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Fluorine in PDB 7tvb: STAT5A Core in Complex with AK305Protein crystallography data
The structure of STAT5A Core in Complex with AK305, PDB code: 7tvb
was solved by
J.L.Meagher,
J.A.Stuckey,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the STAT5A Core in Complex with AK305
(pdb code 7tvb). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the STAT5A Core in Complex with AK305, PDB code: 7tvb: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 7tvbGo back to Fluorine Binding Sites List in 7tvb
Fluorine binding site 1 out
of 2 in the STAT5A Core in Complex with AK305
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 7tvbGo back to Fluorine Binding Sites List in 7tvb
Fluorine binding site 2 out
of 2 in the STAT5A Core in Complex with AK305
Mono view Stereo pair view
Reference:
A.Kaneshige,
L.Bai,
M.Wang,
D.Mceachern,
J.L.Meagher,
R.Xu,
Y.Wang,
W.Jiang,
H.Metwally,
P.D.Kirchhoff,
L.Zhao,
H.Jiang,
M.Wang,
B.Wen,
D.Sun,
J.A.Stuckey,
S.Wang.
A Selective Small-Molecule STAT5 Protac Degrader Capable of Achieving Tumor Regression in Vivo. Nat.Chem.Biol. 2023.
Page generated: Fri Aug 2 13:44:37 2024
ISSN: ESSN 1552-4469 PubMed: 36732620 DOI: 10.1038/S41589-022-01248-4 |
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