Fluorine in PDB 7xmf: Cryo-Em Structure of Human NAV1.7/BETA1/BETA2-NAV1.7-IN2

The binding sites of Fluorine atom in the Cryo-Em Structure of Human NAV1.7/BETA1/BETA2-NAV1.7-IN2 (pdb code 7xmf). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Cryo-Em Structure of Human NAV1.7/BETA1/BETA2-NAV1.7-IN2, PDB code: 7xmf:

Fluorine binding site 1 out of 1 in the Cryo-Em Structure of Human NAV1.7/BETA1/BETA2-NAV1.7-IN2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Cryo-Em Structure of Human NAV1.7/BETA1/BETA2-NAV1.7-IN2 within 5.0Å range: probe atom residue distance (Å) B Occ A:F2303 b:20.0 occ:1.00 F01 A:G2W2303 0.0 20.0 1.0 C22 A:G2W2303 1.4 20.0 1.0 C19 A:G2W2303 2.5 20.0 1.0 C21 A:G2W2303 2.5 20.0 1.0 CD1 A:ILE394 2.8 38.4 1.0 O A:THR359 3.4 37.5 1.0 C16 A:G2W2303 3.9 20.0 1.0 C15 A:G2W2303 3.9 20.0 1.0 C A:THR359 3.9 37.5 1.0 CG1 A:ILE394 4.1 38.4 1.0 CA A:THR359 4.1 37.5 1.0 C13 A:G2W2303 4.4 20.0 1.0 O A:MET358 4.5 39.9 1.0 CG2 A:ILE394 4.7 38.4 1.0 CB A:GLN360 4.8 38.1 1.0 N A:GLN360 4.8 38.1 1.0 CB A:THR359 4.9 37.5 1.0 CD A:GLN360 4.9 38.1 1.0 CB A:ILE394 5.0 38.4 1.0 C30 A:G2W2303 5.0 20.0 1.0

J.Zhang, Y.Shi, Z.Huang, Y.Li, B.Yang, J.Gong, D.Jiang. Structural Basis For Na V 1.7 Inhibition By Pore Blockers. Nat.Struct.Mol.Biol. V. 29 1208 2022.
ISSN: ESSN 1545-9985
PubMed: 36424527
DOI: 10.1038/S41594-022-00860-1