Fluorine in PDB 7ky5: Structure of the S. Cerevisiae Phosphatidylcholine Flippase DNF2-LEM3 Complex in the E2P Transition State

Enzymatic activity of Structure of the S. Cerevisiae Phosphatidylcholine Flippase DNF2-LEM3 Complex in the E2P Transition State

All present enzymatic activity of Structure of the S. Cerevisiae Phosphatidylcholine Flippase DNF2-LEM3 Complex in the E2P Transition State:
7.6.2.1;

Other elements in 7ky5:

The structure of Structure of the S. Cerevisiae Phosphatidylcholine Flippase DNF2-LEM3 Complex in the E2P Transition State also contains other interesting chemical elements:

Aluminium (Al) 1 atom
Magnesium (Mg) 1 atom

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Structure of the S. Cerevisiae Phosphatidylcholine Flippase DNF2-LEM3 Complex in the E2P Transition State (pdb code 7ky5). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the Structure of the S. Cerevisiae Phosphatidylcholine Flippase DNF2-LEM3 Complex in the E2P Transition State, PDB code: 7ky5:
Jump to Fluorine binding site number: 1; 2; 3; 4;

Fluorine binding site 1 out of 4 in 7ky5

Go back to Fluorine Binding Sites List in 7ky5
Fluorine binding site 1 out of 4 in the Structure of the S. Cerevisiae Phosphatidylcholine Flippase DNF2-LEM3 Complex in the E2P Transition State


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Structure of the S. Cerevisiae Phosphatidylcholine Flippase DNF2-LEM3 Complex in the E2P Transition State within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F1703

b:193.6
occ:1.00
 F1 A:ALF1703 0.0 193.6 1.0
AL A:ALF1703 1.8 193.6 1.0
F4 A:ALF1703 2.5 193.6 1.0
F3 A:ALF1703 2.5 193.6 1.0
OD1 A:ASP712 2.9 144.4 1.0
C A:THR1032 3.1 162.8 1.0
O A:THR1032 3.3 162.8 1.0
N A:GLY1033 3.3 172.2 1.0
O A:LEU1031 3.5 152.8 1.0
CG A:ASP712 3.6 144.4 1.0
F2 A:ALF1703 3.6 193.6 1.0
CA A:THR1032 3.6 162.8 1.0
CA A:GLY1033 3.7 172.2 1.0
OD2 A:ASP712 3.7 144.4 1.0
N A:THR1032 3.9 162.8 1.0
C A:LEU1031 3.9 152.8 1.0
CG1 A:VAL1148 4.3 166.8 1.0
NZ A:LYS1153 4.6 162.9 1.0
ND2 A:ASN1176 4.7 167.8 1.0
OD1 A:ASP484 4.8 192.2 1.0
CB A:ASP712 4.8 144.4 1.0
CB A:LEU1031 4.9 152.8 1.0
N A:LYS713 5.0 147.6 1.0
O A:VAL1148 5.0 166.8 1.0

Fluorine binding site 2 out of 4 in 7ky5

Go back to Fluorine Binding Sites List in 7ky5
Fluorine binding site 2 out of 4 in the Structure of the S. Cerevisiae Phosphatidylcholine Flippase DNF2-LEM3 Complex in the E2P Transition State


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Structure of the S. Cerevisiae Phosphatidylcholine Flippase DNF2-LEM3 Complex in the E2P Transition State within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F1703

b:193.6
occ:1.00
 F2 A:ALF1703 0.0 193.6 1.0
AL A:ALF1703 1.8 193.6 1.0
F3 A:ALF1703 2.5 193.6 1.0
F4 A:ALF1703 2.5 193.6 1.0
OD1 A:ASP484 2.8 192.2 1.0
CG A:ASP484 3.0 192.2 1.0
O A:LEU483 3.2 176.5 1.0
CA A:ASP484 3.3 192.2 1.0
CB A:ASP484 3.3 192.2 1.0
ND2 A:ASN1176 3.3 167.8 1.0
F1 A:ALF1703 3.6 193.6 1.0
OD2 A:ASP484 3.7 192.2 1.0
CA A:GLY1033 3.9 172.2 1.0
C A:LEU483 4.1 176.5 1.0
N A:ASP484 4.2 192.2 1.0
O A:VAL1148 4.3 166.8 1.0
N A:GLY485 4.3 195.1 1.0
C A:ASP484 4.4 192.2 1.0
NZ A:LYS1153 4.4 162.9 1.0
CG A:ASN1176 4.4 167.8 1.0
N A:GLY1033 4.8 172.2 1.0
CB A:ASN1176 4.8 167.8 1.0
C A:GLY1033 4.8 172.2 1.0

Fluorine binding site 3 out of 4 in 7ky5

Go back to Fluorine Binding Sites List in 7ky5
Fluorine binding site 3 out of 4 in the Structure of the S. Cerevisiae Phosphatidylcholine Flippase DNF2-LEM3 Complex in the E2P Transition State


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Structure of the S. Cerevisiae Phosphatidylcholine Flippase DNF2-LEM3 Complex in the E2P Transition State within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F1703

b:193.6
occ:1.00
 F3 A:ALF1703 0.0 193.6 1.0
AL A:ALF1703 1.8 193.6 1.0
F2 A:ALF1703 2.5 193.6 1.0
F1 A:ALF1703 2.5 193.6 1.0
O A:VAL1148 2.6 166.8 1.0
CG1 A:VAL1148 3.3 166.8 1.0
O A:THR1032 3.4 162.8 1.0
NZ A:LYS1153 3.5 162.9 1.0
CA A:GLY1033 3.5 172.2 1.0
F4 A:ALF1703 3.6 193.6 1.0
C A:VAL1148 3.7 166.8 1.0
C A:THR1032 3.9 162.8 1.0
N A:VAL1148 4.0 166.8 1.0
N A:GLY1033 4.0 172.2 1.0
CA A:VAL1148 4.2 166.8 1.0
CB A:VAL1148 4.4 166.8 1.0
OD1 A:ASP484 4.5 192.2 1.0
CE A:LYS1153 4.6 162.9 1.0
C A:GLY1033 4.8 172.2 1.0
N A:SER1149 4.9 168.7 1.0
CD A:LYS1153 4.9 162.9 1.0
ND2 A:ASN1176 4.9 167.8 1.0
C A:ARG1147 5.0 167.6 1.0
CG A:ASP484 5.0 192.2 1.0

Fluorine binding site 4 out of 4 in 7ky5

Go back to Fluorine Binding Sites List in 7ky5
Fluorine binding site 4 out of 4 in the Structure of the S. Cerevisiae Phosphatidylcholine Flippase DNF2-LEM3 Complex in the E2P Transition State


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Structure of the S. Cerevisiae Phosphatidylcholine Flippase DNF2-LEM3 Complex in the E2P Transition State within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F1703

b:193.6
occ:1.00
 F4 A:ALF1703 0.0 193.6 1.0
AL A:ALF1703 1.8 193.6 1.0
F1 A:ALF1703 2.5 193.6 1.0
F2 A:ALF1703 2.5 193.6 1.0
OD1 A:ASP712 3.0 144.4 1.0
ND2 A:ASN1176 3.0 167.8 1.0
OD1 A:ASP484 3.2 192.2 1.0
OD2 A:ASP712 3.3 144.4 1.0
N A:GLY485 3.4 195.1 1.0
CG A:ASP712 3.5 144.4 1.0
F3 A:ALF1703 3.6 193.6 1.0
CG2 A:THR714 3.7 150.2 1.0
CA A:ASP484 3.7 192.2 1.0
C A:ASP484 3.9 192.2 1.0
CA A:GLY1033 4.0 172.2 1.0
CG A:ASP484 4.1 192.2 1.0
CG A:ASN1176 4.1 167.8 1.0
N A:GLY1033 4.2 172.2 1.0
CA A:GLY485 4.4 195.1 1.0
CB A:ASP484 4.4 192.2 1.0
O A:LEU483 4.5 176.5 1.0
OD1 A:ASN1176 4.5 167.8 1.0
N A:ASP484 4.7 192.2 1.0
C A:THR1032 4.7 162.8 1.0
N A:LYS713 4.9 147.6 1.0
N A:THR714 4.9 150.2 1.0
C A:LEU483 5.0 176.5 1.0

Reference:

L.Bai, Q.You, B.K.Jain, H.D.Duan, A.Kovach, T.R.Graham, H.Li. Transport Mechanism of P4 Atpase Phosphatidylcholine Flippases. Elife V. 9 2020.
ISSN: ESSN 2050-084X
PubMed: 33320091
DOI: 10.7554/ELIFE.62163
Page generated: Fri Aug 2 08:34:08 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy