Fluorine in PDB 7t0y: The Ribosomal Rna Processing 1B Protein Phosphatase-1 Holoenzyme

All present enzymatic activity of The Ribosomal Rna Processing 1B Protein Phosphatase-1 Holoenzyme:
3.1.3.16;

The structure of The Ribosomal Rna Processing 1B Protein Phosphatase-1 Holoenzyme, PDB code: 7t0y was solved by G.Srivastava, R.Page, W.Peti, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.27 / 1.80
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	83.528, 160.387, 50.615, 90, 90, 90
R / Rfree (%)	20.8 / 24.6

The structure of The Ribosomal Rna Processing 1B Protein Phosphatase-1 Holoenzyme also contains other interesting chemical elements:

Manganese	(Mn)	4 atoms
Bromine	(Br)	3 atoms

The binding sites of Fluorine atom in the The Ribosomal Rna Processing 1B Protein Phosphatase-1 Holoenzyme (pdb code 7t0y). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the The Ribosomal Rna Processing 1B Protein Phosphatase-1 Holoenzyme, PDB code: 7t0y:

Fluorine binding site 1 out of 1 in the The Ribosomal Rna Processing 1B Protein Phosphatase-1 Holoenzyme


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of The Ribosomal Rna Processing 1B Protein Phosphatase-1 Holoenzyme within 5.0Å range: probe atom residue distance (Å) B Occ A:F408 b:27.3 occ:1.00 N A:ASN86 3.1 16.0 1.0 O A:HOH612 3.5 36.6 1.0 CA A:SER85 3.6 21.3 1.0 C A:PRO58 3.7 32.2 1.0 N A:LEU59 3.7 28.7 1.0 O A:PRO58 3.7 26.5 1.0 CB A:SER85 3.8 23.1 1.0 C A:SER85 3.8 21.1 1.0 CB A:PRO58 3.9 30.4 1.0 O A:ASN86 4.0 21.6 1.0 CB A:ASN86 4.0 20.8 1.0 CA A:ASN86 4.0 20.1 1.0 ND2 A:ASN86 4.0 22.1 1.0 CA A:LEU59 4.0 23.6 1.0 O A:HOH634 4.0 40.1 1.0 CG A:PRO58 4.0 30.0 1.0 CG A:ASN86 4.2 27.5 1.0 CG A:LYS60 4.4 29.1 1.0 C A:LEU59 4.4 28.0 1.0 OG A:SER85 4.4 25.6 1.0 CA A:PRO58 4.5 25.3 1.0 C A:ASN86 4.5 22.6 1.0 N A:LYS60 4.5 21.3 1.0 CE A:LYS60 4.7 28.5 1.0 O A:GLU84 4.9 25.2 1.0 OD1 A:ASN86 4.9 25.5 1.0 N A:SER85 5.0 20.9 1.0

G.Srivastava, R.Bajaj, G.S.Kumar, A.Gaudreau-Lapierre, H.Nicolas, D.Chamousset, D.Kreitler, W.Peti, L.Trinkle-Mulcahy, R.Page. The Ribosomal Rna Processing 1B:Protein Phosphatase 1 Holoenzyme Reveals Non-Canonical PP1 Interaction Motifs. Cell Rep V. 41 11726 2022.
ISSN: ESSN 2211-1247
PubMed: 36450254
DOI: 10.1016/J.CELREP.2022.111726