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Fluorine in PDB 7tel: Sars-Cov-2 3CLPRO in Complex with N-(4-(1H-Imidazol-4-Yl)Phenyl)-N-(3- Chloro-5-Fluorobenzyl)-2-(Isoquinolin-4-Yl)AcetamideEnzymatic activity of Sars-Cov-2 3CLPRO in Complex with N-(4-(1H-Imidazol-4-Yl)Phenyl)-N-(3- Chloro-5-Fluorobenzyl)-2-(Isoquinolin-4-Yl)Acetamide
All present enzymatic activity of Sars-Cov-2 3CLPRO in Complex with N-(4-(1H-Imidazol-4-Yl)Phenyl)-N-(3- Chloro-5-Fluorobenzyl)-2-(Isoquinolin-4-Yl)Acetamide:
3.4.22.69; Protein crystallography data
The structure of Sars-Cov-2 3CLPRO in Complex with N-(4-(1H-Imidazol-4-Yl)Phenyl)-N-(3- Chloro-5-Fluorobenzyl)-2-(Isoquinolin-4-Yl)Acetamide, PDB code: 7tel
was solved by
C.M.Goins,
S.R.Stauffer,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7tel:
The structure of Sars-Cov-2 3CLPRO in Complex with N-(4-(1H-Imidazol-4-Yl)Phenyl)-N-(3- Chloro-5-Fluorobenzyl)-2-(Isoquinolin-4-Yl)Acetamide also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Sars-Cov-2 3CLPRO in Complex with N-(4-(1H-Imidazol-4-Yl)Phenyl)-N-(3- Chloro-5-Fluorobenzyl)-2-(Isoquinolin-4-Yl)Acetamide
(pdb code 7tel). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Sars-Cov-2 3CLPRO in Complex with N-(4-(1H-Imidazol-4-Yl)Phenyl)-N-(3- Chloro-5-Fluorobenzyl)-2-(Isoquinolin-4-Yl)Acetamide, PDB code: 7tel: Fluorine binding site 1 out of 1 in 7telGo back to Fluorine Binding Sites List in 7tel
Fluorine binding site 1 out
of 1 in the Sars-Cov-2 3CLPRO in Complex with N-(4-(1H-Imidazol-4-Yl)Phenyl)-N-(3- Chloro-5-Fluorobenzyl)-2-(Isoquinolin-4-Yl)Acetamide
Mono view Stereo pair view
Reference:
A.Hooper,
C.M.Goins,
T.Romigh,
E.Rico,
A.A.Lindsey,
N.Wang,
J.Macondal,
S.R.Stauffer.
P1 Subpocket Optimization of A Non-Covalent Non-Canonical Sars-COV2 Inhibitor Based Upon ML300 To Be Published.
Page generated: Fri Aug 2 13:26:40 2024
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