.8 143.5 1.0
O2A F:ADP1003 5.0 150.4 1.0
C F:PRO284 5.0 143.5 1.0
CA F:GLY285 5.0 147.7 1.0

Fluorine binding site 5 out of 6 in 7kro

Go back to Fluorine Binding Sites List in 7kro
Fluorine binding site 5 out of 6 in the Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - NSP13(2)-Btc


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - NSP13(2)-Btc within 5.0Å range:
probe atom residue distance (Å) B Occ
F:F1005

b:141.0
occ:1.00
 F2 F:AF31005 0.0 141.0 1.0
AL F:AF31005 1.8 141.0 1.0
OE1 F:GLN404 2.2 136.6 1.0
O1B F:ADP1003 3.0 150.4 1.0
F1 F:AF31005 3.1 141.0 1.0
F3 F:AF31005 3.1 141.0 1.0
CB F:PRO284 3.3 143.5 1.0
CA F:PRO284 3.3 143.5 1.0
CD F:GLN404 3.3 136.6 1.0
CE F:LYS288 4.0 140.3 1.0
PB F:ADP1003 4.0 150.4 1.0
NZ F:LYS288 4.1 140.3 1.0
CG F:GLN404 4.1 136.6 1.0
O3B F:ADP1003 4.2 150.4 1.0
N F:PRO284 4.2 143.5 1.0
NH2 F:ARG567 4.2 150.1 1.0
NE2 F:GLN404 4.2 136.6 1.0
N F:GLY285 4.3 147.7 1.0
C F:PRO284 4.3 143.5 1.0
CG F:PRO284 4.6 143.5 1.0
O2B F:ADP1003 4.6 150.4 1.0
OE1 F:GLU375 4.6 130.7 1.0
CG F:GLN537 4.7 143.0 1.0
MG F:MG1004 4.7 121.4 1.0
OE2 F:GLU375 4.7 130.7 1.0
CB F:ASP401 4.8 132.7 1.0
CD F:PRO284 4.8 143.5 1.0
C F:PRO283 4.9 142.5 1.0
CZ F:ARG567 4.9 150.1 1.0
O F:PRO283 4.9 142.5 1.0

Fluorine binding site 6 out of 6 in 7kro

Go back to Fluorine Binding Sites List in 7kro
Fluorine binding site 6 out of 6 in the Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - NSP13(2)-Btc


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of Structure of Sars-Cov-2 Backtracked Complex Complex Bound to NSP13 Helicase - NSP13(2)-Btc within 5.0Å range:
probe atom residue distance (Å) B Occ
F:F1005

b:141.0
occ:1.00
 F3 F:AF31005 0.0 141.0 1.0
AL F:AF31005 1.8 141.0 1.0
MG F:MG1004 2.1 121.4 1.0
OE2 F:GLU375 2.3 130.7 1.0
O3B F:ADP1003 2.5 150.4 1.0
PB F:ADP1003 3.1 150.4 1.0
F2 F:AF31005 3.1 141.0 1.0
F1 F:AF31005 3.1 141.0 1.0
CD F:GLU375 3.1 130.7 1.0
O2B F:ADP1003 3.3 150.4 1.0
O1B F:ADP1003 3.5 150.4 1.0
OE1 F:GLU375 3.5 130.7 1.0
OG F:SER289 4.0 138.1 1.0
CA F:GLY538 4.0 149.2 1.0
N F:GLY538 4.2 149.2 1.0
CG F:GLU375 4.3 130.7 1.0
C F:GLN537 4.4 143.0 1.0
O F:GLN537 4.5 143.0 1.0
CE F:LYS288 4.5 140.3 1.0
O3A F:ADP1003 4.6 150.4 1.0
OE1 F:GLN404 4.6 136.6 1.0
OD1 F:ASP374 4.7 125.6 1.0
CG F:GLN537 4.7 143.0 1.0

Reference:

B.Malone, J.Chen, Q.Wang, E.C.Llewellyn, Y.J.Choi, P.D.B.Olinares, X.Cao, C.Hernandez, E.Eng, B.T.Chait, D.E.Shaw, R.Landick, S.A.Darst, E.A.Campbell. Structural Basis For Backtracking By the Sars-Cov-2 Replication-Transcription Complex Proc.Natl.Acad.Sci.Usa 2021.
ISSN: ESSN 1091-6490
Page generated: Sat Jul 10 14:11:09 2021

Last articles

Cl in 6COG
Cl in 6CST
Cl in 6CTW
Cl in 6CTZ
Cl in 6CTT
Cl in 6CSP
Cl in 6CU9
Cl in 6CTX
Cl in 6CTU
Cl in 6CTP
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy