Fluorine in PDB 7mt5: Crystal Structure of Tryptophan Synthase in Complex with F9, Cs+, PH7.8 - Alpha Aminoacrylate Form - E(A-A)

Enzymatic activity of Crystal Structure of Tryptophan Synthase in Complex with F9, Cs+, PH7.8 - Alpha Aminoacrylate Form - E(A-A)

All present enzymatic activity of Crystal Structure of Tryptophan Synthase in Complex with F9, Cs+, PH7.8 - Alpha Aminoacrylate Form - E(A-A):
4.2.1.20;

Protein crystallography data

The structure of Crystal Structure of Tryptophan Synthase in Complex with F9, Cs+, PH7.8 - Alpha Aminoacrylate Form - E(A-A), PDB code: 7mt5 was solved by V.Drago, E.Hilario, M.F.Dunn, T.C.Mueser, L.J.Mueller, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 28.25 / 1.50
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 184.189, 59.73, 67.54, 90, 94.63, 90
R / Rfree (%) 17.9 / 20.9

Other elements in 7mt5:

The structure of Crystal Structure of Tryptophan Synthase in Complex with F9, Cs+, PH7.8 - Alpha Aminoacrylate Form - E(A-A) also contains other interesting chemical elements:

Caesium (Cs) 3 atoms

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Crystal Structure of Tryptophan Synthase in Complex with F9, Cs+, PH7.8 - Alpha Aminoacrylate Form - E(A-A) (pdb code 7mt5). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Crystal Structure of Tryptophan Synthase in Complex with F9, Cs+, PH7.8 - Alpha Aminoacrylate Form - E(A-A), PDB code: 7mt5:
Jump to Fluorine binding site number: 1; 2; 3;

Fluorine binding site 1 out of 3 in 7mt5

Go back to Fluorine Binding Sites List in 7mt5
Fluorine binding site 1 out of 3 in the Crystal Structure of Tryptophan Synthase in Complex with F9, Cs+, PH7.8 - Alpha Aminoacrylate Form - E(A-A)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of Tryptophan Synthase in Complex with F9, Cs+, PH7.8 - Alpha Aminoacrylate Form - E(A-A) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F400

b:18.0
occ:1.00
 F9F A:F9F400 0.0 18.0 1.0
C8 A:F9F400 1.3 15.5 1.0
F11 A:F9F400 2.2 20.0 1.0
F10 A:F9F400 2.2 17.9 1.0
O7 A:F9F400 2.3 18.6 1.0
C1 A:F9F400 2.9 15.2 1.0
C6 A:F9F400 2.9 20.0 1.0
O A:HOH724 3.3 17.1 1.0
CD1 A:ILE153 3.6 22.0 1.0
O B:HOH736 3.7 14.7 1.0
CZ A:PHE212 3.8 16.4 1.0
CE2 A:PHE212 4.0 14.3 1.0
CG1 A:ILE153 4.0 18.3 1.0
CD1 A:LEU177 4.1 18.4 1.0
O B:HOH697 4.1 16.6 1.0
C2 A:F9F400 4.1 17.3 1.0
C5 A:F9F400 4.2 17.7 1.0
CG2 A:ILE153 4.3 18.5 1.0
CD2 A:LEU177 4.6 16.6 1.0
CE1 A:PHE212 4.7 14.7 1.0
CB A:ILE153 4.8 15.0 1.0
CG A:LEU177 5.0 21.7 1.0

Fluorine binding site 2 out of 3 in 7mt5

Go back to Fluorine Binding Sites List in 7mt5
Fluorine binding site 2 out of 3 in the Crystal Structure of Tryptophan Synthase in Complex with F9, Cs+, PH7.8 - Alpha Aminoacrylate Form - E(A-A)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Crystal Structure of Tryptophan Synthase in Complex with F9, Cs+, PH7.8 - Alpha Aminoacrylate Form - E(A-A) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F400

b:17.9
occ:1.00
 F10 A:F9F400 0.0 17.9 1.0
C8 A:F9F400 1.3 15.5 1.0
F11 A:F9F400 2.2 20.0 1.0
F9F A:F9F400 2.2 18.0 1.0
O7 A:F9F400 2.3 18.6 1.0
C1 A:F9F400 2.9 15.2 1.0
C6 A:F9F400 3.0 20.0 1.0
O B:HOH697 3.3 16.6 1.0
CA A:ALA129 3.4 15.7 1.0
CD2 A:LEU127 3.4 14.7 1.0
CD1 A:ILE153 3.5 22.0 1.0
CB A:ALA129 3.5 15.9 1.0
O A:ALA129 3.5 15.0 1.0
CG1 A:ILE153 3.7 18.3 1.0
C A:ALA129 3.9 13.6 1.0
C2 A:F9F400 4.2 17.3 1.0
C5 A:F9F400 4.3 17.7 1.0
N A:ALA129 4.5 12.3 1.0
O B:HOH736 4.6 14.7 1.0
CG A:LEU127 4.6 13.6 1.0
CD1 A:LEU127 4.7 16.3 1.0
O A:HOH570 4.7 25.2 1.0
O A:HOH549 4.8 22.3 1.0
O A:VAL128 4.9 13.9 1.0
O A:HOH724 5.0 17.1 1.0
CB A:ILE153 5.0 15.0 1.0

Fluorine binding site 3 out of 3 in 7mt5

Go back to Fluorine Binding Sites List in 7mt5
Fluorine binding site 3 out of 3 in the Crystal Structure of Tryptophan Synthase in Complex with F9, Cs+, PH7.8 - Alpha Aminoacrylate Form - E(A-A)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Crystal Structure of Tryptophan Synthase in Complex with F9, Cs+, PH7.8 - Alpha Aminoacrylate Form - E(A-A) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F400

b:20.0
occ:1.00
 F11 A:F9F400 0.0 20.0 1.0
C8 A:F9F400 1.3 15.5 1.0
F9F A:F9F400 2.2 18.0 1.0
F10 A:F9F400 2.2 17.9 1.0
O7 A:F9F400 2.2 18.6 1.0
O B:HOH697 3.2 16.6 1.0
O A:ALA129 3.3 15.0 1.0
O A:HOH724 3.3 17.1 1.0
O B:HOH736 3.4 14.7 1.0
CB B:PRO18 3.5 11.8 1.0
C1 A:F9F400 3.5 15.2 1.0
CB A:ALA59 3.9 16.4 1.0
CG B:PRO18 4.0 16.8 1.0
CB A:ALA129 4.0 15.9 1.0
C A:ALA129 4.1 13.6 1.0
C6 A:F9F400 4.2 20.0 1.0
CA B:PRO18 4.2 13.5 1.0
CA A:ALA129 4.2 15.7 1.0
O A:HOH633 4.2 19.2 1.0
C2 A:F9F400 4.5 17.3 1.0
CZ A:PHE212 4.8 16.4 1.0
CG1 A:ILE153 4.9 18.3 1.0
N B:GLN19 4.9 13.1 1.0
CD1 A:ILE153 5.0 22.0 1.0

Reference:

L.J.Mueller, V.Drago, E.Hilario, M.F.Dunn, T.C.Mueser, L.J.Mueller. N/A N/A.
Page generated: Fri Aug 2 09:48:26 2024

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