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Fluorine in PDB 7o4i: Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Initial Transcription Bubble

Enzymatic activity of Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Initial Transcription Bubble

All present enzymatic activity of Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Initial Transcription Bubble:
2.7.7.6; 3.6.4.12;

Other elements in 7o4i:

The structure of Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Initial Transcription Bubble also contains other interesting chemical elements:

Zinc (Zn) 17 atoms
Iron (Fe) 4 atoms
Magnesium (Mg) 2 atoms

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Initial Transcription Bubble (pdb code 7o4i). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Initial Transcription Bubble, PDB code: 7o4i:
Jump to Fluorine binding site number: 1; 2; 3;

Fluorine binding site 1 out of 3 in 7o4i

Go back to Fluorine Binding Sites List in 7o4i
Fluorine binding site 1 out of 3 in the Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Initial Transcription Bubble


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Initial Transcription Bubble within 5.0Å range:
probe atom residue distance (Å) B Occ
7:F901

b:201.8
occ:1.00
F1 7:BEF901 0.0 201.8 1.0
BE 7:BEF901 1.5 201.8 1.0
MG 7:MG902 2.0 172.6 1.0
F3 7:BEF901 2.6 201.8 1.0
F2 7:BEF901 2.6 201.8 1.0
O1B 7:ADP903 2.7 201.2 1.0
O3B 7:ADP903 2.9 201.2 1.0
PB 7:ADP903 3.3 201.2 1.0
CA 7:SER661 3.4 203.7 1.0
N 7:SER661 4.0 203.7 1.0
CB 7:SER661 4.1 203.7 1.0
OE2 7:GLU489 4.1 205.8 1.0
OG 7:SER661 4.2 203.7 1.0
C 7:SER661 4.2 203.7 1.0
O2B 7:ADP903 4.3 201.2 1.0
O3A 7:ADP903 4.6 201.2 1.0
CE 7:LYS392 4.7 201.8 1.0
NH2 7:ARG692 4.7 199.6 1.0
O1A 7:ADP903 4.7 201.2 1.0
N 7:ILE662 4.8 202.6 1.0
NZ 7:LYS392 4.8 201.8 1.0
OD2 7:ASP488 4.8 206.3 1.0
O 7:SER661 4.9 203.7 1.0
NH2 7:ARG689 4.9 203.3 1.0
NH1 7:ARG692 4.9 199.6 1.0
NH1 7:ARG689 4.9 203.3 1.0

Fluorine binding site 2 out of 3 in 7o4i

Go back to Fluorine Binding Sites List in 7o4i
Fluorine binding site 2 out of 3 in the Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Initial Transcription Bubble


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Initial Transcription Bubble within 5.0Å range:
probe atom residue distance (Å) B Occ
7:F901

b:201.8
occ:1.00
F2 7:BEF901 0.0 201.8 1.0
BE 7:BEF901 1.6 201.8 1.0
F3 7:BEF901 2.6 201.8 1.0
F1 7:BEF901 2.6 201.8 1.0
O1B 7:ADP903 2.7 201.2 1.0
NZ 7:LYS392 3.1 201.8 1.0
SG 7:CYS388 3.4 202.1 1.0
CA 7:CYS388 3.4 202.1 1.0
CB 7:CYS388 3.4 202.1 1.0
PB 7:ADP903 3.5 201.2 1.0
CE 7:LYS392 3.5 201.8 1.0
O2B 7:ADP903 3.6 201.2 1.0
N 7:GLY389 4.0 201.7 1.0
O3B 7:ADP903 4.0 201.2 1.0
NH2 7:ARG689 4.0 203.3 1.0
MG 7:MG902 4.1 172.6 1.0
NH2 7:ARG692 4.2 199.6 1.0
C 7:CYS388 4.2 202.1 1.0
OE2 7:GLU489 4.2 205.8 1.0
N 7:CYS388 4.6 202.1 1.0
OE1 7:GLN685 4.9 204.6 1.0
OG1 7:THR660 4.9 204.8 1.0
CB 7:ALA515 5.0 202.2 1.0
O3A 7:ADP903 5.0 201.2 1.0
N 7:SER661 5.0 203.7 1.0

Fluorine binding site 3 out of 3 in 7o4i

Go back to Fluorine Binding Sites List in 7o4i
Fluorine binding site 3 out of 3 in the Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Initial Transcription Bubble


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Yeast Rna Polymerase II Transcription Pre-Initiation Complex with Initial Transcription Bubble within 5.0Å range:
probe atom residue distance (Å) B Occ
7:F901

b:201.8
occ:1.00
F3 7:BEF901 0.0 201.8 1.0
BE 7:BEF901 1.5 201.8 1.0
F2 7:BEF901 2.6 201.8 1.0
O1B 7:ADP903 2.6 201.2 1.0
NH2 7:ARG692 2.6 199.6 1.0
F1 7:BEF901 2.6 201.8 1.0
NH2 7:ARG689 2.6 203.3 1.0
NH1 7:ARG689 2.9 203.3 1.0
CZ 7:ARG689 3.1 203.3 1.0
CZ 7:ARG692 3.4 199.6 1.0
NH1 7:ARG692 3.6 199.6 1.0
N 7:SER661 3.8 203.7 1.0
CA 7:SER661 4.0 203.7 1.0
PB 7:ADP903 4.0 201.2 1.0
CB 7:CYS388 4.1 202.1 1.0
N 7:GLY389 4.2 201.7 1.0
O 7:ILE662 4.3 202.6 1.0
N 7:ILE662 4.3 202.6 1.0
MG 7:MG902 4.4 172.6 1.0
NE 7:ARG689 4.5 203.3 1.0
C 7:SER661 4.5 203.7 1.0
CA 7:CYS388 4.5 202.1 1.0
O3B 7:ADP903 4.6 201.2 1.0
NE 7:ARG692 4.6 199.6 1.0
SG 7:CYS388 4.6 202.1 1.0
C 7:CYS388 4.7 202.1 1.0
O2B 7:ADP903 4.9 201.2 1.0
C 7:ILE662 4.9 202.6 1.0
O3A 7:ADP903 5.0 201.2 1.0
CA 7:GLY389 5.0 201.7 1.0
C 7:THR660 5.0 204.8 1.0

Reference:

S.Schilbach, S.Aibara, C.Dienemann, F.Grabbe, P.Cramer. Structure of Rna Polymerase II Pre-Initiation Complex at 2.9 Angstrom Defines Initial Dna Opening Cell(Cambridge,Mass.) 2021.
ISSN: ISSN 0092-8674
DOI: 10.1016/J.CELL.2021.05.012
Page generated: Fri Aug 2 10:39:48 2024

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