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Fluorine in PDB 7y4u: Crystal Structure of Cmet Kinase Domain Bound By Compound 9YEnzymatic activity of Crystal Structure of Cmet Kinase Domain Bound By Compound 9Y
All present enzymatic activity of Crystal Structure of Cmet Kinase Domain Bound By Compound 9Y:
2.7.10.1; Protein crystallography data
The structure of Crystal Structure of Cmet Kinase Domain Bound By Compound 9Y, PDB code: 7y4u
was solved by
L.Z.Qu,
Y.H.Chen,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Cmet Kinase Domain Bound By Compound 9Y
(pdb code 7y4u). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Crystal Structure of Cmet Kinase Domain Bound By Compound 9Y, PDB code: 7y4u: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 7y4uGo back to Fluorine Binding Sites List in 7y4u
Fluorine binding site 1 out
of 3 in the Crystal Structure of Cmet Kinase Domain Bound By Compound 9Y
Mono view Stereo pair view
Fluorine binding site 2 out of 3 in 7y4uGo back to Fluorine Binding Sites List in 7y4u
Fluorine binding site 2 out
of 3 in the Crystal Structure of Cmet Kinase Domain Bound By Compound 9Y
Mono view Stereo pair view
Fluorine binding site 3 out of 3 in 7y4uGo back to Fluorine Binding Sites List in 7y4u
Fluorine binding site 3 out
of 3 in the Crystal Structure of Cmet Kinase Domain Bound By Compound 9Y
Mono view Stereo pair view
Reference:
C.Wang,
J.Li,
L.Qu,
X.Tang,
X.Song,
F.Yang,
X.Chen,
Q.Lin,
W.Lin,
Y.Zhou,
Z.Tu,
Y.Chen,
Z.Zhang,
X.Lu.
Discovery of D6808, A Highly Selective and Potent Macrocyclic C-Met Inhibitor For Gastric Cancer Harboring Met Gene Alteration Treatment. J.Med.Chem. V. 65 15140 2022.
Page generated: Wed Apr 5 01:53:35 2023
ISSN: ISSN 0022-2623 PubMed: 36355693 DOI: 10.1021/ACS.JMEDCHEM.2C00981 |
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