Fluorine in PDB 7x01: Cryo-Em Structure of Chikungunya Virus Nonstructural Protein 1 with Inhibitor Fha

The structure of Cryo-Em Structure of Chikungunya Virus Nonstructural Protein 1 with Inhibitor Fha also contains other interesting chemical elements:

Zinc

(Zn)

12 atoms

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 12;

Binding sites:

The binding sites of Fluorine atom in the Cryo-Em Structure of Chikungunya Virus Nonstructural Protein 1 with Inhibitor Fha (pdb code 7x01). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 12 binding sites of Fluorine where determined in the Cryo-Em Structure of Chikungunya Virus Nonstructural Protein 1 with Inhibitor Fha, PDB code: 7x01:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Fluorine binding site 1 out of 12 in the Cryo-Em Structure of Chikungunya Virus Nonstructural Protein 1 with Inhibitor Fha


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Cryo-Em Structure of Chikungunya Virus Nonstructural Protein 1 with Inhibitor Fha within 5.0Å range: probe atom residue distance (Å) B Occ A:F1002 b:64.8 occ:1.00 F20 A:7XQ1002 0.0 64.8 1.0 C19 A:7XQ1002 1.4 64.8 1.0 C15 A:7XQ1002 2.2 64.8 1.0 C10 A:7XQ1002 2.5 64.8 1.0 C16 A:7XQ1002 2.5 64.8 1.0 N9 A:7XQ1002 2.8 64.8 1.0 C11 A:7XQ1002 2.9 64.8 1.0 C13 A:7XQ1002 2.9 64.8 1.0 C8 A:7XQ1002 3.1 64.8 1.0 C17 A:7XQ1002 3.7 64.8 1.0 C21 A:7XQ1002 3.8 64.8 1.0 N7 A:7XQ1002 4.1 64.8 1.0 O14 A:7XQ1002 4.2 64.8 1.0 O12 A:7XQ1002 4.4 64.8 1.0 C6 A:7XQ1002 4.5 64.8 1.0 CG1 A:VAL153 4.5 36.9 1.0 N1 A:7XQ1002 4.6 64.8 1.0 O18 A:7XQ1002 4.9 64.8 1.0 CB A:ALA155 4.9 29.2 1.0 CA A:VAL153 5.0 36.9 1.0 CG2 A:VAL153 5.0 36.9 1.0

Fluorine binding site 2 out of 12 in the Cryo-Em Structure of Chikungunya Virus Nonstructural Protein 1 with Inhibitor Fha


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Cryo-Em Structure of Chikungunya Virus Nonstructural Protein 1 with Inhibitor Fha within 5.0Å range: probe atom residue distance (Å) B Occ B:F1002 b:63.3 occ:1.00 F20 B:7XQ1002 0.0 63.3 1.0 C19 B:7XQ1002 1.4 63.3 1.0 C15 B:7XQ1002 2.2 63.3 1.0 C10 B:7XQ1002 2.5 63.3 1.0 C16 B:7XQ1002 2.5 63.3 1.0 N9 B:7XQ1002 2.8 63.3 1.0 C11 B:7XQ1002 2.9 63.3 1.0 C13 B:7XQ1002 3.0 63.3 1.0 C8 B:7XQ1002 3.1 63.3 1.0 C17 B:7XQ1002 3.7 63.3 1.0 C21 B:7XQ1002 3.8 63.3 1.0 N7 B:7XQ1002 4.1 63.3 1.0 O14 B:7XQ1002 4.2 63.3 1.0 O12 B:7XQ1002 4.4 63.3 1.0 C6 B:7XQ1002 4.5 63.3 1.0 CG1 B:VAL153 4.6 35.9 1.0 N1 B:7XQ1002 4.7 63.3 1.0 O18 B:7XQ1002 4.9 63.3 1.0 CB B:ALA155 4.9 28.9 1.0

Fluorine binding site 3 out of 12 in the Cryo-Em Structure of Chikungunya Virus Nonstructural Protein 1 with Inhibitor Fha


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Cryo-Em Structure of Chikungunya Virus Nonstructural Protein 1 with Inhibitor Fha within 5.0Å range: probe atom residue distance (Å) B Occ C:F1002 b:65.3 occ:1.00 F20 C:7XQ1002 0.0 65.3 1.0 C19 C:7XQ1002 1.4 65.3 1.0 C15 C:7XQ1002 2.2 65.3 1.0 C10 C:7XQ1002 2.5 65.3 1.0 C16 C:7XQ1002 2.5 65.3 1.0 N9 C:7XQ1002 2.8 65.3 1.0 C11 C:7XQ1002 3.0 65.3 1.0 C13 C:7XQ1002 3.0 65.3 1.0 C8 C:7XQ1002 3.1 65.3 1.0 C17 C:7XQ1002 3.7 65.3 1.0 C21 C:7XQ1002 3.8 65.3 1.0 N7 C:7XQ1002 4.1 65.3 1.0 O14 C:7XQ1002 4.2 65.3 1.0 O12 C:7XQ1002 4.4 65.3 1.0 C6 C:7XQ1002 4.5 65.3 1.0 CG1 C:VAL153 4.5 37.6 1.0 N1 C:7XQ1002 4.6 65.3 1.0 O18 C:7XQ1002 4.9 65.3 1.0 CB C:ALA155 4.9 29.0 1.0 CA C:VAL153 5.0 37.6 1.0 CG2 C:VAL153 5.0 37.6 1.0

Fluorine binding site 4 out of 12 in the Cryo-Em Structure of Chikungunya Virus Nonstructural Protein 1 with Inhibitor Fha


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Cryo-Em Structure of Chikungunya Virus Nonstructural Protein 1 with Inhibitor Fha within 5.0Å range: probe atom residue distance (Å) B Occ D:F1002 b:65.0 occ:1.00 F20 D:7XQ1002 0.0 65.0 1.0 C19 D:7XQ1002 1.4 65.0 1.0 C15 D:7XQ1002 2.2 65.0 1.0 C10 D:7XQ1002 2.5 65.0 1.0 C16 D:7XQ1002 2.5 65.0 1.0 N9 D:7XQ1002 2.8 65.0 1.0 C11 D:7XQ1002 2.9 65.0 1.0 C13 D:7XQ1002 2.9 65.0 1.0 C8 D:7XQ1002 3.1 65.0 1.0 C17 D:7XQ1002 3.7 65.0 1.0 C21 D:7XQ1002 3.8 65.0 1.0 N7 D:7XQ1002 4.1 65.0 1.0 O14 D:7XQ1002 4.2 65.0 1.0 O12 D:7XQ1002 4.4 65.0 1.0 C6 D:7XQ1002 4.5 65.0 1.0 CG1 D:VAL153 4.5 37.2 1.0 N1 D:7XQ1002 4.6 65.0 1.0 O18 D:7XQ1002 4.9 65.0 1.0 CB D:ALA155 4.9 29.5 1.0 CA D:VAL153 5.0 37.2 1.0 CG2 D:VAL153 5.0 37.2 1.0

Fluorine binding site 5 out of 12 in the Cryo-Em Structure of Chikungunya Virus Nonstructural Protein 1 with Inhibitor Fha


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of Cryo-Em Structure of Chikungunya Virus Nonstructural Protein 1 with Inhibitor Fha within 5.0Å range: probe atom residue distance (Å) B Occ E:F1002 b:64.2 occ:1.00 F20 E:7XQ1002 0.0 64.2 1.0 C19 E:7XQ1002 1.4 64.2 1.0 C15 E:7XQ1002 2.2 64.2 1.0 C10 E:7XQ1002 2.5 64.2 1.0 C16 E:7XQ1002 2.5 64.2 1.0 N9 E:7XQ1002 2.8 64.2 1.0 C11 E:7XQ1002 2.9 64.2 1.0 C13 E:7XQ1002 3.0 64.2 1.0 C8 E:7XQ1002 3.1 64.2 1.0 C17 E:7XQ1002 3.6 64.2 1.0 C21 E:7XQ1002 3.8 64.2 1.0 N7 E:7XQ1002 4.1 64.2 1.0 O14 E:7XQ1002 4.2 64.2 1.0 O12 E:7XQ1002 4.4 64.2 1.0 C6 E:7XQ1002 4.5 64.2 1.0 CG1 E:VAL153 4.6 35.5 1.0 N1 E:7XQ1002 4.7 64.2 1.0 O18 E:7XQ1002 4.9 64.2 1.0 CB E:ALA155 4.9 28.0 1.0

Fluorine binding site 6 out of 12 in the Cryo-Em Structure of Chikungunya Virus Nonstructural Protein 1 with Inhibitor Fha


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of Cryo-Em Structure of Chikungunya Virus Nonstructural Protein 1 with Inhibitor Fha within 5.0Å range: probe atom residue distance (Å) B Occ F:F1002 b:68.6 occ:1.00 F20 F:7XQ1002 0.0 68.6 1.0 C19 F:7XQ1002 1.4 68.6 1.0 C15 F:7XQ1002 2.2 68.6 1.0 C10 F:7XQ1002 2.5 68.6 1.0 C16 F:7XQ1002 2.5 68.6 1.0 N9 F:7XQ1002 2.9 68.6 1.0 C11 F:7XQ1002 2.9 68.6 1.0 C13 F:7XQ1002 3.0 68.6 1.0 C8 F:7XQ1002 3.1 68.6 1.0 C17 F:7XQ1002 3.7 68.6 1.0 C21 F:7XQ1002 3.8 68.6 1.0 N7 F:7XQ1002 4.1 68.6 1.0 O14 F:7XQ1002 4.2 68.6 1.0 O12 F:7XQ1002 4.4 68.6 1.0 C6 F:7XQ1002 4.5 68.6 1.0 CG1 F:VAL153 4.5 36.7 1.0 N1 F:7XQ1002 4.6 68.6 1.0 O18 F:7XQ1002 4.9 68.6 1.0 CB F:ALA155 4.9 28.9 1.0 CA F:VAL153 5.0 36.7 1.0

Fluorine binding site 7 out of 12 in the Cryo-Em Structure of Chikungunya Virus Nonstructural Protein 1 with Inhibitor Fha


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 7 of Cryo-Em Structure of Chikungunya Virus Nonstructural Protein 1 with Inhibitor Fha within 5.0Å range: probe atom residue distance (Å) B Occ G:F1002 b:64.4 occ:1.00 F20 G:7XQ1002 0.0 64.4 1.0 C19 G:7XQ1002 1.4 64.4 1.0 C15 G:7XQ1002 2.2 64.4 1.0 C10 G:7XQ1002 2.5 64.4 1.0 C16 G:7XQ1002 2.5 64.4 1.0 N9 G:7XQ1002 2.8 64.4 1.0 C11 G:7XQ1002 2.9 64.4 1.0 C13 G:7XQ1002 2.9 64.4 1.0 C8 G:7XQ1002 3.1 64.4 1.0 C17 G:7XQ1002 3.7 64.4 1.0 C21 G:7XQ1002 3.8 64.4 1.0 N7 G:7XQ1002 4.1 64.4 1.0 O14 G:7XQ1002 4.2 64.4 1.0 O12 G:7XQ1002 4.4 64.4 1.0 C6 G:7XQ1002 4.5 64.4 1.0 CG1 G:VAL153 4.6 36.7 1.0 N1 G:7XQ1002 4.6 64.4 1.0 O18 G:7XQ1002 4.9 64.4 1.0 CB G:ALA155 4.9 29.2 1.0 CA G:VAL153 5.0 36.7 1.0 CG2 G:VAL153 5.0 36.7 1.0

Fluorine binding site 8 out of 12 in the Cryo-Em Structure of Chikungunya Virus Nonstructural Protein 1 with Inhibitor Fha


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 8 of Cryo-Em Structure of Chikungunya Virus Nonstructural Protein 1 with Inhibitor Fha within 5.0Å range: probe atom residue distance (Å) B Occ H:F1002 b:63.0 occ:1.00 F20 H:7XQ1002 0.0 63.0 1.0 C19 H:7XQ1002 1.4 63.0 1.0 C15 H:7XQ1002 2.2 63.0 1.0 C10 H:7XQ1002 2.5 63.0 1.0 C16 H:7XQ1002 2.5 63.0 1.0 N9 H:7XQ1002 2.8 63.0 1.0 C11 H:7XQ1002 2.9 63.0 1.0 C13 H:7XQ1002 2.9 63.0 1.0 C8 H:7XQ1002 3.1 63.0 1.0 C17 H:7XQ1002 3.6 63.0 1.0 C21 H:7XQ1002 3.8 63.0 1.0 N7 H:7XQ1002 4.1 63.0 1.0 O14 H:7XQ1002 4.2 63.0 1.0 O12 H:7XQ1002 4.4 63.0 1.0 C6 H:7XQ1002 4.5 63.0 1.0 CG1 H:VAL153 4.6 34.9 1.0 N1 H:7XQ1002 4.7 63.0 1.0 O18 H:7XQ1002 4.8 63.0 1.0 CB H:ALA155 4.9 28.4 1.0

Fluorine binding site 9 out of 12 in the Cryo-Em Structure of Chikungunya Virus Nonstructural Protein 1 with Inhibitor Fha


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 9 of Cryo-Em Structure of Chikungunya Virus Nonstructural Protein 1 with Inhibitor Fha within 5.0Å range: probe atom residue distance (Å) B Occ I:F1002 b:67.0 occ:1.00 F20 I:7XQ1002 0.0 67.0 1.0 C19 I:7XQ1002 1.4 67.0 1.0 C15 I:7XQ1002 2.2 67.0 1.0 C10 I:7XQ1002 2.5 67.0 1.0 C16 I:7XQ1002 2.5 67.0 1.0 N9 I:7XQ1002 2.8 67.0 1.0 C11 I:7XQ1002 3.0 67.0 1.0 C13 I:7XQ1002 3.0 67.0 1.0 C8 I:7XQ1002 3.1 67.0 1.0 C17 I:7XQ1002 3.6 67.0 1.0 C21 I:7XQ1002 3.8 67.0 1.0 N7 I:7XQ1002 4.1 67.0 1.0 O14 I:7XQ1002 4.2 67.0 1.0 O12 I:7XQ1002 4.4 67.0 1.0 C6 I:7XQ1002 4.5 67.0 1.0 CG1 I:VAL153 4.5 37.9 1.0 N1 I:7XQ1002 4.6 67.0 1.0 O18 I:7XQ1002 4.8 67.0 1.0 CB I:ALA155 4.9 30.1 1.0 CA I:VAL153 5.0 37.9 1.0 CG2 I:VAL153 5.0 37.9 1.0

Fluorine binding site 10 out of 12 in the Cryo-Em Structure of Chikungunya Virus Nonstructural Protein 1 with Inhibitor Fha


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 10 of Cryo-Em Structure of Chikungunya Virus Nonstructural Protein 1 with Inhibitor Fha within 5.0Å range: probe atom residue distance (Å) B Occ J:F1002 b:64.7 occ:1.00 F20 J:7XQ1002 0.0 64.7 1.0 C19 J:7XQ1002 1.4 64.7 1.0 C15 J:7XQ1002 2.2 64.7 1.0 C10 J:7XQ1002 2.5 64.7 1.0 C16 J:7XQ1002 2.5 64.7 1.0 N9 J:7XQ1002 2.8 64.7 1.0 C11 J:7XQ1002 2.9 64.7 1.0 C13 J:7XQ1002 2.9 64.7 1.0 C8 J:7XQ1002 3.1 64.7 1.0 C17 J:7XQ1002 3.7 64.7 1.0 C21 J:7XQ1002 3.8 64.7 1.0 N7 J:7XQ1002 4.1 64.7 1.0 O14 J:7XQ1002 4.2 64.7 1.0 O12 J:7XQ1002 4.4 64.7 1.0 C6 J:7XQ1002 4.5 64.7 1.0 CG1 J:VAL153 4.6 37.3 1.0 N1 J:7XQ1002 4.6 64.7 1.0 O18 J:7XQ1002 4.9 64.7 1.0 CB J:ALA155 4.9 30.0 1.0 CA J:VAL153 5.0 37.3 1.0

K.Zhang, M.C.Y.Law, T.M.Nguyen, Y.B.Tan, M.Wirawan, Y.S.Law, L.S.Jeong, D.Luo. Molecular Basis of Specific Viral Rna Recognition and 5'-End Capping By the Chikungunya Virus NSP1. Cell Rep V. 40 11133 2022.
ISSN: ESSN 2211-1247
PubMed: 35905713
DOI: 10.1016/J.CELREP.2022.111133