Fluorine in PDB 7sp3: E. Coli Rpph Bound to AP4A

The structure of E. Coli Rpph Bound to AP4A, PDB code: 7sp3 was solved by A.A.Serganov, N.Vasilyev, A.Nuthanakanti, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	18.84 / 1.60
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	79.39, 36.384, 57.801, 90, 102.1, 90
R / Rfree (%)	18.3 / 22

The structure of E. Coli Rpph Bound to AP4A also contains other interesting chemical elements:

Magnesium	(Mg)	3 atoms
Chlorine	(Cl)	1 atom

The binding sites of Fluorine atom in the E. Coli Rpph Bound to AP4A (pdb code 7sp3). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the E. Coli Rpph Bound to AP4A, PDB code: 7sp3:

Fluorine binding site 1 out of 1 in the E. Coli Rpph Bound to AP4A


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of E. Coli Rpph Bound to AP4A within 5.0Å range: probe atom residue distance (Å) B Occ A:F205 b:19.9 occ:1.00 MG A:MG203 1.9 15.3 1.0 MG A:MG204 1.9 17.6 1.0 O A:HOH393 2.5 24.5 0.6 O2A A:B4P201 2.6 18.0 0.7 O1A A:B4P201 2.6 11.3 0.7 PA A:B4P201 2.7 20.3 0.7 O A:HOH318 2.8 18.2 1.0 O5E A:B4P201 2.8 22.1 0.7 OE2 A:GLU120 2.9 17.6 1.0 O A:HOH321 2.9 15.8 1.0 O A:HOH384 3.0 20.4 1.0 OE2 A:GLU53 3.0 16.1 1.0 OE1 A:GLU53 3.1 16.9 1.0 CD A:GLU53 3.5 18.4 1.0 C5E A:B4P201 3.6 26.8 0.7 O A:HOH322 3.6 25.9 1.0 OE1 A:GLU56 3.8 19.8 1.0 C5E A:B4P201 3.9 19.4 0.3 O A:HOH393 3.9 25.0 0.4 CD A:GLU120 3.9 20.4 1.0 OE2 A:GLU57 4.0 15.7 1.0 O A:HOH343 4.1 20.9 1.0 O3A A:B4P201 4.3 20.7 0.7 OE1 A:GLU120 4.4 18.9 1.0 MG A:MG202 4.4 17.4 1.0 CA A:GLY38 4.9 15.9 1.0 O A:HOH399 5.0 32.3 1.0 CG A:GLU53 5.0 16.9 1.0 CD A:GLU56 5.0 14.5 1.0

R.Levenson-Palmer, D.J.Luciano, N.Vasilyev, A.Nuthanakanti, A.Serganov, J.G.Belasco. A Distinct Rna Recognition Mechanism Governs Np 4 Decapping By Rpph. Proc.Natl.Acad.Sci.Usa V. 119 2022.
ISSN: ESSN 1091-6490
PubMed: 35131855
DOI: 10.1073/PNAS.2117318119