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Fluorine in PDB 7lco: Improved Feline Drugs As Sars-Cov-2 Mpro Inhibitors: Structure- Activity Studies & Micellar Solubilization For Enhanced BioavailabilityEnzymatic activity of Improved Feline Drugs As Sars-Cov-2 Mpro Inhibitors: Structure- Activity Studies & Micellar Solubilization For Enhanced Bioavailability
All present enzymatic activity of Improved Feline Drugs As Sars-Cov-2 Mpro Inhibitors: Structure- Activity Studies & Micellar Solubilization For Enhanced Bioavailability:
3.4.22.69; Protein crystallography data
The structure of Improved Feline Drugs As Sars-Cov-2 Mpro Inhibitors: Structure- Activity Studies & Micellar Solubilization For Enhanced Bioavailability, PDB code: 7lco
was solved by
M.B.Khan,
J.Lu,
E.Arutyunova,
H.S.Young,
M.J.Lemieux,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Improved Feline Drugs As Sars-Cov-2 Mpro Inhibitors: Structure- Activity Studies & Micellar Solubilization For Enhanced Bioavailability
(pdb code 7lco). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Improved Feline Drugs As Sars-Cov-2 Mpro Inhibitors: Structure- Activity Studies & Micellar Solubilization For Enhanced Bioavailability, PDB code: 7lco: Fluorine binding site 1 out of 1 in 7lcoGo back to Fluorine Binding Sites List in 7lco
Fluorine binding site 1 out
of 1 in the Improved Feline Drugs As Sars-Cov-2 Mpro Inhibitors: Structure- Activity Studies & Micellar Solubilization For Enhanced Bioavailability
Mono view Stereo pair view
Reference:
W.Vuong,
C.Fischer,
M.B.Khan,
M.J.Van Belkum,
T.Lamer,
K.D.Willoughby,
J.Lu,
E.Arutyunova,
M.A.Joyce,
H.A.Saffran,
J.A.Shields,
H.S.Young,
J.A.Nieman,
D.L.Tyrrell,
M.J.Lemieux,
J.C.Vederas.
Improved Sars-Cov-2 M Pro Inhibitors Based on Feline Antiviral Drug GC376: Structural Enhancements, Increased Solubility, and Micellar Studies. Eur.J.Med.Chem. V. 222 13584 2021.
Page generated: Sat Jul 10 14:17:41 2021
ISSN: ISSN 0223-5234 PubMed: 34118724 DOI: 10.1016/J.EJMECH.2021.113584 |
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