Fluorine in PDB 7mge: Structure of C9ORF72:SMCR8:WDR41 in Complex with ARF1
Other elements in 7mge:
The structure of Structure of C9ORF72:SMCR8:WDR41 in Complex with ARF1 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Structure of C9ORF72:SMCR8:WDR41 in Complex with ARF1
(pdb code 7mge). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the
Structure of C9ORF72:SMCR8:WDR41 in Complex with ARF1, PDB code: 7mge:
Jump to Fluorine binding site number:
1;
2;
3;
Fluorine binding site 1 out
of 3 in 7mge
Go back to
Fluorine Binding Sites List in 7mge
Fluorine binding site 1 out
of 3 in the Structure of C9ORF72:SMCR8:WDR41 in Complex with ARF1
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Structure of C9ORF72:SMCR8:WDR41 in Complex with ARF1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:F201
b:130.9
occ:1.00
|
F1
|
E:BEF201
|
0.0
|
130.9
|
1.0
|
BE
|
E:BEF201
|
1.5
|
130.9
|
1.0
|
O
|
E:VAL68
|
2.1
|
133.4
|
1.0
|
OG1
|
E:THR48
|
2.3
|
123.5
|
1.0
|
F3
|
E:BEF201
|
2.5
|
130.9
|
1.0
|
F2
|
E:BEF201
|
2.6
|
130.9
|
1.0
|
OD1
|
E:ASP67
|
2.8
|
136.1
|
1.0
|
CE
|
E:LYS30
|
3.1
|
139.8
|
1.0
|
OD2
|
E:ASP67
|
3.2
|
136.1
|
1.0
|
C
|
E:VAL68
|
3.3
|
133.4
|
1.0
|
OG1
|
E:THR31
|
3.3
|
143.5
|
1.0
|
CG
|
E:ASP67
|
3.4
|
136.1
|
1.0
|
NZ
|
E:LYS30
|
3.4
|
139.8
|
1.0
|
MG
|
E:MG202
|
3.6
|
140.0
|
1.0
|
CB
|
E:THR48
|
3.7
|
123.5
|
1.0
|
CA
|
E:GLY69
|
3.9
|
141.0
|
1.0
|
O1B
|
E:GDP200
|
4.0
|
146.3
|
1.0
|
N
|
E:GLY69
|
4.0
|
141.0
|
1.0
|
O2B
|
E:GDP200
|
4.1
|
146.3
|
1.0
|
N
|
E:THR48
|
4.3
|
123.5
|
1.0
|
N
|
E:VAL68
|
4.3
|
133.4
|
1.0
|
CG2
|
E:THR48
|
4.3
|
123.5
|
1.0
|
CA
|
E:VAL68
|
4.4
|
133.4
|
1.0
|
CD
|
E:LYS30
|
4.5
|
139.8
|
1.0
|
O
|
E:THR48
|
4.5
|
123.5
|
1.0
|
CA
|
E:THR48
|
4.5
|
123.5
|
1.0
|
CG
|
E:LYS30
|
4.6
|
139.8
|
1.0
|
PB
|
E:GDP200
|
4.7
|
146.3
|
1.0
|
CB
|
E:THR31
|
4.7
|
143.5
|
1.0
|
CB
|
E:ASP67
|
4.9
|
136.1
|
1.0
|
C
|
E:THR48
|
4.9
|
123.5
|
1.0
|
C
|
E:ASP67
|
4.9
|
136.1
|
1.0
|
C
|
E:GLY69
|
5.0
|
141.0
|
1.0
|
|
Fluorine binding site 2 out
of 3 in 7mge
Go back to
Fluorine Binding Sites List in 7mge
Fluorine binding site 2 out
of 3 in the Structure of C9ORF72:SMCR8:WDR41 in Complex with ARF1
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Structure of C9ORF72:SMCR8:WDR41 in Complex with ARF1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:F201
b:130.9
occ:1.00
|
F2
|
E:BEF201
|
0.0
|
130.9
|
1.0
|
BE
|
E:BEF201
|
1.6
|
130.9
|
1.0
|
MG
|
E:MG202
|
1.9
|
140.0
|
1.0
|
OG1
|
E:THR31
|
2.1
|
143.5
|
1.0
|
O1B
|
E:GDP200
|
2.3
|
146.3
|
1.0
|
F3
|
E:BEF201
|
2.5
|
130.9
|
1.0
|
F1
|
E:BEF201
|
2.6
|
130.9
|
1.0
|
PB
|
E:GDP200
|
3.2
|
146.3
|
1.0
|
O2A
|
E:GDP200
|
3.2
|
146.3
|
1.0
|
CB
|
E:THR31
|
3.3
|
143.5
|
1.0
|
O3A
|
E:GDP200
|
3.3
|
146.3
|
1.0
|
O2B
|
E:GDP200
|
3.5
|
146.3
|
1.0
|
OG1
|
E:THR48
|
3.6
|
123.5
|
1.0
|
PA
|
E:GDP200
|
3.6
|
146.3
|
1.0
|
NZ
|
E:LYS30
|
3.7
|
139.8
|
1.0
|
O1A
|
E:GDP200
|
3.8
|
146.3
|
1.0
|
OD1
|
E:ASP67
|
4.1
|
136.1
|
1.0
|
N
|
E:THR48
|
4.2
|
123.5
|
1.0
|
N
|
E:THR31
|
4.2
|
143.5
|
1.0
|
CE
|
E:LYS30
|
4.2
|
139.8
|
1.0
|
CG2
|
E:THR31
|
4.2
|
143.5
|
1.0
|
CA
|
E:THR31
|
4.3
|
143.5
|
1.0
|
OD2
|
E:ASP67
|
4.5
|
136.1
|
1.0
|
O3B
|
E:GDP200
|
4.5
|
146.3
|
1.0
|
CG2
|
E:THR48
|
4.5
|
123.5
|
1.0
|
CB
|
E:THR48
|
4.6
|
123.5
|
1.0
|
CG
|
E:LYS30
|
4.6
|
139.8
|
1.0
|
O
|
E:VAL68
|
4.7
|
133.4
|
1.0
|
CA
|
E:PRO47
|
4.7
|
117.4
|
1.0
|
CG
|
E:ASP67
|
4.7
|
136.1
|
1.0
|
C
|
E:PRO47
|
5.0
|
117.4
|
1.0
|
O
|
E:ILE46
|
5.0
|
127.5
|
1.0
|
|
Fluorine binding site 3 out
of 3 in 7mge
Go back to
Fluorine Binding Sites List in 7mge
Fluorine binding site 3 out
of 3 in the Structure of C9ORF72:SMCR8:WDR41 in Complex with ARF1
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Structure of C9ORF72:SMCR8:WDR41 in Complex with ARF1 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:F201
b:130.9
occ:1.00
|
F3
|
E:BEF201
|
0.0
|
130.9
|
1.0
|
BE
|
E:BEF201
|
1.5
|
130.9
|
1.0
|
MG
|
E:MG202
|
1.8
|
140.0
|
1.0
|
NZ
|
E:LYS30
|
2.2
|
139.8
|
1.0
|
O2B
|
E:GDP200
|
2.4
|
146.3
|
1.0
|
F2
|
E:BEF201
|
2.5
|
130.9
|
1.0
|
F1
|
E:BEF201
|
2.5
|
130.9
|
1.0
|
CE
|
E:LYS30
|
3.1
|
139.8
|
1.0
|
PB
|
E:GDP200
|
3.2
|
146.3
|
1.0
|
O1B
|
E:GDP200
|
3.3
|
146.3
|
1.0
|
O3A
|
E:GDP200
|
3.4
|
146.3
|
1.0
|
O
|
E:VAL68
|
4.0
|
133.4
|
1.0
|
OG1
|
E:THR48
|
4.2
|
123.5
|
1.0
|
OG1
|
E:THR31
|
4.3
|
143.5
|
1.0
|
N
|
E:GLY70
|
4.4
|
144.4
|
1.0
|
CD
|
E:LYS30
|
4.4
|
139.8
|
1.0
|
CA
|
E:GLY69
|
4.5
|
141.0
|
1.0
|
PA
|
E:GDP200
|
4.5
|
146.3
|
1.0
|
CG
|
E:LYS30
|
4.6
|
139.8
|
1.0
|
O3B
|
E:GDP200
|
4.6
|
146.3
|
1.0
|
O1A
|
E:GDP200
|
4.7
|
146.3
|
1.0
|
OE1
|
E:GLN71
|
4.7
|
138.5
|
1.0
|
N
|
E:THR48
|
4.8
|
123.5
|
1.0
|
O2A
|
E:GDP200
|
4.8
|
146.3
|
1.0
|
OD1
|
E:ASP67
|
4.9
|
136.1
|
1.0
|
C
|
E:GLY69
|
4.9
|
141.0
|
1.0
|
N
|
E:ALA27
|
4.9
|
144.9
|
1.0
|
O
|
E:LEU25
|
5.0
|
150.9
|
1.0
|
C
|
E:VAL68
|
5.0
|
133.4
|
1.0
|
|
Reference:
M.-Y.Su,
S.A.Fromm,
J.H.Hurley.
Structural Basis For the Arf Gap Activity and Specificity of the C9ORF72 Complex To Be Published.
Page generated: Fri Aug 2 09:29:18 2024
|