Fluorine in PDB 7vc3: Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with Inhibitor L97 and L-Proline at 1.97 A Resolution

The structure of Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with Inhibitor L97 and L-Proline at 1.97 A Resolution, PDB code: 7vc3 was solved by N.Malhotra, Y.Manickam, A.Sharma, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	52.68 / 1.97
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	114.733, 73.644, 74.906, 90, 111.38, 90
R / Rfree (%)	17.5 / 21.7

The structure of Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with Inhibitor L97 and L-Proline at 1.97 A Resolution also contains other interesting chemical elements:

Chlorine	(Cl)	11 atoms
Sodium	(Na)	1 atom

The binding sites of Fluorine atom in the Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with Inhibitor L97 and L-Proline at 1.97 A Resolution (pdb code 7vc3). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with Inhibitor L97 and L-Proline at 1.97 A Resolution, PDB code: 7vc3:

Fluorine binding site 1 out of 1 in the Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with Inhibitor L97 and L-Proline at 1.97 A Resolution


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with Inhibitor L97 and L-Proline at 1.97 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:F1001 b:45.5 occ:0.94 F A:1XK1001 0.0 45.5 0.9 C10 A:1XK1001 1.3 49.0 0.9 C11 A:1XK1001 2.3 46.5 0.9 C9 A:1XK1001 2.3 43.8 0.9 CB A:PRO476 3.2 52.8 1.0 CA A:PRO476 3.3 51.9 1.0 O A:LYS474 3.3 52.6 1.0 NE A:ARG483 3.4 78.8 1.0 N A:PRO476 3.5 56.2 1.0 C12 A:1XK1001 3.5 43.0 0.9 C8 A:1XK1001 3.6 47.0 0.9 CG A:ARG483 3.7 59.0 1.0 CD A:PRO476 3.9 57.6 1.0 C A:GLN475 3.9 51.1 1.0 CG A:PRO476 4.0 61.8 1.0 O A:ARG481 4.0 40.5 1.0 C13 A:1XK1001 4.0 44.7 0.9 NH2 A:ARG483 4.2 84.4 1.0 CD A:ARG483 4.2 60.4 1.0 O A:GLU472 4.2 66.4 1.0 O A:GLN475 4.2 56.8 1.0 CZ A:ARG483 4.3 84.4 1.0 C A:LYS474 4.3 63.8 1.0 CA A:GLY363 4.3 54.0 1.0 N A:ARG483 4.4 38.4 1.0 CA A:THR482 4.6 44.4 1.0 C A:THR482 4.6 43.8 1.0 C A:ARG481 4.6 49.7 1.0 C A:PRO476 4.7 50.8 1.0 C14 A:1XK1001 4.7 44.8 0.9 CA A:GLN475 4.8 60.9 1.0 CB A:ARG483 4.8 42.1 1.0 C7 A:1XK1001 4.8 44.2 0.9 CB A:GLU472 4.9 61.1 1.0 N A:THR482 4.9 50.1 1.0 N A:GLN475 4.9 64.0 1.0 CA A:ARG483 4.9 41.5 1.0 O A:GLY363 5.0 55.6 1.0

N.Malhotra, Y.Manickam, A.Sharma. Tgprs with Inhibitor L97 To Be Published.