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Fluorine in PDB 7l72: Crystal Structure of the Second Bromodomain (BD2) of Human BRD3 Bound to RO3280Protein crystallography data
The structure of Crystal Structure of the Second Bromodomain (BD2) of Human BRD3 Bound to RO3280, PDB code: 7l72
was solved by
M.R.Karim,
M.Bikowitz,
E.Schonbrunn,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of the Second Bromodomain (BD2) of Human BRD3 Bound to RO3280
(pdb code 7l72). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Crystal Structure of the Second Bromodomain (BD2) of Human BRD3 Bound to RO3280, PDB code: 7l72: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 7l72Go back to Fluorine Binding Sites List in 7l72
Fluorine binding site 1 out
of 2 in the Crystal Structure of the Second Bromodomain (BD2) of Human BRD3 Bound to RO3280
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 7l72Go back to Fluorine Binding Sites List in 7l72
Fluorine binding site 2 out
of 2 in the Crystal Structure of the Second Bromodomain (BD2) of Human BRD3 Bound to RO3280
Mono view Stereo pair view
Reference:
R.M.Karim,
M.J.Bikowitz,
A.Chan,
J.Y.Zhu,
D.Grassie,
A.Becker,
N.Berndt,
S.Gunawan,
N.J.Lawrence,
E.Schonbrunn.
Differential Bet Bromodomain Inhibition By Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors. J.Med.Chem. 2021.
Page generated: Thu Nov 25 09:13:14 2021
ISSN: ISSN 0022-2623 PubMed: 34710325 DOI: 10.1021/ACS.JMEDCHEM.1C01096 |
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