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Fluorine in PDB 7p2s: Crystal Structure of Schistosoma Mansoni HDAC8 in Complex with A Tricyclic Thieno[3,2-B]Indole Capped Hydroxamate-Based Inhibitor, Chlorine DerivativeProtein crystallography data
The structure of Crystal Structure of Schistosoma Mansoni HDAC8 in Complex with A Tricyclic Thieno[3,2-B]Indole Capped Hydroxamate-Based Inhibitor, Chlorine Derivative, PDB code: 7p2s
was solved by
F.Saccoccia,
S.Gemma,
G.Campiani,
G.Ruberti,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7p2s:
The structure of Crystal Structure of Schistosoma Mansoni HDAC8 in Complex with A Tricyclic Thieno[3,2-B]Indole Capped Hydroxamate-Based Inhibitor, Chlorine Derivative also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Schistosoma Mansoni HDAC8 in Complex with A Tricyclic Thieno[3,2-B]Indole Capped Hydroxamate-Based Inhibitor, Chlorine Derivative
(pdb code 7p2s). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of Schistosoma Mansoni HDAC8 in Complex with A Tricyclic Thieno[3,2-B]Indole Capped Hydroxamate-Based Inhibitor, Chlorine Derivative, PDB code: 7p2s: Fluorine binding site 1 out of 1 in 7p2sGo back to Fluorine Binding Sites List in 7p2s
Fluorine binding site 1 out
of 1 in the Crystal Structure of Schistosoma Mansoni HDAC8 in Complex with A Tricyclic Thieno[3,2-B]Indole Capped Hydroxamate-Based Inhibitor, Chlorine Derivative
Mono view Stereo pair view
Reference:
F.Saccoccia,
L.Pozzetti,
R.Gimmelli,
S.Butini,
A.Guidi,
G.Papoff,
M.Giannaccari,
S.Brogi,
V.Scognamiglio,
S.Gemma,
G.Ruberti,
G.Campiani.
Crystal Structures of Schistosoma Mansoni Histone Deacetylase 8 Reveal A Novel Binding Site For Allosteric Inhibitors. J.Biol.Chem. V. 298 02375 2022.
Page generated: Fri Aug 2 10:54:38 2024
ISSN: ESSN 1083-351X PubMed: 35970392 DOI: 10.1016/J.JBC.2022.102375 |
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