Fluorine in PDB 7z87: Dna-Pk in the Active State

All present enzymatic activity of Dna-Pk in the Active State:
2.7.11.1;

The structure of Dna-Pk in the Active State also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Fluorine atom in the Dna-Pk in the Active State (pdb code 7z87). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Dna-Pk in the Active State, PDB code: 7z87:

Fluorine binding site 1 out of 1 in the Dna-Pk in the Active State


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Dna-Pk in the Active State within 5.0Å range: probe atom residue distance (Å) B Occ A:F4201 b:100.7 occ:1.00 F32 A:1IX4201 0.0 100.7 1.0 C13 A:1IX4201 1.3 100.7 1.0 C14 A:1IX4201 2.3 100.7 1.0 C12 A:1IX4201 2.4 100.7 1.0 C16 A:1IX4201 2.8 100.7 1.0 NZ A:LYS3753 2.9 115.2 1.0 N17 A:1IX4201 3.0 100.7 1.0 CE A:LYS3753 3.4 115.2 1.0 C15 A:1IX4201 3.6 100.7 1.0 CG A:PRO3735 3.7 122.1 1.0 C11 A:1IX4201 3.7 100.7 1.0 C21 A:1IX4201 3.9 100.7 1.0 C18 A:1IX4201 4.1 100.7 1.0 C10 A:1IX4201 4.1 100.7 1.0 CD2 A:LEU3751 4.2 99.5 1.0 CB A:PRO3735 4.4 122.1 1.0 C22 A:1IX4201 4.5 100.7 1.0 CE A:MET3729 4.6 123.8 1.0 CD A:PRO3735 4.6 122.1 1.0 OD2 A:ASP3941 4.7 92.9 1.0 SD A:MET3729 4.7 123.8 1.0 CD A:LYS3753 4.8 115.2 1.0 C20 A:1IX4201 4.8 100.7 1.0 N19 A:1IX4201 4.8 100.7 1.0 OG A:SER3731 5.0 134.6 1.0 CG A:LEU3751 5.0 99.5 1.0

S.Liang, T.L.Blundell. Human Dna-Dependent Protein Kinase Activation Mechanism. Nat.Struct.Mol.Biol. 2023.
ISSN: ESSN 1545-9985
PubMed: 36604499
DOI: 10.1038/S41594-022-00881-W