Fluorine in PDB 7l4m: Crystal Structure of the DRM2-Cct Dna Complex

All present enzymatic activity of Crystal Structure of the DRM2-Cct Dna Complex:
2.1.1.37;

The structure of Crystal Structure of the DRM2-Cct Dna Complex, PDB code: 7l4m was solved by J.Fang, J.Song, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.06 / 2.81
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	171.924, 70.981, 104.087, 90, 97.9, 90
R / Rfree (%)	21.4 / 26.3

The binding sites of Fluorine atom in the Crystal Structure of the DRM2-Cct Dna Complex (pdb code 7l4m). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Crystal Structure of the DRM2-Cct Dna Complex, PDB code: 7l4m:
Jump to Fluorine binding site number: 1; 2;

Fluorine binding site 1 out of 2 in the Crystal Structure of the DRM2-Cct Dna Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of the DRM2-Cct Dna Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:F10 b:98.6 occ:1.00 F D:C4910 0.0 98.6 1.0 C5 D:C4910 1.3 83.1 1.0 CM5 D:C4910 2.3 78.8 1.0 SG B:CYS587 2.3 90.3 1.0 C4 D:C4910 2.3 74.4 1.0 C6 D:C4910 2.3 69.6 1.0 CB B:CYS587 2.4 48.5 1.0 N4 D:C4910 2.8 65.1 1.0 N B:CYS587 3.0 71.8 1.0 O B:SER585 3.2 67.0 1.0 CA B:CYS587 3.3 52.8 1.0 OD1 B:ASN313 3.4 47.4 1.0 N3 D:C4910 3.4 78.0 1.0 N1 D:C4910 3.5 43.6 1.0 C B:PRO586 3.7 66.5 1.0 C2 D:C4910 3.9 49.4 1.0 CA B:PRO586 4.2 52.6 1.0 C B:SER585 4.3 48.5 1.0 CG B:ASN313 4.3 55.7 1.0 O B:PRO586 4.4 67.3 1.0 C B:CYS587 4.4 50.6 1.0 C1' D:C4910 4.7 50.9 1.0 N B:PRO586 4.7 46.6 1.0 N B:VAL314 4.9 36.7 1.0 OD1 B:ASN480 4.9 70.5 1.0 ND2 B:ASN313 4.9 48.3 1.0 CA B:ASN313 5.0 51.9 1.0 O B:CYS587 5.0 68.1 1.0 CG1 B:VAL314 5.0 71.0 1.0

Fluorine binding site 2 out of 2 in the Crystal Structure of the DRM2-Cct Dna Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Crystal Structure of the DRM2-Cct Dna Complex within 5.0Å range: probe atom residue distance (Å) B Occ G:F10 b:118.1 occ:1.00 F G:C4910 0.0 118.1 1.0 C5 G:C4910 1.3 94.8 1.0 SG A:CYS587 2.3 188.0 1.0 CM5 G:C4910 2.3 222.6 1.0 C4 G:C4910 2.3 98.6 1.0 C6 G:C4910 2.3 77.6 1.0 CB A:CYS587 2.5 82.9 1.0 N4 G:C4910 2.8 119.6 1.0 N A:CYS587 3.0 83.2 1.0 O A:SER585 3.0 92.1 1.0 CA A:CYS587 3.3 83.2 1.0 OD1 A:ASN313 3.3 92.8 1.0 N3 G:C4910 3.5 90.6 1.0 N1 G:C4910 3.5 74.5 1.0 C A:PRO586 3.6 84.1 1.0 C2 G:C4910 3.9 81.8 1.0 CA A:PRO586 4.1 82.0 1.0 C A:SER585 4.1 86.7 1.0 CG A:ASN313 4.3 95.1 1.0 O A:PRO586 4.4 81.6 1.0 C A:CYS587 4.5 90.1 1.0 N A:PRO586 4.6 86.1 1.0 C1' G:C4910 4.7 81.7 1.0 N A:VAL314 4.9 88.5 1.0 ND2 A:ASN313 5.0 91.4 1.0 O4' G:C4910 5.0 89.4 1.0 CA A:ASN313 5.0 95.1 1.0

J.Fang, S.M.Leichter, J.Jiang, M.Biswal, J.Lu, Z.M.Zhang, W.Ren, J.Zhai, Q.Cui, X.Zhong, J.Song. Substrate Deformation Regulates DRM2-Mediated Dna Methylation in Plants. Sci Adv V. 7 2021.
ISSN: ESSN 2375-2548
PubMed: 34078593
DOI: 10.1126/SCIADV.ABD9224