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Fluorine in PDB 8ans: Crystal Structure of D1228V C-Met Bound By Compound 1.Enzymatic activity of Crystal Structure of D1228V C-Met Bound By Compound 1.
All present enzymatic activity of Crystal Structure of D1228V C-Met Bound By Compound 1.:
2.7.10.1; Protein crystallography data
The structure of Crystal Structure of D1228V C-Met Bound By Compound 1., PDB code: 8ans
was solved by
G.W.Collie,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of D1228V C-Met Bound By Compound 1.
(pdb code 8ans). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Crystal Structure of D1228V C-Met Bound By Compound 1., PDB code: 8ans: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 8ansGo back to Fluorine Binding Sites List in 8ans
Fluorine binding site 1 out
of 2 in the Crystal Structure of D1228V C-Met Bound By Compound 1.
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 8ansGo back to Fluorine Binding Sites List in 8ans
Fluorine binding site 2 out
of 2 in the Crystal Structure of D1228V C-Met Bound By Compound 1.
Mono view Stereo pair view
Reference:
G.W.Collie,
L.Barlind,
S.Bazzaz,
U.Borjesson,
I.L.Dale,
J.S.Disch,
S.Habeshian,
R.Jetson,
P.Khurana,
A.Madin,
I.N.Michaelides,
L.Peng,
A.Snijder,
C.J.Stubbs.
Discovery of A Selective C-Met Inhibitor with A Novel Binding Mode. Bioorg.Med.Chem.Lett. V. 75 28948 2022.
Page generated: Wed Apr 5 02:04:19 2023
ISSN: ESSN 1464-3405 PubMed: 35987508 DOI: 10.1016/J.BMCL.2022.128948 |
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