Fluorine in PDB 7l69: Crystal Structure of Human Polymerase Eta Complexed with Syn N7- Benzylguanine

All present enzymatic activity of Crystal Structure of Human Polymerase Eta Complexed with Syn N7- Benzylguanine:
2.7.7.7;

The structure of Crystal Structure of Human Polymerase Eta Complexed with Syn N7- Benzylguanine, PDB code: 7l69 was solved by H.Jung, S.Lee, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.50 / 1.91
Space group	P 61
Cell size a, b, c (Å), α, β, γ (°)	98.994, 98.994, 81.886, 90, 90, 120
R / Rfree (%)	18.7 / 22.4

The binding sites of Fluorine atom in the Crystal Structure of Human Polymerase Eta Complexed with Syn N7- Benzylguanine (pdb code 7l69). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of Human Polymerase Eta Complexed with Syn N7- Benzylguanine, PDB code: 7l69:

Fluorine binding site 1 out of 1 in the Crystal Structure of Human Polymerase Eta Complexed with Syn N7- Benzylguanine


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of Human Polymerase Eta Complexed with Syn N7- Benzylguanine within 5.0Å range: probe atom residue distance (Å) B Occ T:F4 b:61.6 occ:1.00 F1' T:7BG4 0.0 61.6 1.0 C2' T:7BG4 1.3 50.5 1.0 C1' T:7BG4 2.1 49.5 1.0 C3' T:7BG4 2.3 49.4 1.0 O4' T:7BG4 2.3 53.8 1.0 N9 T:7BG4 2.8 53.1 1.0 C4' T:7BG4 2.9 54.8 1.0 N3 T:7BG4 3.0 49.5 1.0 C4 T:7BG4 3.1 54.2 1.0 O3' T:7BG4 3.5 43.9 1.0 C5 T:DC5 3.5 49.7 1.0 C6 T:DC5 3.6 46.3 1.0 ND2 A:ASN324 3.8 42.6 1.0 C5' T:7BG4 3.9 61.4 1.0 C8 T:7BG4 4.0 52.2 1.0 O5' T:DC5 4.2 42.2 1.0 C2 T:7BG4 4.3 55.7 1.0 OP2 T:DC5 4.3 40.4 1.0 P T:DC5 4.3 40.4 1.0 N1 T:DC5 4.4 46.3 1.0 C4 T:DC5 4.4 53.5 1.0 C5 T:7BG4 4.4 54.0 1.0 O5' T:7BG4 4.4 73.4 1.0 OP2 T:7BG4 4.6 71.3 1.0 O4' T:DC5 4.6 45.0 1.0 N2 T:7BG4 4.8 60.0 1.0 CG A:ASN324 4.8 43.1 1.0 N7 T:7BG4 4.8 55.7 1.0

H.Jung, S.Lee. Crystal Structure of Human Polymerase Eta Complexed with Syn N7-Benzylguanine To Be Published.