Fluorine in PDB 7wlj: Cryoem Structure of Human Low-Voltage Activated T-Type Calcium Channel CAV3.3 in Complex with Mibefradil (Mib)

The structure of Cryoem Structure of Human Low-Voltage Activated T-Type Calcium Channel CAV3.3 in Complex with Mibefradil (Mib) also contains other interesting chemical elements:

Calcium

(Ca)

1 atom

The binding sites of Fluorine atom in the Cryoem Structure of Human Low-Voltage Activated T-Type Calcium Channel CAV3.3 in Complex with Mibefradil (Mib) (pdb code 7wlj). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Cryoem Structure of Human Low-Voltage Activated T-Type Calcium Channel CAV3.3 in Complex with Mibefradil (Mib), PDB code: 7wlj:

Fluorine binding site 1 out of 1 in the Cryoem Structure of Human Low-Voltage Activated T-Type Calcium Channel CAV3.3 in Complex with Mibefradil (Mib)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Cryoem Structure of Human Low-Voltage Activated T-Type Calcium Channel CAV3.3 in Complex with Mibefradil (Mib) within 5.0Å range: probe atom residue distance (Å) B Occ A:F2301 b:69.8 occ:1.00 F31 A:MWV2301 0.0 69.8 1.0 C30 A:MWV2301 1.4 69.8 1.0 C29 A:MWV2301 2.4 69.8 1.0 C32 A:MWV2301 2.4 69.8 1.0 CB A:LEU1721 3.0 75.5 1.0 C A:LEU1721 3.6 75.5 1.0 C28 A:MWV2301 3.6 69.8 1.0 C26 A:MWV2301 3.7 69.8 1.0 ND2 A:ASN391 3.7 77.2 1.0 CE1 A:PHE387 3.8 71.1 1.0 O A:LEU1721 3.8 75.5 1.0 N A:ILE1722 3.9 73.4 1.0 CA A:LEU1721 3.9 75.5 1.0 CD1 A:LEU1721 4.0 75.5 1.0 CG A:LEU1721 4.1 75.5 1.0 C27 A:MWV2301 4.1 69.8 1.0 NE2 A:GLN1718 4.3 71.8 1.0 CG2 A:VAL1725 4.4 81.6 1.0 CD1 A:PHE387 4.4 71.1 1.0 CA A:ILE1722 4.4 73.4 1.0 CG1 A:ILE1722 4.6 73.4 1.0 O A:GLN1718 4.7 71.8 1.0 CZ A:PHE387 4.8 71.1 1.0 CG A:ASN391 4.8 77.2 1.0 C25 A:MWV2301 4.9 69.8 1.0

L.He, Z.Yu, Z.Geng, Z.Huang, C.Zhang, Y.Dong, Y.Gao, Y.Wang, Q.Chen, L.Sun, X.Ma, B.Huang, X.Wang, Y.Zhao. Structure, Gating, and Pharmacology of Human Ca V 3.3 Channel. Nat Commun V. 13 2084 2022.
ISSN: ESSN 2041-1723
PubMed: 35440630
DOI: 10.1038/S41467-022-29728-0