Fluorine in PDB 7l4f: Crystal Structure of the DRM2-Cat Dna Complex

All present enzymatic activity of Crystal Structure of the DRM2-Cat Dna Complex:
2.1.1.37;

The structure of Crystal Structure of the DRM2-Cat Dna Complex, PDB code: 7l4f was solved by J.Fang, J.Song, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	85.27 / 2.55
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	172.216, 70.833, 103.735, 90, 98.02, 90
R / Rfree (%)	20.8 / 25

The binding sites of Fluorine atom in the Crystal Structure of the DRM2-Cat Dna Complex (pdb code 7l4f). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Crystal Structure of the DRM2-Cat Dna Complex, PDB code: 7l4f:
Jump to Fluorine binding site number: 1; 2;

Fluorine binding site 1 out of 2 in the Crystal Structure of the DRM2-Cat Dna Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of the DRM2-Cat Dna Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:F10 b:105.0 occ:1.00 F D:C4910 0.0 105.0 1.0 C5 D:C4910 1.3 78.2 1.0 C4 D:C4910 2.3 65.7 1.0 CM5 D:C4910 2.3 73.4 1.0 CB B:CYS587 2.3 63.6 1.0 SG B:CYS587 2.3 83.2 1.0 C6 D:C4910 2.4 75.3 1.0 N B:CYS587 2.5 53.0 1.0 N4 D:C4910 2.7 57.3 1.0 CA B:CYS587 2.9 59.8 1.0 O B:SER585 3.2 66.0 1.0 N3 D:C4910 3.4 53.5 1.0 C B:PRO586 3.4 60.2 1.0 N1 D:C4910 3.4 68.7 1.0 OD1 B:ASN313 3.6 65.4 1.0 C2 D:C4910 3.9 57.2 1.0 CA B:PRO586 3.9 61.1 1.0 C B:CYS587 4.2 59.0 1.0 C B:SER585 4.3 59.0 1.0 O B:PRO586 4.3 64.2 1.0 CG B:ASN313 4.4 62.7 1.0 N B:PRO586 4.6 60.5 1.0 C1' D:C4910 4.6 66.8 1.0 ND2 B:ASN313 4.8 64.1 1.0 N B:ASN588 4.8 58.5 1.0 C2' D:C4910 4.9 54.4 1.0 SD B:SAH701 4.9 69.0 1.0 O B:CYS587 4.9 64.0 1.0 O4' D:C4910 5.0 67.7 1.0

Fluorine binding site 2 out of 2 in the Crystal Structure of the DRM2-Cat Dna Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Crystal Structure of the DRM2-Cat Dna Complex within 5.0Å range: probe atom residue distance (Å) B Occ G:F10 b:125.4 occ:1.00 F G:C4910 0.0 125.4 1.0 C5 G:C4910 1.3 106.0 1.0 CM5 G:C4910 2.2 103.1 1.0 C4 G:C4910 2.3 96.5 1.0 SG A:CYS587 2.3 121.4 1.0 C6 G:C4910 2.4 106.0 1.0 CB A:CYS587 2.5 110.8 1.0 N4 G:C4910 2.6 89.1 1.0 N A:CYS587 3.1 94.0 1.0 OD1 A:ASN313 3.2 96.5 1.0 CA A:CYS587 3.3 96.8 1.0 N3 G:C4910 3.4 99.4 1.0 N1 G:C4910 3.5 101.9 1.0 O A:SER585 3.5 85.5 1.0 C A:PRO586 3.6 94.5 1.0 C2 G:C4910 3.9 105.8 1.0 CG A:ASN313 4.1 91.3 1.0 CA A:PRO586 4.2 89.2 1.0 O A:PRO586 4.3 93.7 1.0 C A:CYS587 4.5 93.4 1.0 ND2 A:ASN313 4.6 86.7 1.0 C A:SER585 4.6 82.7 1.0 OD1 A:ASN480 4.6 109.4 1.0 C1' G:C4910 4.7 106.1 1.0 N A:PRO586 4.9 81.8 1.0 N A:VAL314 4.9 94.3 1.0 C2' G:C4910 5.0 101.2 1.0

J.Fang, S.M.Leichter, J.Jiang, M.Biswal, J.Lu, Z.M.Zhang, W.Ren, J.Zhai, Q.Cui, X.Zhong, J.Song. Substrate Deformation Regulates DRM2-Mediated Dna Methylation in Plants. Sci Adv V. 7 2021.
ISSN: ESSN 2375-2548
PubMed: 34078593
DOI: 10.1126/SCIADV.ABD9224