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Atomistry » Fluorine » PDB 7ymk-7zej » 7z7d | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 7ymk-7zej » 7z7d » |
Fluorine in PDB 7z7d: Tubulin-Todalam-Vinblastine-ComplexProtein crystallography data
The structure of Tubulin-Todalam-Vinblastine-Complex, PDB code: 7z7d
was solved by
T.Muehlethaler,
L.Milanos,
J.A.Ortega,
T.B.Blum,
D.Gioia,
B.Roy,
A.E.Prota,
A.Cavalli,
M.O.Steinmetz,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7z7d:
The structure of Tubulin-Todalam-Vinblastine-Complex also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Tubulin-Todalam-Vinblastine-Complex
(pdb code 7z7d). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Tubulin-Todalam-Vinblastine-Complex, PDB code: 7z7d: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 7z7dGo back to Fluorine Binding Sites List in 7z7d
Fluorine binding site 1 out
of 3 in the Tubulin-Todalam-Vinblastine-Complex
Mono view Stereo pair view
Fluorine binding site 2 out of 3 in 7z7dGo back to Fluorine Binding Sites List in 7z7d
Fluorine binding site 2 out
of 3 in the Tubulin-Todalam-Vinblastine-Complex
Mono view Stereo pair view
Fluorine binding site 3 out of 3 in 7z7dGo back to Fluorine Binding Sites List in 7z7d
Fluorine binding site 3 out
of 3 in the Tubulin-Todalam-Vinblastine-Complex
Mono view Stereo pair view
Reference:
T.Muhlethaler,
L.Milanos,
J.A.Ortega,
T.B.Blum,
D.Gioia,
B.Roy,
A.E.Prota,
A.Cavalli,
M.O.Steinmetz.
Rational Design of A Novel Tubulin Inhibitor with A Unique Mechanism of Action. Angew.Chem.Int.Ed.Engl. V. 61 04052 2022.
Page generated: Fri Aug 2 16:07:18 2024
ISSN: ESSN 1521-3773 PubMed: 35404502 DOI: 10.1002/ANIE.202204052 |
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