Fluorine in PDB 7m2n: Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15

Enzymatic activity of Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15

All present enzymatic activity of Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15:
1.1.1.27;

Protein crystallography data

The structure of Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15, PDB code: 7m2n was solved by R.Gumpena, J.Ding, D.A.Powell, W.T.Lowther, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 48.89 / 2.50
Space group I 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 83.93, 131.05, 215.518, 90, 99.3, 90
R / Rfree (%) 20.9 / 25.8

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15 (pdb code 7m2n). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 10 binding sites of Fluorine where determined in the Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15, PDB code: 7m2n:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Fluorine binding site 1 out of 10 in 7m2n

Go back to Fluorine Binding Sites List in 7m2n
Fluorine binding site 1 out of 10 in the Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F420

b:55.5
occ:0.50
 F31 A:YOJ420 0.0 55.5 0.5
F31 A:YOJ420 0.3 44.9 0.5
C30 A:YOJ420 1.4 51.9 0.5
C30 A:YOJ420 1.6 42.6 0.5
C32 A:YOJ420 2.4 54.6 0.5
C29 A:YOJ420 2.4 48.8 0.5
C32 A:YOJ420 2.5 45.6 0.5
C29 A:YOJ420 2.6 39.8 0.5
C34 A:YOJ420 2.7 52.2 0.5
C33 A:YOJ420 2.8 59.2 0.5
C34 A:YOJ420 2.8 59.5 0.5
C33 A:YOJ420 2.8 50.2 0.5
CD2 A:LEU108 3.5 64.6 1.0
C48 A:YOJ420 3.7 51.5 0.5
C28 A:YOJ420 3.7 46.5 0.5
C48 A:YOJ420 3.8 42.4 0.5
C35 A:YOJ420 3.8 55.9 0.5
O A:ARG105 3.9 70.5 1.0
C28 A:YOJ420 3.9 38.1 0.5
CG A:LEU108 3.9 63.9 1.0
C35 A:YOJ420 4.0 62.7 0.5
C47 A:YOJ420 4.0 62.8 0.5
CB A:LEU108 4.0 56.8 1.0
C47 A:YOJ420 4.0 54.7 0.5
CG A:ARG105 4.2 91.8 1.0
C27 A:YOJ420 4.2 46.5 0.5
CG2 A:VAL109 4.2 48.5 1.0
CB A:ARG105 4.3 92.3 1.0
C27 A:YOJ420 4.3 38.0 0.5
CD A:PRO138 4.4 31.6 1.0
CA A:ARG105 4.5 83.6 1.0
C A:ARG105 4.6 74.7 1.0
N A:VAL109 4.7 45.7 1.0
C36 A:YOJ420 4.8 58.6 0.5
CD A:ARG105 4.9 90.6 1.0
C46 A:YOJ420 4.9 64.0 0.5
C46 A:YOJ420 4.9 58.6 0.5
C36 A:YOJ420 4.9 64.3 0.5

Fluorine binding site 2 out of 10 in 7m2n

Go back to Fluorine Binding Sites List in 7m2n
Fluorine binding site 2 out of 10 in the Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F420

b:44.9
occ:0.50
 F31 A:YOJ420 0.0 44.9 0.5
F31 A:YOJ420 0.3 55.5 0.5
C30 A:YOJ420 1.2 51.9 0.5
C30 A:YOJ420 1.4 42.6 0.5
C29 A:YOJ420 2.2 48.8 0.5
C32 A:YOJ420 2.3 54.6 0.5
C32 A:YOJ420 2.4 45.6 0.5
C29 A:YOJ420 2.4 39.8 0.5
C34 A:YOJ420 2.7 52.2 0.5
C33 A:YOJ420 2.8 50.2 0.5
C33 A:YOJ420 2.9 59.2 0.5
C34 A:YOJ420 2.9 59.5 0.5
C28 A:YOJ420 3.4 46.5 0.5
CD2 A:LEU108 3.5 64.6 1.0
C48 A:YOJ420 3.5 51.5 0.5
C48 A:YOJ420 3.7 42.4 0.5
C28 A:YOJ420 3.7 38.1 0.5
CG A:LEU108 3.9 63.9 1.0
C35 A:YOJ420 3.9 55.9 0.5
C27 A:YOJ420 4.0 46.5 0.5
CB A:LEU108 4.1 56.8 1.0
O A:ARG105 4.1 70.5 1.0
C47 A:YOJ420 4.1 54.7 0.5
C47 A:YOJ420 4.1 62.8 0.5
C35 A:YOJ420 4.1 62.7 0.5
C27 A:YOJ420 4.2 38.0 0.5
CD A:PRO138 4.2 31.6 1.0
CG2 A:VAL109 4.2 48.5 1.0
CG A:ARG105 4.4 91.8 1.0
CB A:ARG105 4.6 92.3 1.0
CA A:ARG105 4.8 83.6 1.0
N A:VAL109 4.8 45.7 1.0
CG A:PRO138 4.8 32.3 1.0
C A:ARG105 4.9 74.7 1.0
C36 A:YOJ420 4.9 58.6 0.5
N A:PRO138 4.9 31.9 1.0
C46 A:YOJ420 5.0 58.6 0.5

Fluorine binding site 3 out of 10 in 7m2n

Go back to Fluorine Binding Sites List in 7m2n
Fluorine binding site 3 out of 10 in the Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F420

b:32.2
occ:0.50
 F51 A:YOJ420 0.0 32.2 0.5
F51 A:YOJ420 0.3 23.0 0.5
C50 A:YOJ420 1.3 32.1 0.5
C50 A:YOJ420 1.5 23.4 0.5
C05 A:YOJ420 2.3 33.1 0.5
C05 A:YOJ420 2.3 23.9 0.5
C49 A:YOJ420 2.4 31.8 0.5
C49 A:YOJ420 2.6 24.1 0.5
O04 A:YOJ420 2.7 26.8 0.5
S02 A:YOJ420 2.7 24.0 0.5
O04 A:YOJ420 2.8 37.0 0.5
S02 A:YOJ420 2.8 35.1 0.5
N01 A:YOJ420 3.2 35.5 0.5
N01 A:YOJ420 3.3 23.7 0.5
N A:VAL139 3.3 26.0 1.0
OD2 A:ASP140 3.5 26.5 1.0
OD1 A:ASN137 3.5 29.4 1.0
C06 A:YOJ420 3.6 32.8 0.5
CG1 A:VAL139 3.6 24.3 1.0
C08 A:YOJ420 3.6 32.4 0.5
C06 A:YOJ420 3.7 24.2 0.5
O A:HIS192 3.8 28.3 1.0
CB A:HIS192 3.8 24.5 1.0
N A:ASP140 3.8 26.7 1.0
C08 A:YOJ420 3.8 24.7 0.5
C A:PRO138 3.9 28.8 1.0
CA A:PRO138 4.0 30.0 1.0
O03 A:YOJ420 4.1 23.8 0.5
C07 A:YOJ420 4.1 32.4 0.5
CD2 A:HIS192 4.2 24.8 1.0
CA A:VAL139 4.2 25.5 1.0
C07 A:YOJ420 4.3 23.9 0.5
CB A:PRO138 4.3 33.3 1.0
CG A:ASP140 4.3 26.1 1.0
O03 A:YOJ420 4.3 36.6 0.5
N A:HIS192 4.4 26.4 1.0
CG A:HIS192 4.4 23.8 1.0
CB A:VAL139 4.4 25.0 1.0
CA A:HIS192 4.4 26.4 1.0
C A:HIS192 4.4 28.4 1.0
C A:VAL139 4.5 24.6 1.0
CB A:ASP140 4.6 26.2 1.0
CG A:ASN137 4.7 27.9 1.0
CA A:ASP140 4.8 26.6 1.0
O A:PRO138 4.8 29.2 1.0
C09 A:YOJ420 4.9 33.9 0.5

Fluorine binding site 4 out of 10 in 7m2n

Go back to Fluorine Binding Sites List in 7m2n
Fluorine binding site 4 out of 10 in the Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F420

b:23.0
occ:0.50
 F51 A:YOJ420 0.0 23.0 0.5
F51 A:YOJ420 0.3 32.2 0.5
C50 A:YOJ420 1.2 32.1 0.5
C50 A:YOJ420 1.3 23.4 0.5
C49 A:YOJ420 2.1 31.8 0.5
C05 A:YOJ420 2.3 23.9 0.5
C49 A:YOJ420 2.4 24.1 0.5
C05 A:YOJ420 2.4 33.1 0.5
S02 A:YOJ420 2.9 24.0 0.5
O04 A:YOJ420 2.9 26.8 0.5
S02 A:YOJ420 3.1 35.1 0.5
O04 A:YOJ420 3.1 37.0 0.5
OD1 A:ASN137 3.3 29.4 1.0
N A:VAL139 3.3 26.0 1.0
C08 A:YOJ420 3.4 32.4 0.5
N01 A:YOJ420 3.5 35.5 0.5
N01 A:YOJ420 3.5 23.7 0.5
C06 A:YOJ420 3.6 32.8 0.5
C08 A:YOJ420 3.6 24.7 0.5
C06 A:YOJ420 3.6 24.2 0.5
O A:HIS192 3.6 28.3 1.0
CG1 A:VAL139 3.6 24.3 1.0
CB A:HIS192 3.7 24.5 1.0
OD2 A:ASP140 3.7 26.5 1.0
CD2 A:HIS192 3.9 24.8 1.0
C07 A:YOJ420 4.0 32.4 0.5
C A:PRO138 4.0 28.8 1.0
CA A:PRO138 4.1 30.0 1.0
N A:ASP140 4.1 26.7 1.0
C07 A:YOJ420 4.1 23.9 0.5
CG A:HIS192 4.2 23.8 1.0
O03 A:YOJ420 4.3 23.8 0.5
C A:HIS192 4.3 28.4 1.0
CA A:VAL139 4.3 25.5 1.0
CB A:PRO138 4.3 33.3 1.0
CA A:HIS192 4.3 26.4 1.0
N A:HIS192 4.4 26.4 1.0
CB A:VAL139 4.4 25.0 1.0
CG A:ASN137 4.4 27.9 1.0
O03 A:YOJ420 4.5 36.6 0.5
CG A:ASP140 4.6 26.1 1.0
C09 A:YOJ420 4.7 33.9 0.5
C A:VAL139 4.7 24.6 1.0
C09 A:YOJ420 4.8 27.0 0.5
CB A:ASP140 4.9 26.2 1.0
C10 A:YOJ420 4.9 37.3 0.5
O A:PRO138 5.0 29.2 1.0

Fluorine binding site 5 out of 10 in 7m2n

Go back to Fluorine Binding Sites List in 7m2n
Fluorine binding site 5 out of 10 in the Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F422

b:62.8
occ:1.00
 F31 B:YOJ422 0.0 62.8 1.0
C30 B:YOJ422 1.4 54.4 1.0
C32 B:YOJ422 2.4 46.9 1.0
C29 B:YOJ422 2.4 54.3 1.0
C34 B:YOJ422 2.6 51.7 1.0
C33 B:YOJ422 2.8 48.0 1.0
CD2 B:LEU108 2.8 51.5 1.0
CG B:LEU108 3.1 47.3 1.0
CB B:LEU108 3.5 43.7 1.0
C48 B:YOJ422 3.6 46.6 1.0
C28 B:YOJ422 3.6 48.8 1.0
C35 B:YOJ422 3.9 53.4 1.0
C27 B:YOJ422 4.1 42.9 1.0
C47 B:YOJ422 4.2 49.9 1.0
CD B:PRO138 4.3 32.9 1.0
O B:ARG105 4.3 44.7 1.0
CG2 B:VAL109 4.4 38.3 1.0
N B:VAL109 4.5 33.6 1.0
CD1 B:LEU108 4.6 48.5 1.0
C B:LEU108 4.6 34.5 1.0
CA B:LEU108 4.7 39.3 1.0
O1 B:PEG412 4.8 55.8 1.0
N B:PRO138 5.0 29.0 1.0
CG B:PRO138 5.0 31.7 1.0

Fluorine binding site 6 out of 10 in 7m2n

Go back to Fluorine Binding Sites List in 7m2n
Fluorine binding site 6 out of 10 in the Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F422

b:38.9
occ:1.00
 F51 B:YOJ422 0.0 38.9 1.0
C50 B:YOJ422 1.4 36.5 1.0
C49 B:YOJ422 2.4 35.0 1.0
C05 B:YOJ422 2.4 35.1 1.0
O04 B:YOJ422 3.0 29.5 1.0
S02 B:YOJ422 3.0 34.0 1.0
OD1 B:ASN137 3.2 30.0 1.0
N B:VAL139 3.3 31.4 1.0
N01 B:YOJ422 3.5 32.0 1.0
CG1 B:VAL139 3.6 26.9 1.0
CB B:HIS192 3.6 36.9 1.0
C08 B:YOJ422 3.7 36.6 1.0
O B:HIS192 3.7 35.9 1.0
C06 B:YOJ422 3.7 34.6 1.0
OD2 B:ASP140 3.7 31.8 1.0
CD2 B:HIS192 3.8 34.5 1.0
C B:PRO138 3.9 31.5 1.0
CA B:PRO138 4.0 30.6 1.0
N B:ASP140 4.1 27.2 1.0
CG B:HIS192 4.1 35.0 1.0
C07 B:YOJ422 4.1 38.8 1.0
CA B:VAL139 4.2 27.0 1.0
CB B:PRO138 4.3 31.7 1.0
CA B:HIS192 4.3 38.2 1.0
C B:HIS192 4.3 36.8 1.0
CB B:VAL139 4.3 26.2 1.0
CG B:ASN137 4.4 32.2 1.0
N B:HIS192 4.4 38.9 1.0
O03 B:YOJ422 4.4 38.2 1.0
CG B:ASP140 4.5 31.9 1.0
C B:VAL139 4.7 25.6 1.0
CB B:ASP140 4.8 30.9 1.0
O B:PRO138 4.9 34.7 1.0
C09 B:YOJ422 5.0 36.1 1.0

Fluorine binding site 7 out of 10 in 7m2n

Go back to Fluorine Binding Sites List in 7m2n
Fluorine binding site 7 out of 10 in the Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 7 of Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:F421

b:67.9
occ:1.00
 F31 C:YOJ421 0.0 67.9 1.0
C30 C:YOJ421 1.4 58.4 1.0
C29 C:YOJ421 2.3 54.4 1.0
C32 C:YOJ421 2.4 63.2 1.0
C33 C:YOJ421 2.9 72.9 1.0
C34 C:YOJ421 3.0 76.6 1.0
CD2 C:LEU108 3.5 59.8 1.0
CG C:LEU108 3.6 59.1 1.0
C28 C:YOJ421 3.6 53.3 1.0
C48 C:YOJ421 3.6 55.1 1.0
CB C:LEU108 3.9 54.5 1.0
CG2 C:VAL109 3.9 46.6 1.0
C47 C:YOJ421 4.0 83.5 1.0
CD C:PRO138 4.0 45.9 1.0
O C:ARG105 4.0 69.7 1.0
C27 C:YOJ421 4.1 49.9 1.0
C35 C:YOJ421 4.2 79.2 1.0
N C:VAL109 4.4 44.5 1.0
CG C:PRO138 4.7 44.9 1.0
C C:LEU108 4.8 48.7 1.0
CG C:ARG105 4.8 93.5 1.0
O C:HOH588 4.8 52.1 1.0
N C:PRO138 4.8 44.5 1.0
CA C:VAL109 4.9 46.7 1.0
C C:ARG105 4.9 67.8 1.0
C46 C:YOJ421 4.9 90.1 1.0
CB C:ARG105 5.0 83.1 1.0
CA C:ARG105 5.0 72.8 1.0
CA C:LEU108 5.0 50.8 1.0

Fluorine binding site 8 out of 10 in 7m2n

Go back to Fluorine Binding Sites List in 7m2n
Fluorine binding site 8 out of 10 in the Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 8 of Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:F421

b:33.4
occ:1.00
 F51 C:YOJ421 0.0 33.4 1.0
C50 C:YOJ421 1.4 34.3 1.0
C05 C:YOJ421 2.3 34.4 1.0
C49 C:YOJ421 2.4 35.8 1.0
O04 C:YOJ421 2.8 33.8 1.0
S02 C:YOJ421 2.9 34.5 1.0
N C:VAL139 3.3 40.3 1.0
N01 C:YOJ421 3.4 36.9 1.0
OD1 C:ASN137 3.4 36.1 1.0
OD2 C:ASP140 3.6 36.3 1.0
C06 C:YOJ421 3.6 35.7 1.0
CG1 C:VAL139 3.7 37.6 1.0
C08 C:YOJ421 3.7 35.9 1.0
O C:HIS192 3.7 47.0 1.0
CB C:HIS192 3.8 33.9 1.0
C C:PRO138 3.9 42.0 1.0
N C:ASP140 3.9 34.2 1.0
CA C:PRO138 4.0 43.5 1.0
C07 C:YOJ421 4.1 35.8 1.0
CD2 C:HIS192 4.1 35.4 1.0
O03 C:YOJ421 4.2 37.8 1.0
CB C:PRO138 4.2 45.2 1.0
CA C:VAL139 4.3 35.9 1.0
CG C:HIS192 4.3 36.6 1.0
CG C:ASP140 4.4 36.0 1.0
N C:HIS192 4.4 37.2 1.0
C C:HIS192 4.4 38.9 1.0
CA C:HIS192 4.4 36.4 1.0
CB C:VAL139 4.4 36.2 1.0
CG C:ASN137 4.5 40.9 1.0
C C:VAL139 4.6 33.3 1.0
CB C:ASP140 4.7 34.3 1.0
O C:PRO138 4.8 45.9 1.0
CA C:ASP140 4.9 35.4 1.0

Fluorine binding site 9 out of 10 in 7m2n

Go back to Fluorine Binding Sites List in 7m2n
Fluorine binding site 9 out of 10 in the Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 9 of Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15 within 5.0Å range:
probe atom residue distance (Å) B Occ
D:F421

b:55.3
occ:1.00
 F31 D:YOJ421 0.0 55.3 1.0
C30 D:YOJ421 1.4 56.1 1.0
C29 D:YOJ421 2.3 52.7 1.0
C32 D:YOJ421 2.5 58.8 1.0
C33 D:YOJ421 3.0 65.4 1.0
C47 D:YOJ421 3.0 66.7 1.0
CD2 D:LEU108 3.3 54.6 1.0
CG D:LEU108 3.5 51.4 1.0
C28 D:YOJ421 3.6 53.2 1.0
C48 D:YOJ421 3.7 51.3 1.0
CB D:LEU108 3.8 51.1 1.0
CG2 D:VAL109 3.8 39.2 1.0
O D:ARG105 3.9 61.0 1.0
CD D:PRO138 4.1 39.4 1.0
C46 D:YOJ421 4.2 74.0 1.0
C34 D:YOJ421 4.2 79.5 1.0
C27 D:YOJ421 4.2 50.7 1.0
N D:VAL109 4.2 38.0 1.0
C D:LEU108 4.6 39.3 1.0
O D:HOH610 4.6 42.6 1.0
CA D:VAL109 4.7 38.3 1.0
CA D:LEU108 4.8 45.6 1.0
N D:PRO138 4.8 34.3 1.0
CG D:PRO138 4.8 37.7 1.0
C D:ARG105 4.9 59.8 1.0
CD1 D:LEU108 4.9 51.3 1.0
O D:ASN137 4.9 36.0 1.0
CB D:VAL109 4.9 39.9 1.0
CA D:ARG105 4.9 62.0 1.0

Fluorine binding site 10 out of 10 in 7m2n

Go back to Fluorine Binding Sites List in 7m2n
Fluorine binding site 10 out of 10 in the Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 10 of Crystal Structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15 within 5.0Å range:
probe atom residue distance (Å) B Occ
D:F421

b:39.0
occ:1.00
 F51 D:YOJ421 0.0 39.0 1.0
C50 D:YOJ421 1.3 40.0 1.0
C49 D:YOJ421 2.3 39.4 1.0
C05 D:YOJ421 2.4 38.4 1.0
O04 D:YOJ421 2.8 38.2 1.0
S02 D:YOJ421 3.0 40.9 1.0
N D:VAL139 3.3 31.9 1.0
OD1 D:ASN137 3.3 33.2 1.0
N01 D:YOJ421 3.5 43.7 1.0
C08 D:YOJ421 3.6 38.3 1.0
C06 D:YOJ421 3.7 39.0 1.0
O D:HIS192 3.7 35.5 1.0
CG1 D:VAL139 3.7 29.9 1.0
CB D:HIS192 3.7 37.3 1.0
OD2 D:ASP140 3.8 40.9 1.0
CD2 D:HIS192 3.9 36.6 1.0
C D:PRO138 3.9 32.3 1.0
CA D:PRO138 3.9 34.1 1.0
N D:ASP140 4.1 31.7 1.0
C07 D:YOJ421 4.1 40.8 1.0
CG D:HIS192 4.2 35.8 1.0
CB D:PRO138 4.2 36.5 1.0
CA D:VAL139 4.3 33.0 1.0
C D:HIS192 4.3 35.8 1.0
CA D:HIS192 4.3 38.0 1.0
O03 D:YOJ421 4.4 42.2 1.0
N D:HIS192 4.4 38.9 1.0
CG D:ASN137 4.4 36.0 1.0
CB D:VAL139 4.4 32.0 1.0
CG D:ASP140 4.6 40.8 1.0
C D:VAL139 4.7 31.8 1.0
C09 D:YOJ421 4.8 37.0 1.0
CB D:ASP140 4.9 35.9 1.0
O D:PRO138 4.9 30.0 1.0

Reference:

J.Ding, R.Gumpena, M.O.Boily, A.Caron, O.Chong, J.H.Cox, V.Dumais, S.Gaudreault, A.H.Graff, A.King, J.Knight, R.Oballa, J.Surendradoss, T.Tang, J.Wu, W.T.Lowther, D.A.Powell. Dual Glycolate Oxidase/Lactate Dehydrogenase A Inhibitors For Primary Hyperoxaluria Acs Medicinal Chemistry V. 12 1116 2021LETTERS.
DOI: 10.1021/ACSMEDCHEMLETT.1C00196
Page generated: Sat Aug 21 13:50:23 2021

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy