Fluorine in PDB 7kxt: Crystal Structure of Human Eed

The structure of Crystal Structure of Human Eed, PDB code: 7kxt was solved by L.Zhu, A.Dong, D.Du, Y.Liu, C.Luo, C.H.Arrowsmith, A.M.Edwards, J.Min, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.39 / 2.15
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	81.47, 49.94, 105.32, 90, 105.11, 90
R / Rfree (%)	17.8 / 21.5

The binding sites of Fluorine atom in the Crystal Structure of Human Eed (pdb code 7kxt). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Crystal Structure of Human Eed, PDB code: 7kxt:
Jump to Fluorine binding site number: 1; 2;

Fluorine binding site 1 out of 2 in the Crystal Structure of Human Eed


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of Human Eed within 5.0Å range: probe atom residue distance (Å) B Occ A:F501 b:57.7 occ:1.00 F1 A:XB7501 0.0 57.7 1.0 C24 A:XB7501 1.4 65.7 1.0 C23 A:XB7501 2.3 57.6 1.0 C25 A:XB7501 2.3 69.0 1.0 CZ A:PHE356 3.2 42.0 1.0 NE2 A:HIS397 3.4 49.8 0.6 C22 A:XB7501 3.6 58.5 1.0 C26 A:XB7501 3.6 61.1 1.0 CD2 A:LEU315 3.6 22.8 1.0 CE2 A:PHE356 3.7 34.8 1.0 CD2 A:HIS397 4.0 46.8 0.6 CB A:PRO396 4.1 51.6 0.4 CG A:PRO396 4.1 58.8 0.6 C21 A:XB7501 4.1 60.5 1.0 CE1 A:HIS397 4.1 51.3 0.6 SG A:CYS330 4.2 31.1 1.0 CE1 A:PHE356 4.4 46.2 1.0 CB A:CYS330 4.5 28.7 1.0 CD2 A:LEU391 4.5 38.5 1.0 CA A:PRO396 4.6 55.5 0.4 CB A:PRO396 4.6 54.5 0.6 CD2 A:LEU320 4.8 27.3 1.0 CG A:PRO396 4.8 50.7 0.4 CG A:HIS397 4.9 48.7 0.6 ND1 A:HIS397 4.9 51.9 0.6

Fluorine binding site 2 out of 2 in the Crystal Structure of Human Eed


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Crystal Structure of Human Eed within 5.0Å range: probe atom residue distance (Å) B Occ B:F501 b:60.0 occ:1.00 F1 B:XB7501 0.0 60.0 1.0 C24 B:XB7501 1.4 63.4 1.0 C25 B:XB7501 2.3 60.5 1.0 C23 B:XB7501 2.3 57.9 1.0 CZ B:PHE356 3.1 40.6 1.0 C22 B:XB7501 3.6 53.7 1.0 C26 B:XB7501 3.6 47.6 1.0 CE2 B:PHE356 3.7 34.6 1.0 NE2 B:HIS397 3.7 46.1 0.4 CD2 B:LEU315 3.7 29.8 1.0 C21 B:XB7501 4.1 54.0 1.0 CG B:PRO396 4.1 50.7 0.4 CD2 B:HIS397 4.1 47.1 0.4 CB B:PRO396 4.2 48.0 0.6 CD2 B:LEU391 4.2 37.3 1.0 CE1 B:PHE356 4.2 42.2 1.0 SG B:CYS330 4.4 30.1 1.0 CE1 B:HIS397 4.4 48.0 0.4 CB B:PRO396 4.4 51.0 0.4 CA B:PRO396 4.6 49.8 0.6 CB B:CYS330 4.6 21.0 1.0 CD2 B:LEU320 4.7 32.5 1.0 CG B:PRO396 4.9 48.7 0.6 CG B:HIS397 5.0 47.2 0.4 O B:PRO396 5.0 54.5 0.6

L.Zhu, A.Dong, D.Du, Y.Liu, C.Luo, C.H.Arrowsmith, A.M.Edwards, J.Min. Crystal Structure of Human Eed To Be Published.