Fluorine in PDB 7m3f: Asymmetric Activation of the Calcium Sensing Receptor Homodimer

The structure of Asymmetric Activation of the Calcium Sensing Receptor Homodimer also contains other interesting chemical elements:

Calcium

(Ca)

4 atoms

The binding sites of Fluorine atom in the Asymmetric Activation of the Calcium Sensing Receptor Homodimer (pdb code 7m3f). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 6 binding sites of Fluorine where determined in the Asymmetric Activation of the Calcium Sensing Receptor Homodimer, PDB code: 7m3f:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6;

Fluorine binding site 1 out of 6 in the Asymmetric Activation of the Calcium Sensing Receptor Homodimer


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Asymmetric Activation of the Calcium Sensing Receptor Homodimer within 5.0Å range: probe atom residue distance (Å) B Occ A:F905 b:82.0 occ:1.00 F1 A:YP4905 0.0 82.0 1.0 C12 A:YP4905 1.3 82.0 1.0 F3 A:YP4905 2.2 82.0 1.0 F2 A:YP4905 2.2 82.0 1.0 C8 A:YP4905 2.4 82.0 1.0 O A:TRP818 2.5 87.5 1.0 C9 A:YP4905 2.8 82.0 1.0 C A:TRP818 3.5 87.5 1.0 CB A:TRP818 3.6 87.5 1.0 C7 A:YP4905 3.7 82.0 1.0 CD1 A:ILE819 4.0 84.9 1.0 C10 A:YP4905 4.1 82.0 1.0 CA A:TRP818 4.2 87.5 1.0 CD1 A:ILE822 4.3 84.2 1.0 N A:ILE819 4.5 84.9 1.0 CG A:TRP818 4.6 87.5 1.0 CG1 A:ILE822 4.7 84.2 1.0 C6 A:YP4905 4.8 82.0 1.0 CA A:ILE819 4.8 84.9 1.0 CG1 A:ILE819 5.0 84.9 1.0 CE3 A:TRP818 5.0 87.5 1.0 C11 A:YP4905 5.0 82.0 1.0

Fluorine binding site 2 out of 6 in the Asymmetric Activation of the Calcium Sensing Receptor Homodimer


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Asymmetric Activation of the Calcium Sensing Receptor Homodimer within 5.0Å range: probe atom residue distance (Å) B Occ A:F905 b:82.0 occ:1.00 F2 A:YP4905 0.0 82.0 1.0 C12 A:YP4905 1.3 82.0 1.0 F1 A:YP4905 2.2 82.0 1.0 F3 A:YP4905 2.2 82.0 1.0 C8 A:YP4905 2.3 82.0 1.0 C7 A:YP4905 3.0 82.0 1.0 C9 A:YP4905 3.4 82.0 1.0 CG2 A:ILE777 3.6 87.1 1.0 C6 A:YP4905 4.3 82.0 1.0 O A:TRP818 4.6 87.5 1.0 C10 A:YP4905 4.6 82.0 1.0 SG A:CYS781 4.6 88.4 1.0 C11 A:YP4905 4.9 82.0 1.0 CD1 A:ILE777 4.9 87.1 1.0

Fluorine binding site 3 out of 6 in the Asymmetric Activation of the Calcium Sensing Receptor Homodimer


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Asymmetric Activation of the Calcium Sensing Receptor Homodimer within 5.0Å range: probe atom residue distance (Å) B Occ A:F905 b:82.0 occ:1.00 F3 A:YP4905 0.0 82.0 1.0 C12 A:YP4905 1.3 82.0 1.0 F1 A:YP4905 2.2 82.0 1.0 F2 A:YP4905 2.2 82.0 1.0 C8 A:YP4905 2.3 82.0 1.0 C7 A:YP4905 2.9 82.0 1.0 CE2 A:YP4905 3.2 82.0 1.0 C9 A:YP4905 3.5 82.0 1.0 CZ A:YP4905 3.5 82.0 1.0 CG2 A:ILE777 3.8 87.1 1.0 CB A:TRP818 3.9 87.5 1.0 CG A:TRP818 4.1 87.5 1.0 SG A:CYS781 4.1 88.4 1.0 CD2 A:YP4905 4.2 82.0 1.0 O A:TRP818 4.2 87.5 1.0 C6 A:YP4905 4.3 82.0 1.0 CD2 A:TRP818 4.4 87.5 1.0 CE1 A:YP4905 4.6 82.0 1.0 C10 A:YP4905 4.6 82.0 1.0 CD1 A:TRP818 4.6 87.5 1.0 CE3 A:TRP818 4.7 87.5 1.0 C11 A:YP4905 5.0 82.0 1.0 C A:TRP818 5.0 87.5 1.0 CA A:TRP818 5.0 87.5 1.0

Fluorine binding site 4 out of 6 in the Asymmetric Activation of the Calcium Sensing Receptor Homodimer


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Asymmetric Activation of the Calcium Sensing Receptor Homodimer within 5.0Å range: probe atom residue distance (Å) B Occ B:F906 b:83.1 occ:1.00 F1 B:YP4906 0.0 83.1 1.0 C12 B:YP4906 1.3 83.1 1.0 F3 B:YP4906 2.2 83.1 1.0 F2 B:YP4906 2.2 83.1 1.0 C8 B:YP4906 2.3 83.1 1.0 C9 B:YP4906 3.0 83.1 1.0 C7 B:YP4906 3.4 83.1 1.0 CD1 B:LEU770 4.2 92.8 1.0 C10 B:YP4906 4.3 83.1 1.0 CD2 B:LEU770 4.4 92.8 1.0 C6 B:YP4906 4.6 83.1 1.0 CG B:LEU770 4.7 92.8 1.0 CB B:LEU770 4.7 92.8 1.0 C11 B:YP4906 5.0 83.1 1.0

Fluorine binding site 5 out of 6 in the Asymmetric Activation of the Calcium Sensing Receptor Homodimer


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of Asymmetric Activation of the Calcium Sensing Receptor Homodimer within 5.0Å range: probe atom residue distance (Å) B Occ B:F906 b:83.1 occ:1.00 F2 B:YP4906 0.0 83.1 1.0 C12 B:YP4906 1.3 83.1 1.0 F3 B:YP4906 2.2 83.1 1.0 F1 B:YP4906 2.2 83.1 1.0 C8 B:YP4906 2.3 83.1 1.0 CD2 B:LEU770 2.6 92.8 1.0 C9 B:YP4906 2.9 83.1 1.0 CG B:LEU770 3.4 92.8 1.0 CB B:LEU770 3.4 92.8 1.0 C7 B:YP4906 3.5 83.1 1.0 CD2 B:LEU773 3.6 89.4 1.0 CD1 B:LEU770 3.6 92.8 1.0 CA B:LEU770 3.9 92.8 1.0 O B:LEU770 4.2 92.8 1.0 CG B:LEU773 4.2 89.4 1.0 C10 B:YP4906 4.2 83.1 1.0 CB B:LEU773 4.2 89.4 1.0 C B:LEU770 4.6 92.8 1.0 C6 B:YP4906 4.7 83.1 1.0 C11 B:YP4906 4.9 83.1 1.0

Fluorine binding site 6 out of 6 in the Asymmetric Activation of the Calcium Sensing Receptor Homodimer


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of Asymmetric Activation of the Calcium Sensing Receptor Homodimer within 5.0Å range: probe atom residue distance (Å) B Occ B:F906 b:83.1 occ:1.00 F3 B:YP4906 0.0 83.1 1.0 C12 B:YP4906 1.3 83.1 1.0 F2 B:YP4906 2.2 83.1 1.0 F1 B:YP4906 2.2 83.1 1.0 C8 B:YP4906 2.4 83.1 1.0 C7 B:YP4906 2.8 83.1 1.0 C9 B:YP4906 3.7 83.1 1.0 CD2 B:LEU773 3.9 89.4 1.0 CG B:LEU773 3.9 89.4 1.0 C6 B:YP4906 4.2 83.1 1.0 CB B:LEU773 4.2 89.4 1.0 N B:GLY774 4.3 89.4 1.0 O B:LEU770 4.4 92.8 1.0 C B:LEU773 4.5 89.4 1.0 CD1 B:ILE777 4.5 87.9 1.0 CA B:GLY774 4.5 89.4 1.0 O B:LEU773 4.7 89.4 1.0 CD2 B:LEU770 4.8 92.8 1.0 C10 B:YP4906 4.8 83.1 1.0 CB B:LEU770 4.9 92.8 1.0

Y.Gao, M.J.Robertson, S.N.Rahman, A.B.Seven, C.Zhang, J.G.Meyerowitz, O.Panova, F.M.Hannan, R.V.Thakker, H.Brauner-Osborne, J.M.Mathiesen, G.Skiniotis. Asymmetric Activation of the Calcium-Sensing Receptor Homodimer Nature 2021.
ISSN: ESSN 1476-4687
DOI: 10.1038/S41586-021-03691-0