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Atomistry » Fluorine » PDB 8a19-8azl » 8alt » |
Fluorine in PDB 8alt: Small Molecular Stabilizer For Eralpha and 14-3-3 (1075311)Protein crystallography data
The structure of Small Molecular Stabilizer For Eralpha and 14-3-3 (1075311), PDB code: 8alt
was solved by
E.J.Visser,
E.M.V.Vandenboorn,
C.Ottmann,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8alt:
The structure of Small Molecular Stabilizer For Eralpha and 14-3-3 (1075311) also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Small Molecular Stabilizer For Eralpha and 14-3-3 (1075311)
(pdb code 8alt). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Small Molecular Stabilizer For Eralpha and 14-3-3 (1075311), PDB code: 8alt: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 8altGo back to Fluorine Binding Sites List in 8alt
Fluorine binding site 1 out
of 2 in the Small Molecular Stabilizer For Eralpha and 14-3-3 (1075311)
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 8altGo back to Fluorine Binding Sites List in 8alt
Fluorine binding site 2 out
of 2 in the Small Molecular Stabilizer For Eralpha and 14-3-3 (1075311)
Mono view Stereo pair view
Reference:
M.Konstantinidou,
E.J.Visser,
E.Vandenboorn,
S.Chen,
P.Jaishankar,
M.Overmans,
S.Dutta,
R.J.Neitz,
A.R.Renslo,
C.Ottmann,
L.Brunsveld,
M.R.Arkin.
Structure-Based Optimization of Covalent, Small-Molecule Stabilizers of the 14-3-3 Sigma /Er Alpha Protein-Protein Interaction From Nonselective Fragments. J.Am.Chem.Soc. 2023.
Page generated: Fri Aug 2 16:31:11 2024
ISSN: ESSN 1520-5126 PubMed: 37676236 DOI: 10.1021/JACS.3C05161 |
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