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Fluorine in PDB 7rkw: Naegleria Fowleri CYP51(NFCYP51) Complex with (S)-1-(4-Fluorophenyl)- 2-(1H-Imidazol-1-Yl)Ethyl 3,5-DichlorobenzoateProtein crystallography data
The structure of Naegleria Fowleri CYP51(NFCYP51) Complex with (S)-1-(4-Fluorophenyl)- 2-(1H-Imidazol-1-Yl)Ethyl 3,5-Dichlorobenzoate, PDB code: 7rkw
was solved by
V.Sharma,
L.M.Podust,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7rkw:
The structure of Naegleria Fowleri CYP51(NFCYP51) Complex with (S)-1-(4-Fluorophenyl)- 2-(1H-Imidazol-1-Yl)Ethyl 3,5-Dichlorobenzoate also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Naegleria Fowleri CYP51(NFCYP51) Complex with (S)-1-(4-Fluorophenyl)- 2-(1H-Imidazol-1-Yl)Ethyl 3,5-Dichlorobenzoate
(pdb code 7rkw). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Naegleria Fowleri CYP51(NFCYP51) Complex with (S)-1-(4-Fluorophenyl)- 2-(1H-Imidazol-1-Yl)Ethyl 3,5-Dichlorobenzoate, PDB code: 7rkw: Fluorine binding site 1 out of 1 in 7rkwGo back to Fluorine Binding Sites List in 7rkw
Fluorine binding site 1 out
of 1 in the Naegleria Fowleri CYP51(NFCYP51) Complex with (S)-1-(4-Fluorophenyl)- 2-(1H-Imidazol-1-Yl)Ethyl 3,5-Dichlorobenzoate
Mono view Stereo pair view
Reference:
V.Sharma,
L.M.Podust.
Structure-Aided Approaches to Develop Naegleria Fowleri Specific Brain Permeable CYP51 Inhibitors. To Be Published.
Page generated: Wed Apr 5 00:55:14 2023
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