Fluorine in PDB 8ahf: Pac-Fragmentdel: Photoactivated Covalent Capture of Dna Encoded Fragments For Hit Discovery
Enzymatic activity of Pac-Fragmentdel: Photoactivated Covalent Capture of Dna Encoded Fragments For Hit Discovery
All present enzymatic activity of Pac-Fragmentdel: Photoactivated Covalent Capture of Dna Encoded Fragments For Hit Discovery:
5.1.3.14;
5.1.3.14;
Protein crystallography data
The structure of Pac-Fragmentdel: Photoactivated Covalent Capture of Dna Encoded Fragments For Hit Discovery, PDB code: 8ahf
was solved by
L.M.Baker,
J.B.Murray,
R.E.Hubbard,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 85.17 / 2.27 |
| Space group | P 41 21 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 109.315, 109.315, 135.866, 90, 90, 90 |
| R / Rfree (%) | 17.7 / 23.8 |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Pac-Fragmentdel: Photoactivated Covalent Capture of Dna Encoded Fragments For Hit Discovery
(pdb code 8ahf). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the Pac-Fragmentdel: Photoactivated Covalent Capture of Dna Encoded Fragments For Hit Discovery, PDB code: 8ahf:
Jump to Fluorine binding site number: 1; 2; 3; 4;
In total 4 binding sites of Fluorine where determined in the Pac-Fragmentdel: Photoactivated Covalent Capture of Dna Encoded Fragments For Hit Discovery, PDB code: 8ahf:
Jump to Fluorine binding site number: 1; 2; 3; 4;
Fluorine binding site 1 out of 4 in 8ahf
Go back to
Fluorine Binding Sites List in 8ahf
Fluorine binding site 1 out
of 4 in the Pac-Fragmentdel: Photoactivated Covalent Capture of Dna Encoded Fragments For Hit Discovery
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Pac-Fragmentdel: Photoactivated Covalent Capture of Dna Encoded Fragments For Hit Discovery within 5.0Å range:
|
Fluorine binding site 2 out of 4 in 8ahf
Go back to
Fluorine Binding Sites List in 8ahf
Fluorine binding site 2 out
of 4 in the Pac-Fragmentdel: Photoactivated Covalent Capture of Dna Encoded Fragments For Hit Discovery
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Pac-Fragmentdel: Photoactivated Covalent Capture of Dna Encoded Fragments For Hit Discovery within 5.0Å range:
|
Fluorine binding site 3 out of 4 in 8ahf
Go back to
Fluorine Binding Sites List in 8ahf
Fluorine binding site 3 out
of 4 in the Pac-Fragmentdel: Photoactivated Covalent Capture of Dna Encoded Fragments For Hit Discovery
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Pac-Fragmentdel: Photoactivated Covalent Capture of Dna Encoded Fragments For Hit Discovery within 5.0Å range:
|
Fluorine binding site 4 out of 4 in 8ahf
Go back to
Fluorine Binding Sites List in 8ahf
Fluorine binding site 4 out
of 4 in the Pac-Fragmentdel: Photoactivated Covalent Capture of Dna Encoded Fragments For Hit Discovery
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 4 of Pac-Fragmentdel: Photoactivated Covalent Capture of Dna Encoded Fragments For Hit Discovery within 5.0Å range:
|
Reference:
H.Ma,
J.B.Murray,
H.Luo,
X.Cheng,
Q.Chen,
C.Song,
C.Duan,
P.Tan,
L.Zhang,
J.Liu,
B.A.Morgan,
J.Li,
J.Wan,
L.M.Baker,
W.Finnie,
L.Guetzoyan,
R.Harris,
N.Hendrickson,
N.Matassova,
H.Simmonite,
J.Smith,
R.E.Hubbard,
G.Liu.
Pac-Fragmentdel - Photoactivated Covalent Capture of Dna-Encoded Fragments For Hit Discovery. Rsc Med Chem V. 13 1341 2022.
ISSN: ESSN 2632-8682
PubMed: 36426238
DOI: 10.1039/D2MD00197G
Page generated: Fri Aug 2 16:30:20 2024
ISSN: ESSN 2632-8682
PubMed: 36426238
DOI: 10.1039/D2MD00197G
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