Fluorine in PDB 7rz5: Structure of the Complex of Lbd-Tmd Part of Ampa Receptor GLUA2 with Auxiliary Subunit Tarp Gamma-5 Bound to Competitive Antagonist Zk 200775

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>>> Page 1 <<< Page 2, Binding sites: 11 - 12;

Binding sites:

The binding sites of Fluorine atom in the Structure of the Complex of Lbd-Tmd Part of Ampa Receptor GLUA2 with Auxiliary Subunit Tarp Gamma-5 Bound to Competitive Antagonist Zk 200775 (pdb code 7rz5). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 12 binding sites of Fluorine where determined in the Structure of the Complex of Lbd-Tmd Part of Ampa Receptor GLUA2 with Auxiliary Subunit Tarp Gamma-5 Bound to Competitive Antagonist Zk 200775, PDB code: 7rz5:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Fluorine binding site 1 out of 12 in the Structure of the Complex of Lbd-Tmd Part of Ampa Receptor GLUA2 with Auxiliary Subunit Tarp Gamma-5 Bound to Competitive Antagonist Zk 200775


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Structure of the Complex of Lbd-Tmd Part of Ampa Receptor GLUA2 with Auxiliary Subunit Tarp Gamma-5 Bound to Competitive Antagonist Zk 200775 within 5.0Å range: probe atom residue distance (Å) B Occ A:F1101 b:41.3 occ:1.00 FAF A:ZK11101 0.0 41.3 1.0 CAZ A:ZK11101 1.4 41.3 1.0 FAG A:ZK11101 2.2 41.3 1.0 FAH A:ZK11101 2.2 41.3 1.0 CAS A:ZK11101 2.3 41.3 1.0 CAR A:ZK11101 3.1 41.3 1.0 NAX A:ZK11101 3.2 41.3 1.0 CAM A:ZK11101 3.2 41.3 1.0 CAJ A:ZK11101 3.3 41.3 1.0 OH A:TYR732 3.6 37.5 1.0 CG A:MET708 3.7 55.9 1.0 CAN A:ZK11101 4.2 41.3 1.0 OG1 A:THR707 4.2 54.6 1.0 CG A:GLU705 4.3 56.3 1.0 CAI A:ZK11101 4.3 41.3 1.0 CE A:MET708 4.4 55.9 1.0 CB A:GLU705 4.5 56.3 1.0 CAK A:ZK11101 4.5 41.3 1.0 CAV A:ZK11101 4.5 41.3 1.0 SD A:MET708 4.6 55.9 1.0 CZ A:TYR732 4.8 37.5 1.0 CB A:MET708 4.9 55.9 1.0 CAW A:ZK11101 4.9 41.3 1.0 CE2 A:TYR405 4.9 48.8 1.0

Fluorine binding site 2 out of 12 in the Structure of the Complex of Lbd-Tmd Part of Ampa Receptor GLUA2 with Auxiliary Subunit Tarp Gamma-5 Bound to Competitive Antagonist Zk 200775


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Structure of the Complex of Lbd-Tmd Part of Ampa Receptor GLUA2 with Auxiliary Subunit Tarp Gamma-5 Bound to Competitive Antagonist Zk 200775 within 5.0Å range: probe atom residue distance (Å) B Occ A:F1101 b:41.3 occ:1.00 FAG A:ZK11101 0.0 41.3 1.0 CAZ A:ZK11101 1.4 41.3 1.0 FAH A:ZK11101 2.2 41.3 1.0 FAF A:ZK11101 2.2 41.3 1.0 CAS A:ZK11101 2.3 41.3 1.0 CAJ A:ZK11101 2.6 41.3 1.0 OH A:TYR732 3.4 37.5 1.0 CB A:PRO478 3.5 40.3 1.0 CAR A:ZK11101 3.6 41.3 1.0 CE2 A:TYR405 3.9 48.8 1.0 CG A:PRO478 3.9 40.3 1.0 CAV A:ZK11101 4.0 41.3 1.0 CZ A:TYR732 4.1 37.5 1.0 OH A:TYR450 4.2 60.1 1.0 CE2 A:TYR732 4.3 37.5 1.0 NAX A:ZK11101 4.3 41.3 1.0 CZ A:TYR405 4.4 48.8 1.0 CD2 A:TYR405 4.5 48.8 1.0 OH A:TYR405 4.5 48.8 1.0 NAP A:ZK11101 4.7 41.3 1.0 CAI A:ZK11101 4.7 41.3 1.0 O A:PRO478 4.7 40.3 1.0 CAW A:ZK11101 4.8 41.3 1.0 CA A:PRO478 4.9 40.3 1.0 CAM A:ZK11101 5.0 41.3 1.0 CAN A:ZK11101 5.0 41.3 1.0

Fluorine binding site 3 out of 12 in the Structure of the Complex of Lbd-Tmd Part of Ampa Receptor GLUA2 with Auxiliary Subunit Tarp Gamma-5 Bound to Competitive Antagonist Zk 200775


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Structure of the Complex of Lbd-Tmd Part of Ampa Receptor GLUA2 with Auxiliary Subunit Tarp Gamma-5 Bound to Competitive Antagonist Zk 200775 within 5.0Å range: probe atom residue distance (Å) B Occ A:F1101 b:41.3 occ:1.00 FAH A:ZK11101 0.0 41.3 1.0 CAZ A:ZK11101 1.4 41.3 1.0 FAG A:ZK11101 2.2 41.3 1.0 FAF A:ZK11101 2.2 41.3 1.0 CAS A:ZK11101 2.4 41.3 1.0 CAR A:ZK11101 3.0 41.3 1.0 NAX A:ZK11101 3.0 41.3 1.0 CAN A:ZK11101 3.2 41.3 1.0 CAJ A:ZK11101 3.4 41.3 1.0 OE1 A:GLU402 3.6 61.2 1.0 CAM A:ZK11101 3.8 41.3 1.0 OH A:TYR450 3.9 60.1 1.0 CD A:GLU402 3.9 61.2 1.0 CG A:GLU402 4.1 61.2 1.0 CAI A:ZK11101 4.3 41.3 1.0 CE A:MET708 4.3 55.9 1.0 CG A:MET708 4.3 55.9 1.0 CAL A:ZK11101 4.4 41.3 1.0 SD A:MET708 4.5 55.9 1.0 CB A:GLU402 4.5 61.2 1.0 CAV A:ZK11101 4.6 41.3 1.0 CE2 A:TYR405 4.6 48.8 1.0 OE2 A:GLU402 4.7 61.2 1.0 CAK A:ZK11101 4.8 41.3 1.0 CAW A:ZK11101 5.0 41.3 1.0 CZ A:TYR450 5.0 60.1 1.0 CD2 A:TYR405 5.0 48.8 1.0

Fluorine binding site 4 out of 12 in the Structure of the Complex of Lbd-Tmd Part of Ampa Receptor GLUA2 with Auxiliary Subunit Tarp Gamma-5 Bound to Competitive Antagonist Zk 200775


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Structure of the Complex of Lbd-Tmd Part of Ampa Receptor GLUA2 with Auxiliary Subunit Tarp Gamma-5 Bound to Competitive Antagonist Zk 200775 within 5.0Å range: probe atom residue distance (Å) B Occ B:F1101 b:24.0 occ:1.00 FAF B:ZK11101 0.0 24.0 1.0 CAZ B:ZK11101 1.4 24.0 1.0 FAG B:ZK11101 2.2 24.0 1.0 FAH B:ZK11101 2.2 24.0 1.0 CAS B:ZK11101 2.4 24.0 1.0 OE1 B:GLU705 2.7 75.7 1.0 CAR B:ZK11101 3.1 24.0 1.0 CAM B:ZK11101 3.3 24.0 1.0 NAX B:ZK11101 3.3 24.0 1.0 CAJ B:ZK11101 3.3 24.0 1.0 OH B:TYR732 3.4 60.2 1.0 CD B:GLU705 3.8 75.7 1.0 CG B:MET708 4.0 75.5 1.0 CAK B:ZK11101 4.2 24.0 1.0 CAN B:ZK11101 4.3 24.0 1.0 OE2 B:GLU705 4.3 75.7 1.0 OG1 B:THR707 4.3 69.5 1.0 CAI B:ZK11101 4.3 24.0 1.0 CAV B:ZK11101 4.5 24.0 1.0 CZ B:TYR732 4.7 60.2 1.0 CE B:MET708 4.7 75.5 1.0 CB B:GLU705 4.8 75.7 1.0 CG B:GLU705 4.8 75.7 1.0 SD B:MET708 4.9 75.5 1.0 CAW B:ZK11101 4.9 24.0 1.0

Fluorine binding site 5 out of 12 in the Structure of the Complex of Lbd-Tmd Part of Ampa Receptor GLUA2 with Auxiliary Subunit Tarp Gamma-5 Bound to Competitive Antagonist Zk 200775


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of Structure of the Complex of Lbd-Tmd Part of Ampa Receptor GLUA2 with Auxiliary Subunit Tarp Gamma-5 Bound to Competitive Antagonist Zk 200775 within 5.0Å range: probe atom residue distance (Å) B Occ B:F1101 b:24.0 occ:1.00 FAG B:ZK11101 0.0 24.0 1.0 CAZ B:ZK11101 1.4 24.0 1.0 FAH B:ZK11101 2.2 24.0 1.0 FAF B:ZK11101 2.2 24.0 1.0 CAS B:ZK11101 2.3 24.0 1.0 CAJ B:ZK11101 2.6 24.0 1.0 OH B:TYR732 3.4 60.2 1.0 CAR B:ZK11101 3.6 24.0 1.0 CE2 B:TYR405 3.8 71.6 1.0 CB B:PRO478 3.8 64.5 1.0 CG B:PRO478 3.8 64.5 1.0 CAV B:ZK11101 4.0 24.0 1.0 OH B:TYR450 4.0 86.3 1.0 CZ B:TYR732 4.1 60.2 1.0 NAX B:ZK11101 4.3 24.0 1.0 CD2 B:TYR405 4.4 71.6 1.0 OE1 B:GLU705 4.4 75.7 1.0 CE2 B:TYR732 4.5 60.2 1.0 O B:PRO478 4.6 64.5 1.0 CZ B:TYR450 4.7 86.3 1.0 CAI B:ZK11101 4.7 24.0 1.0 CZ B:TYR405 4.7 71.6 1.0 NAP B:ZK11101 4.8 24.0 1.0 OH B:TYR405 4.8 71.6 1.0 CAW B:ZK11101 4.9 24.0 1.0 CE1 B:TYR732 4.9 60.2 1.0 CAM B:ZK11101 5.0 24.0 1.0 CG B:GLU402 5.0 84.5 1.0 CE1 B:TYR450 5.0 86.3 1.0

Fluorine binding site 6 out of 12 in the Structure of the Complex of Lbd-Tmd Part of Ampa Receptor GLUA2 with Auxiliary Subunit Tarp Gamma-5 Bound to Competitive Antagonist Zk 200775


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of Structure of the Complex of Lbd-Tmd Part of Ampa Receptor GLUA2 with Auxiliary Subunit Tarp Gamma-5 Bound to Competitive Antagonist Zk 200775 within 5.0Å range: probe atom residue distance (Å) B Occ B:F1101 b:24.0 occ:1.00 FAH B:ZK11101 0.0 24.0 1.0 CAZ B:ZK11101 1.4 24.0 1.0 FAG B:ZK11101 2.2 24.0 1.0 FAF B:ZK11101 2.2 24.0 1.0 CAS B:ZK11101 2.4 24.0 1.0 NAX B:ZK11101 2.9 24.0 1.0 CAR B:ZK11101 2.9 24.0 1.0 CAN B:ZK11101 3.2 24.0 1.0 CAJ B:ZK11101 3.5 24.0 1.0 OH B:TYR450 3.6 86.3 1.0 CAM B:ZK11101 3.7 24.0 1.0 CG B:GLU402 3.8 84.5 1.0 CAL B:ZK11101 4.0 24.0 1.0 CD B:GLU402 4.1 84.5 1.0 CAI B:ZK11101 4.3 24.0 1.0 OE2 B:GLU402 4.3 84.5 1.0 CAK B:ZK11101 4.4 24.0 1.0 CG B:MET708 4.5 75.5 1.0 CE B:MET708 4.5 75.5 1.0 CZ B:TYR450 4.6 86.3 1.0 CAV B:ZK11101 4.7 24.0 1.0 SD B:MET708 4.7 75.5 1.0 OE1 B:GLU402 4.7 84.5 1.0 OAQ B:ZK11101 4.8 24.0 1.0 CE2 B:TYR405 4.9 71.6 1.0 CB B:GLU402 4.9 84.5 1.0 OE1 B:GLU705 4.9 75.7 1.0 CAW B:ZK11101 5.0 24.0 1.0

Fluorine binding site 7 out of 12 in the Structure of the Complex of Lbd-Tmd Part of Ampa Receptor GLUA2 with Auxiliary Subunit Tarp Gamma-5 Bound to Competitive Antagonist Zk 200775


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 7 of Structure of the Complex of Lbd-Tmd Part of Ampa Receptor GLUA2 with Auxiliary Subunit Tarp Gamma-5 Bound to Competitive Antagonist Zk 200775 within 5.0Å range: probe atom residue distance (Å) B Occ C:F1101 b:36.9 occ:1.00 FAF C:ZK11101 0.0 36.9 1.0 CAZ C:ZK11101 1.4 36.9 1.0 FAG C:ZK11101 2.2 36.9 1.0 FAH C:ZK11101 2.2 36.9 1.0 CAS C:ZK11101 2.3 36.9 1.0 CAR C:ZK11101 3.1 36.9 1.0 NAX C:ZK11101 3.2 36.9 1.0 CAM C:ZK11101 3.2 36.9 1.0 CAJ C:ZK11101 3.3 36.9 1.0 OH C:TYR732 3.6 36.7 1.0 CG C:MET708 3.7 55.0 1.0 CAN C:ZK11101 4.2 36.9 1.0 OG1 C:THR707 4.2 53.0 1.0 CG C:GLU705 4.3 55.2 1.0 CAI C:ZK11101 4.3 36.9 1.0 CE C:MET708 4.4 55.0 1.0 CAK C:ZK11101 4.5 36.9 1.0 CB C:GLU705 4.5 55.2 1.0 CAV C:ZK11101 4.5 36.9 1.0 SD C:MET708 4.6 55.0 1.0 CZ C:TYR732 4.8 36.7 1.0 CE2 C:TYR405 4.9 48.1 1.0 CB C:MET708 4.9 55.0 1.0 CAW C:ZK11101 4.9 36.9 1.0

Fluorine binding site 8 out of 12 in the Structure of the Complex of Lbd-Tmd Part of Ampa Receptor GLUA2 with Auxiliary Subunit Tarp Gamma-5 Bound to Competitive Antagonist Zk 200775


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 8 of Structure of the Complex of Lbd-Tmd Part of Ampa Receptor GLUA2 with Auxiliary Subunit Tarp Gamma-5 Bound to Competitive Antagonist Zk 200775 within 5.0Å range: probe atom residue distance (Å) B Occ C:F1101 b:36.9 occ:1.00 FAG C:ZK11101 0.0 36.9 1.0 CAZ C:ZK11101 1.4 36.9 1.0 FAH C:ZK11101 2.2 36.9 1.0 FAF C:ZK11101 2.2 36.9 1.0 CAS C:ZK11101 2.3 36.9 1.0 CAJ C:ZK11101 2.6 36.9 1.0 CB C:PRO478 3.4 38.6 1.0 OH C:TYR732 3.5 36.7 1.0 CAR C:ZK11101 3.6 36.9 1.0 CE2 C:TYR405 3.8 48.1 1.0 CG C:PRO478 3.9 38.6 1.0 CAV C:ZK11101 4.0 36.9 1.0 CZ C:TYR732 4.1 36.7 1.0 OH C:TYR450 4.2 58.7 1.0 CE2 C:TYR732 4.3 36.7 1.0 NAX C:ZK11101 4.3 36.9 1.0 CZ C:TYR405 4.4 48.1 1.0 CD2 C:TYR405 4.4 48.1 1.0 OH C:TYR405 4.5 48.1 1.0 NAP C:ZK11101 4.7 36.9 1.0 O C:PRO478 4.7 38.6 1.0 CAI C:ZK11101 4.7 36.9 1.0 CAW C:ZK11101 4.8 36.9 1.0 CA C:PRO478 4.9 38.6 1.0 CAM C:ZK11101 5.0 36.9 1.0 CAN C:ZK11101 5.0 36.9 1.0

Fluorine binding site 9 out of 12 in the Structure of the Complex of Lbd-Tmd Part of Ampa Receptor GLUA2 with Auxiliary Subunit Tarp Gamma-5 Bound to Competitive Antagonist Zk 200775


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 9 of Structure of the Complex of Lbd-Tmd Part of Ampa Receptor GLUA2 with Auxiliary Subunit Tarp Gamma-5 Bound to Competitive Antagonist Zk 200775 within 5.0Å range: probe atom residue distance (Å) B Occ C:F1101 b:36.9 occ:1.00 FAH C:ZK11101 0.0 36.9 1.0 CAZ C:ZK11101 1.4 36.9 1.0 FAG C:ZK11101 2.2 36.9 1.0 FAF C:ZK11101 2.2 36.9 1.0 CAS C:ZK11101 2.4 36.9 1.0 CAR C:ZK11101 3.0 36.9 1.0 NAX C:ZK11101 3.0 36.9 1.0 CAN C:ZK11101 3.2 36.9 1.0 CAJ C:ZK11101 3.4 36.9 1.0 OE1 C:GLU402 3.6 60.9 1.0 CAM C:ZK11101 3.8 36.9 1.0 OH C:TYR450 3.8 58.7 1.0 CD C:GLU402 3.9 60.9 1.0 CG C:GLU402 4.0 60.9 1.0 CE C:MET708 4.3 55.0 1.0 CAI C:ZK11101 4.3 36.9 1.0 CAL C:ZK11101 4.4 36.9 1.0 CG C:MET708 4.4 55.0 1.0 CB C:GLU402 4.4 60.9 1.0 SD C:MET708 4.5 55.0 1.0 CE2 C:TYR405 4.6 48.1 1.0 CAV C:ZK11101 4.6 36.9 1.0 OE2 C:GLU402 4.7 60.9 1.0 CAK C:ZK11101 4.8 36.9 1.0 CD2 C:TYR405 4.9 48.1 1.0 CZ C:TYR450 5.0 58.7 1.0 CAW C:ZK11101 5.0 36.9 1.0

Fluorine binding site 10 out of 12 in the Structure of the Complex of Lbd-Tmd Part of Ampa Receptor GLUA2 with Auxiliary Subunit Tarp Gamma-5 Bound to Competitive Antagonist Zk 200775


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 10 of Structure of the Complex of Lbd-Tmd Part of Ampa Receptor GLUA2 with Auxiliary Subunit Tarp Gamma-5 Bound to Competitive Antagonist Zk 200775 within 5.0Å range: probe atom residue distance (Å) B Occ D:F1102 b:28.5 occ:1.00 FAF D:ZK11102 0.0 28.5 1.0 CAZ D:ZK11102 1.4 28.5 1.0 FAG D:ZK11102 2.2 28.5 1.0 FAH D:ZK11102 2.2 28.5 1.0 CAS D:ZK11102 2.4 28.5 1.0 OE1 D:GLU705 2.7 57.9 1.0 CAR D:ZK11102 3.1 28.5 1.0 CAM D:ZK11102 3.2 28.5 1.0 NAX D:ZK11102 3.3 28.5 1.0 CAJ D:ZK11102 3.3 28.5 1.0 OH D:TYR732 3.5 43.4 1.0 CD D:GLU705 3.7 57.9 1.0 CG D:MET708 3.8 58.1 1.0 OG1 D:THR707 4.1 51.8 1.0 CAN D:ZK11102 4.3 28.5 1.0 CAK D:ZK11102 4.3 28.5 1.0 CAI D:ZK11102 4.3 28.5 1.0 OE2 D:GLU705 4.4 57.9 1.0 CE D:MET708 4.5 58.1 1.0 CAV D:ZK11102 4.5 28.5 1.0 CB D:GLU705 4.6 57.9 1.0 CG D:GLU705 4.7 57.9 1.0 CZ D:TYR732 4.7 43.4 1.0 SD D:MET708 4.7 58.1 1.0 CB D:MET708 4.9 58.1 1.0 CAW D:ZK11102 4.9 28.5 1.0

S.P.Gangwar, O.V.Klykov, M.V.Yelshanskaya, A.I.Sobolevsky. Structure of the Complex of Lbd-Tmd Part of Ampa Receptor GLUA2 with Auxiliary Subunit Tarp Gamma-5 Bound to Competitive Antagonist Zk 200775 To Be Published.