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Fluorine in PDB 7s1n: N-Aromatic-Substituted Indazole Derivatives As Brain Penetrant and Orally Bioavailable JNK3 InhibitorsEnzymatic activity of N-Aromatic-Substituted Indazole Derivatives As Brain Penetrant and Orally Bioavailable JNK3 Inhibitors
All present enzymatic activity of N-Aromatic-Substituted Indazole Derivatives As Brain Penetrant and Orally Bioavailable JNK3 Inhibitors:
2.7.11.24; Protein crystallography data
The structure of N-Aromatic-Substituted Indazole Derivatives As Brain Penetrant and Orally Bioavailable JNK3 Inhibitors, PDB code: 7s1n
was solved by
H.Park,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7s1n:
The structure of N-Aromatic-Substituted Indazole Derivatives As Brain Penetrant and Orally Bioavailable JNK3 Inhibitors also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the N-Aromatic-Substituted Indazole Derivatives As Brain Penetrant and Orally Bioavailable JNK3 Inhibitors
(pdb code 7s1n). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the N-Aromatic-Substituted Indazole Derivatives As Brain Penetrant and Orally Bioavailable JNK3 Inhibitors, PDB code: 7s1n: Fluorine binding site 1 out of 1 in 7s1nGo back to![]() ![]()
Fluorine binding site 1 out
of 1 in the N-Aromatic-Substituted Indazole Derivatives As Brain Penetrant and Orally Bioavailable JNK3 Inhibitors
![]() Mono view ![]() Stereo pair view
Reference:
Y.Feng,
H.Park,
J.C.Ryu,
S.O.Yoon.
N -Aromatic-Substituted Indazole Derivatives As Brain-Penetrant and Orally Bioavailable JNK3 Inhibitors. Acs Med.Chem.Lett. V. 12 1546 2021.
Page generated: Fri Nov 5 13:19:20 2021
ISSN: ISSN 1948-5875 PubMed: 34676036 DOI: 10.1021/ACSMEDCHEMLETT.1C00334 |
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