Fluorine in PDB 7tqy: CAKIP3[2-482] - Adp-Alfx in Complex with A Microtubule

The structure of CAKIP3[2-482] - Adp-Alfx in Complex with A Microtubule also contains other interesting chemical elements:

Magnesium	(Mg)	2 atoms
Aluminium	(Al)	1 atom

The binding sites of Fluorine atom in the CAKIP3[2-482] - Adp-Alfx in Complex with A Microtubule (pdb code 7tqy). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the CAKIP3[2-482] - Adp-Alfx in Complex with A Microtubule, PDB code: 7tqy:
Jump to Fluorine binding site number: 1; 2; 3;

Fluorine binding site 1 out of 3 in the CAKIP3[2-482] - Adp-Alfx in Complex with A Microtubule


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of CAKIP3[2-482] - Adp-Alfx in Complex with A Microtubule within 5.0Å range: probe atom residue distance (Å) B Occ K:F800 b:71.7 occ:1.00 F1 K:AF3800 0.0 71.7 1.0 AL K:AF3800 1.6 66.9 1.0 O1B K:ADP801 2.2 68.2 1.0 OG1 K:THR187 2.7 75.6 1.0 F3 K:AF3800 2.8 73.0 1.0 F2 K:AF3800 2.8 70.9 1.0 ND2 K:ASN297 3.1 79.5 1.0 N K:GLY188 3.1 74.6 1.0 OG K:SER300 3.3 75.9 1.0 PB K:ADP801 3.5 72.2 1.0 CB K:THR187 3.5 72.8 1.0 CA K:THR187 3.5 71.7 1.0 C K:THR187 3.8 72.7 1.0 CG K:ASN297 4.0 78.9 1.0 O3A K:ADP801 4.0 70.8 1.0 OD1 K:ASN297 4.0 80.6 1.0 O2B K:ADP801 4.0 75.5 1.0 CA K:GLY188 4.0 71.7 1.0 CB K:SER300 4.2 73.3 1.0 CA K:SER300 4.4 69.0 1.0 N K:SER301 4.7 62.3 1.0 MG K:MG802 4.7 60.3 1.0 O3B K:ADP801 4.7 73.1 1.0 N K:THR187 4.9 67.3 1.0 CG2 K:THR187 4.9 72.6 1.0 O K:THR187 4.9 72.8 1.0

Fluorine binding site 2 out of 3 in the CAKIP3[2-482] - Adp-Alfx in Complex with A Microtubule


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of CAKIP3[2-482] - Adp-Alfx in Complex with A Microtubule within 5.0Å range: probe atom residue distance (Å) B Occ K:F800 b:70.9 occ:1.00 F2 K:AF3800 0.0 70.9 1.0 AL K:AF3800 1.6 66.9 1.0 N K:GLY336 2.8 67.8 1.0 F3 K:AF3800 2.8 73.0 1.0 F1 K:AF3800 2.8 71.7 1.0 O K:SER301 3.2 66.1 1.0 CA K:GLY336 3.5 66.1 1.0 OG K:SER300 3.7 75.9 1.0 C K:ALA335 3.8 64.1 1.0 CA K:ALA335 3.8 60.4 1.0 O1B K:ADP801 3.9 68.2 1.0 CB K:ALA335 4.0 63.1 1.0 O K:GLY336 4.1 65.9 1.0 OG1 K:THR187 4.1 75.6 1.0 C K:GLY336 4.3 67.2 1.0 C K:SER301 4.3 61.9 1.0 CB K:THR187 4.3 72.8 1.0 N K:SER301 4.4 62.3 1.0 CA K:THR187 4.5 71.7 1.0 NH1 K:ARG302 4.6 67.1 1.0 MG K:MG802 4.7 60.3 1.0 CA K:SER301 4.8 57.4 1.0 NZ K:LYS191 4.8 72.6 1.0 CB K:SER301 4.8 61.2 1.0 O K:ALA335 4.9 63.7 1.0 CB K:SER300 5.0 73.3 1.0

Fluorine binding site 3 out of 3 in the CAKIP3[2-482] - Adp-Alfx in Complex with A Microtubule


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of CAKIP3[2-482] - Adp-Alfx in Complex with A Microtubule within 5.0Å range: probe atom residue distance (Å) B Occ K:F800 b:73.0 occ:1.00 F3 K:AF3800 0.0 73.0 1.0 AL K:AF3800 1.6 66.9 1.0 MG K:MG802 2.1 60.3 1.0 O2B K:ADP801 2.5 75.5 1.0 O1B K:ADP801 2.8 68.2 1.0 F2 K:AF3800 2.8 70.9 1.0 F1 K:AF3800 2.8 71.7 1.0 N K:SER301 3.0 62.3 1.0 PB K:ADP801 3.1 72.2 1.0 CB K:SER301 3.3 61.2 1.0 OG K:SER301 3.4 63.5 1.0 CA K:SER301 3.6 57.4 1.0 O K:SER301 3.7 66.1 1.0 C K:SER300 4.0 70.1 1.0 OG K:SER300 4.1 75.9 1.0 C K:SER301 4.1 61.9 1.0 CA K:SER300 4.2 69.0 1.0 O3A K:ADP801 4.2 70.8 1.0 OG1 K:THR192 4.3 66.0 1.0 O3B K:ADP801 4.3 73.1 1.0 N K:GLY336 4.8 67.8 1.0 CB K:SER300 4.8 73.3 1.0 O2A K:ADP801 4.8 73.6 1.0 CA K:ALA335 4.9 60.4 1.0

B.Hunter, M.P.M.H.Benoit, A.B.Asenjo, C.Doubleday, D.Trofimova, C.Frazer, I.Shoukat, H.Sosa, J.S.Allingham. Kinesin-8-Specific Loop-2 Controls the Dual Activities of the Motor Domain According to Tubulin Protofilament Shape. Nat Commun V. 13 4198 2022.
ISSN: ESSN 2041-1723
PubMed: 35859148
DOI: 10.1038/S41467-022-31794-3