Fluorine in PDB 7t3b: GATOR1-Rag-Ragulator - Gap Complex
Other elements in 7t3b:
The structure of GATOR1-Rag-Ragulator - Gap Complex also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the GATOR1-Rag-Ragulator - Gap Complex
(pdb code 7t3b). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 6 binding sites of Fluorine where determined in the
GATOR1-Rag-Ragulator - Gap Complex, PDB code: 7t3b:
Jump to Fluorine binding site number:
1;
2;
3;
4;
5;
6;
Fluorine binding site 1 out
of 6 in 7t3b
Go back to
Fluorine Binding Sites List in 7t3b
Fluorine binding site 1 out
of 6 in the GATOR1-Rag-Ragulator - Gap Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 1 of GATOR1-Rag-Ragulator - Gap Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:F502
b:303.3
occ:1.00
|
F1
|
E:AF3502
|
0.0
|
303.3
|
1.0
|
|
AL
|
E:AF3502
|
1.7
|
303.3
|
1.0
|
|
NZ
|
E:LYS74
|
2.6
|
282.3
|
1.0
|
|
O2B
|
E:GDP501
|
2.6
|
268.1
|
1.0
|
|
O
|
E:THR96
|
2.7
|
303.9
|
1.0
|
|
F3
|
E:AF3502
|
2.9
|
303.3
|
1.0
|
|
F2
|
E:AF3502
|
3.0
|
303.3
|
1.0
|
|
N
|
E:THR96
|
3.1
|
303.9
|
1.0
|
|
O1B
|
E:GDP501
|
3.2
|
268.1
|
1.0
|
|
PB
|
E:GDP501
|
3.2
|
268.1
|
1.0
|
|
CE
|
E:LYS74
|
3.3
|
282.3
|
1.0
|
|
C
|
E:THR96
|
3.3
|
303.9
|
1.0
|
|
CB
|
E:THR96
|
3.3
|
303.9
|
1.0
|
|
CA
|
E:THR96
|
3.4
|
303.9
|
1.0
|
|
O3B
|
E:GDP501
|
3.5
|
268.1
|
1.0
|
|
O
|
E:PHE117
|
3.7
|
305.2
|
1.0
|
|
N
|
E:GLY119
|
3.7
|
301.4
|
1.0
|
|
OG1
|
E:THR96
|
3.9
|
303.9
|
1.0
|
|
C
|
E:SER95
|
4.1
|
298.7
|
1.0
|
|
CA
|
E:GLY119
|
4.1
|
301.4
|
1.0
|
|
OG
|
E:SER75
|
4.4
|
276.1
|
1.0
|
|
N
|
E:ASN97
|
4.4
|
306.9
|
1.0
|
|
C
|
E:PRO118
|
4.5
|
308.8
|
1.0
|
|
CA
|
E:SER95
|
4.6
|
298.7
|
1.0
|
|
CG2
|
E:THR96
|
4.6
|
303.9
|
1.0
|
|
CD
|
E:LYS74
|
4.6
|
282.3
|
1.0
|
|
OD1
|
E:ASP116
|
4.7
|
294.4
|
1.0
|
|
CA
|
E:PRO118
|
4.7
|
308.8
|
1.0
|
|
O3A
|
E:GDP501
|
4.8
|
268.1
|
1.0
|
|
CE
|
E:MET67
|
4.8
|
278.2
|
1.0
|
|
C
|
E:PHE117
|
4.8
|
305.2
|
1.0
|
|
O
|
E:SER95
|
4.9
|
298.7
|
1.0
|
|
Fluorine binding site 2 out
of 6 in 7t3b
Go back to
Fluorine Binding Sites List in 7t3b
Fluorine binding site 2 out
of 6 in the GATOR1-Rag-Ragulator - Gap Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 2 of GATOR1-Rag-Ragulator - Gap Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:F502
b:303.3
occ:1.00
|
F2
|
E:AF3502
|
0.0
|
303.3
|
1.0
|
|
AL
|
E:AF3502
|
1.7
|
303.3
|
1.0
|
|
O1B
|
E:GDP501
|
2.3
|
268.1
|
1.0
|
|
F1
|
E:AF3502
|
3.0
|
303.3
|
1.0
|
|
F3
|
E:AF3502
|
3.0
|
303.3
|
1.0
|
|
N
|
E:ARG71
|
3.0
|
256.7
|
1.0
|
|
CD
|
E:ARG70
|
3.3
|
263.6
|
1.0
|
|
CA
|
E:GLY119
|
3.3
|
301.4
|
1.0
|
|
NE
|
E:ARG70
|
3.5
|
263.6
|
1.0
|
|
CA
|
E:ARG70
|
3.5
|
263.6
|
1.0
|
|
PB
|
E:GDP501
|
3.6
|
268.1
|
1.0
|
|
C
|
E:ARG70
|
3.7
|
263.6
|
1.0
|
|
O2B
|
E:GDP501
|
3.9
|
268.1
|
1.0
|
|
CA
|
E:ARG71
|
4.0
|
256.7
|
1.0
|
|
N
|
E:GLY119
|
4.0
|
301.4
|
1.0
|
|
CB
|
E:ARG70
|
4.0
|
263.6
|
1.0
|
|
CG
|
E:ARG70
|
4.2
|
263.6
|
1.0
|
|
O3B
|
E:GDP501
|
4.2
|
268.1
|
1.0
|
|
O
|
E:LEU69
|
4.3
|
265.7
|
1.0
|
|
C
|
E:GLY119
|
4.3
|
301.4
|
1.0
|
|
N
|
E:ARG70
|
4.6
|
263.6
|
1.0
|
|
CE
|
E:LYS74
|
4.7
|
282.3
|
1.0
|
|
CZ
|
E:ARG70
|
4.7
|
263.6
|
1.0
|
|
O1A
|
E:GDP501
|
4.8
|
268.1
|
1.0
|
|
O
|
E:GLY119
|
4.8
|
301.4
|
1.0
|
|
O3A
|
E:GDP501
|
4.8
|
268.1
|
1.0
|
|
NZ
|
E:LYS74
|
4.8
|
282.3
|
1.0
|
|
CG
|
E:ARG71
|
4.9
|
256.7
|
1.0
|
|
C
|
E:LEU69
|
4.9
|
265.7
|
1.0
|
|
CB
|
E:ARG71
|
4.9
|
256.7
|
1.0
|
|
N
|
E:SER72
|
4.9
|
271.1
|
1.0
|
|
CD
|
E:ARG71
|
4.9
|
256.7
|
1.0
|
|
O
|
E:ARG70
|
5.0
|
263.6
|
1.0
|
|
N
|
E:THR96
|
5.0
|
303.9
|
1.0
|
|
Fluorine binding site 3 out
of 6 in 7t3b
Go back to
Fluorine Binding Sites List in 7t3b
Fluorine binding site 3 out
of 6 in the GATOR1-Rag-Ragulator - Gap Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 3 of GATOR1-Rag-Ragulator - Gap Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:F502
b:303.3
occ:1.00
|
F3
|
E:AF3502
|
0.0
|
303.3
|
1.0
|
|
AL
|
E:AF3502
|
1.7
|
303.3
|
1.0
|
|
NE
|
E:ARG70
|
2.8
|
263.6
|
1.0
|
|
F1
|
E:AF3502
|
2.9
|
303.3
|
1.0
|
|
F2
|
E:AF3502
|
3.0
|
303.3
|
1.0
|
|
C
|
E:SER95
|
3.2
|
298.7
|
1.0
|
|
CD
|
E:ARG70
|
3.3
|
263.6
|
1.0
|
|
CB
|
E:SER95
|
3.3
|
298.7
|
1.0
|
|
N
|
E:THR96
|
3.3
|
303.9
|
1.0
|
|
CZ
|
E:ARG70
|
3.4
|
263.6
|
1.0
|
|
CA
|
E:SER95
|
3.5
|
298.7
|
1.0
|
|
N
|
E:GLY119
|
3.5
|
301.4
|
1.0
|
|
C
|
E:THR96
|
3.6
|
303.9
|
1.0
|
|
O
|
E:THR96
|
3.6
|
303.9
|
1.0
|
|
O
|
E:SER95
|
3.7
|
298.7
|
1.0
|
|
NH2
|
E:ARG70
|
3.7
|
263.6
|
1.0
|
|
CA
|
E:GLY119
|
3.8
|
301.4
|
1.0
|
|
N
|
E:ASN97
|
3.9
|
306.9
|
1.0
|
|
O1B
|
E:GDP501
|
4.0
|
268.1
|
1.0
|
|
O2B
|
E:GDP501
|
4.0
|
268.1
|
1.0
|
|
CA
|
E:THR96
|
4.1
|
303.9
|
1.0
|
|
CA
|
E:ASN97
|
4.3
|
306.9
|
1.0
|
|
NH1
|
E:ARG70
|
4.3
|
263.6
|
1.0
|
|
OG
|
E:SER95
|
4.4
|
298.7
|
1.0
|
|
CB
|
E:ASN97
|
4.5
|
306.9
|
1.0
|
|
O
|
E:GLY119
|
4.5
|
301.4
|
1.0
|
|
PB
|
E:GDP501
|
4.7
|
268.1
|
1.0
|
|
C
|
E:GLY119
|
4.7
|
301.4
|
1.0
|
|
C
|
E:PRO118
|
4.7
|
308.8
|
1.0
|
|
CG
|
E:ARG70
|
4.8
|
263.6
|
1.0
|
|
N
|
E:SER95
|
5.0
|
298.7
|
1.0
|
|
CA
|
E:PRO118
|
5.0
|
308.8
|
1.0
|
|
Fluorine binding site 4 out
of 6 in 7t3b
Go back to
Fluorine Binding Sites List in 7t3b
Fluorine binding site 4 out
of 6 in the GATOR1-Rag-Ragulator - Gap Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 4 of GATOR1-Rag-Ragulator - Gap Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:F601
b:131.5
occ:1.00
|
F1
|
D:AF3601
|
0.0
|
131.5
|
1.0
|
|
AL
|
D:AF3601
|
1.7
|
131.5
|
1.0
|
|
OG1
|
D:THR42
|
2.3
|
122.1
|
1.0
|
|
O2B
|
B:GDP501
|
2.6
|
142.5
|
1.0
|
|
O
|
D:THR42
|
2.7
|
122.1
|
1.0
|
|
O1B
|
B:GDP501
|
2.8
|
142.5
|
1.0
|
|
F3
|
D:AF3601
|
2.9
|
131.5
|
1.0
|
|
F2
|
D:AF3601
|
2.9
|
131.5
|
1.0
|
|
PB
|
B:GDP501
|
3.3
|
142.5
|
1.0
|
|
CE
|
D:LYS20
|
3.3
|
124.5
|
1.0
|
|
NZ
|
D:LYS20
|
3.5
|
124.5
|
1.0
|
|
CB
|
D:THR42
|
3.6
|
122.1
|
1.0
|
|
C
|
D:THR42
|
3.6
|
122.1
|
1.0
|
|
N
|
D:THR42
|
3.8
|
122.1
|
1.0
|
|
CA
|
D:THR42
|
3.9
|
122.1
|
1.0
|
|
O
|
D:CYS63
|
3.9
|
161.1
|
1.0
|
|
CA
|
D:GLY64
|
4.0
|
135.4
|
1.0
|
|
OG1
|
D:THR21
|
4.1
|
119.6
|
1.0
|
|
N
|
D:GLY65
|
4.2
|
142.7
|
1.0
|
|
O3B
|
B:GDP501
|
4.4
|
142.5
|
1.0
|
|
O3A
|
B:GDP501
|
4.4
|
142.5
|
1.0
|
|
CD
|
D:LYS20
|
4.5
|
124.5
|
1.0
|
|
CG2
|
D:THR42
|
4.6
|
122.1
|
1.0
|
|
C
|
D:GLY64
|
4.6
|
135.4
|
1.0
|
|
CG
|
D:LYS20
|
4.7
|
124.5
|
1.0
|
|
C
|
D:CYS63
|
4.7
|
161.1
|
1.0
|
|
NH2
|
B:ARG78
|
4.8
|
126.1
|
1.0
|
|
N
|
D:GLY64
|
4.8
|
135.4
|
1.0
|
|
OE1
|
D:GLN66
|
4.8
|
131.6
|
1.0
|
|
C
|
D:ALA41
|
4.8
|
118.0
|
1.0
|
|
N
|
D:ILE43
|
4.9
|
131.2
|
1.0
|
|
OD1
|
D:ASP62
|
5.0
|
146.8
|
1.0
|
|
Fluorine binding site 5 out
of 6 in 7t3b
Go back to
Fluorine Binding Sites List in 7t3b
Fluorine binding site 5 out
of 6 in the GATOR1-Rag-Ragulator - Gap Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 5 of GATOR1-Rag-Ragulator - Gap Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:F601
b:131.5
occ:1.00
|
F2
|
D:AF3601
|
0.0
|
131.5
|
1.0
|
|
AL
|
D:AF3601
|
1.7
|
131.5
|
1.0
|
|
OE1
|
D:GLN66
|
2.6
|
131.6
|
1.0
|
|
NE2
|
D:GLN66
|
2.9
|
131.6
|
1.0
|
|
F3
|
D:AF3601
|
2.9
|
131.5
|
1.0
|
|
F1
|
D:AF3601
|
2.9
|
131.5
|
1.0
|
|
O
|
D:THR42
|
3.0
|
122.1
|
1.0
|
|
CD
|
D:GLN66
|
3.1
|
131.6
|
1.0
|
|
NH2
|
B:ARG78
|
3.2
|
126.1
|
1.0
|
|
O1B
|
B:GDP501
|
3.7
|
142.5
|
1.0
|
|
O2B
|
B:GDP501
|
3.9
|
142.5
|
1.0
|
|
C
|
D:THR42
|
3.9
|
122.1
|
1.0
|
|
N
|
D:GLY65
|
4.1
|
142.7
|
1.0
|
|
N
|
D:THR42
|
4.1
|
122.1
|
1.0
|
|
PB
|
B:GDP501
|
4.2
|
142.5
|
1.0
|
|
O3B
|
B:GDP501
|
4.3
|
142.5
|
1.0
|
|
CZ
|
B:ARG78
|
4.3
|
126.1
|
1.0
|
|
C
|
D:ALA41
|
4.4
|
118.0
|
1.0
|
|
CG2
|
D:ILE43
|
4.4
|
131.2
|
1.0
|
|
CA
|
D:ALA41
|
4.4
|
118.0
|
1.0
|
|
CB
|
D:ALA41
|
4.5
|
118.0
|
1.0
|
|
OG1
|
D:THR42
|
4.5
|
122.1
|
1.0
|
|
CA
|
D:GLY64
|
4.6
|
135.4
|
1.0
|
|
CG
|
D:GLN66
|
4.6
|
131.6
|
1.0
|
|
CA
|
D:THR42
|
4.6
|
122.1
|
1.0
|
|
OG
|
D:SER16
|
4.7
|
131.4
|
1.0
|
|
N
|
D:ILE43
|
4.8
|
131.2
|
1.0
|
|
CZ
|
B:PHE15
|
4.8
|
119.8
|
1.0
|
|
CA
|
D:ILE43
|
4.8
|
131.2
|
1.0
|
|
C
|
D:GLY64
|
4.9
|
135.4
|
1.0
|
|
N
|
D:GLN66
|
4.9
|
131.6
|
1.0
|
|
NE
|
B:ARG78
|
5.0
|
126.1
|
1.0
|
|
Fluorine binding site 6 out
of 6 in 7t3b
Go back to
Fluorine Binding Sites List in 7t3b
Fluorine binding site 6 out
of 6 in the GATOR1-Rag-Ragulator - Gap Complex
 Mono view
 Stereo pair view
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A full contact list of Fluorine with other atoms in the F binding
site number 6 of GATOR1-Rag-Ragulator - Gap Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:F601
b:131.5
occ:1.00
|
F3
|
D:AF3601
|
0.0
|
131.5
|
1.0
|
|
AL
|
D:AF3601
|
1.7
|
131.5
|
1.0
|
|
O2B
|
B:GDP501
|
2.3
|
142.5
|
1.0
|
|
NZ
|
D:LYS20
|
2.4
|
124.5
|
1.0
|
|
F1
|
D:AF3601
|
2.9
|
131.5
|
1.0
|
|
F2
|
D:AF3601
|
2.9
|
131.5
|
1.0
|
|
CA
|
D:SER16
|
3.3
|
131.4
|
1.0
|
|
CE
|
D:LYS20
|
3.3
|
124.5
|
1.0
|
|
PB
|
B:GDP501
|
3.4
|
142.5
|
1.0
|
|
O3B
|
B:GDP501
|
3.7
|
142.5
|
1.0
|
|
O
|
D:LYS15
|
3.7
|
134.4
|
1.0
|
|
N
|
D:GLY65
|
3.7
|
142.7
|
1.0
|
|
OE1
|
D:GLN66
|
3.9
|
131.6
|
1.0
|
|
N
|
D:SER16
|
3.9
|
131.4
|
1.0
|
|
N
|
D:GLY17
|
3.9
|
129.3
|
1.0
|
|
OG
|
D:SER16
|
3.9
|
131.4
|
1.0
|
|
NH2
|
B:ARG78
|
3.9
|
126.1
|
1.0
|
|
CA
|
D:GLY65
|
4.0
|
142.7
|
1.0
|
|
O1B
|
B:GDP501
|
4.0
|
142.5
|
1.0
|
|
CB
|
D:SER16
|
4.0
|
131.4
|
1.0
|
|
C
|
D:LYS15
|
4.1
|
134.4
|
1.0
|
|
C
|
D:SER16
|
4.1
|
131.4
|
1.0
|
|
CZ
|
B:ARG78
|
4.3
|
126.1
|
1.0
|
|
O1A
|
B:GDP501
|
4.3
|
142.5
|
1.0
|
|
CD
|
D:GLN66
|
4.6
|
131.6
|
1.0
|
|
NE
|
B:ARG78
|
4.7
|
126.1
|
1.0
|
|
NE2
|
D:GLN66
|
4.7
|
131.6
|
1.0
|
|
CD
|
D:LYS20
|
4.7
|
124.5
|
1.0
|
|
O3A
|
B:GDP501
|
4.7
|
142.5
|
1.0
|
|
NH1
|
B:ARG78
|
4.7
|
126.1
|
1.0
|
|
C
|
D:GLY65
|
4.7
|
142.7
|
1.0
|
|
C
|
D:GLY64
|
4.8
|
135.4
|
1.0
|
|
O
|
D:THR42
|
4.9
|
122.1
|
1.0
|
|
Reference:
S.B.Egri,
C.Ouch,
H.T.Chou,
Z.Yu,
K.Song,
C.Xu,
K.Shen.
Cryo-Em Structures of the Human GATOR1-Rag-Ragulator Complex Reveal A Spatial-Constraint Regulated Gap Mechanism. Mol.Cell V. 82 1836 2022.
ISSN: ISSN 1097-2765
PubMed: 35338845
DOI: 10.1016/J.MOLCEL.2022.03.002
Page generated: Fri Aug 2 13:15:42 2024
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