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Fluorine in PDB 7lad: Clobetasol Propionate Bound to CYP3A5Enzymatic activity of Clobetasol Propionate Bound to CYP3A5
All present enzymatic activity of Clobetasol Propionate Bound to CYP3A5:
1.14.14.1; Protein crystallography data
The structure of Clobetasol Propionate Bound to CYP3A5, PDB code: 7lad
was solved by
C.D.Buchman,
D.Miller,
J.Wang,
S.Jayaraman,
T.Chen,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7lad:
The structure of Clobetasol Propionate Bound to CYP3A5 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Clobetasol Propionate Bound to CYP3A5
(pdb code 7lad). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Clobetasol Propionate Bound to CYP3A5, PDB code: 7lad: Fluorine binding site 1 out of 1 in 7ladGo back to Fluorine Binding Sites List in 7lad
Fluorine binding site 1 out
of 1 in the Clobetasol Propionate Bound to CYP3A5
Mono view Stereo pair view
Reference:
J.Wang,
C.D.Buchman,
J.Seetharaman,
D.J.Miller,
A.D.Huber,
J.Wu,
S.C.Chai,
E.Garcia-Maldonado,
W.C.Wright,
J.Chenge,
T.Chen.
Unraveling the Structural Basis of Selective Inhibition of Human Cytochrome P450 3A5. J.Am.Chem.Soc. 2021.
Page generated: Fri Nov 5 13:13:24 2021
ISSN: ESSN 1520-5126 PubMed: 34648292 DOI: 10.1021/JACS.1C07066 |
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