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Fluorine in PDB 7lzd: Crystal Structure of SETD2 Bound to Compound 35Enzymatic activity of Crystal Structure of SETD2 Bound to Compound 35
All present enzymatic activity of Crystal Structure of SETD2 Bound to Compound 35:
2.1.1.359; Protein crystallography data
The structure of Crystal Structure of SETD2 Bound to Compound 35, PDB code: 7lzd
was solved by
N.A.Farrow,
P.Boriack-Sjodin,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7lzd:
The structure of Crystal Structure of SETD2 Bound to Compound 35 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of SETD2 Bound to Compound 35
(pdb code 7lzd). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of SETD2 Bound to Compound 35, PDB code: 7lzd: Fluorine binding site 1 out of 1 in 7lzdGo back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Crystal Structure of SETD2 Bound to Compound 35
![]() Mono view ![]() Stereo pair view
Reference:
J.W.Lampe,
J.S.Alford,
P.A.Boriak-Sjodin,
D.Brach,
K.Cosmopoulos,
K.W.Duncan,
S.T.Eckley,
M.A.Foley,
D.M.Harvey,
V.Motwani,
M.J.Munchhof,
A.Raimondi,
T.V.Riera,
C.Tang,
M.J.Thomenius,
J.Totman,
N.A.Farrow.
Discovery of A First-in-Class Inhibitor of the Histone Methyltransferase SETD2 Suitable For Preclinical Studies Acs Med.Chem.Lett. 2021.
Page generated: Fri Sep 24 13:28:13 2021
ISSN: ISSN 1948-5875 DOI: 10.1021/ACSMEDCHEMLETT.1C00272 |
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