Fluorine in PDB 8auu: Human Aldose Reductase Mutant A299G in Complex with A Ligand with An Idd Structure ({5-Fluoro-2-[(3-Nitrobenzyl)Carbamoyl]Phenoxy}Acetic Acid)

Enzymatic activity of Human Aldose Reductase Mutant A299G in Complex with A Ligand with An Idd Structure ({5-Fluoro-2-[(3-Nitrobenzyl)Carbamoyl]Phenoxy}Acetic Acid)

Protein crystallography data

Fluorine Binding Sites:

Fluorine binding site 1 out of 1 in 8auu

Fluorine Binding Sites List in 8auu

Fluorine binding site 1 out of 1 in the Human Aldose Reductase Mutant A299G in Complex with A Ligand with An Idd Structure ({5-Fluoro-2-[(3-Nitrobenzyl)Carbamoyl]Phenoxy}Acetic Acid)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Human Aldose Reductase Mutant A299G in Complex with A Ligand with An Idd Structure ({5-Fluoro-2-[(3-Nitrobenzyl)Carbamoyl]Phenoxy}Acetic Acid) within 5.0Å range: probe atom residue distance (Å) B Occ A:F402 b:7.8 occ:1.00 F27 A:30L402 0.0 7.8 1.0 C26 A:30L402 1.4 6.8 1.0 C28 A:30L402 2.3 5.8 1.0 C24 A:30L402 2.4 7.6 1.0 HG13 A:VAL47 2.8 5.6 1.0 HD1 A:TYR48 2.8 4.8 1.0 O A:VAL47 3.2 4.6 1.0 HG22 A:VAL47 3.2 6.0 1.0 HA A:TYR48 3.2 4.7 1.0 HE1 A:TRP20 3.3 5.8 1.0 O A:HOH887 3.4 9.0 1.0 O A:HOH711 3.5 12.6 1.0 C30 A:30L402 3.6 5.8 1.0 C22 A:30L402 3.6 7.5 1.0 O A:HOH562 3.6 6.4 1.0 HD1 A:TRP20 3.6 5.5 1.0 CD1 A:TYR48 3.7 4.0 1.0 CG1 A:VAL47 3.7 4.6 1.0 NE1 A:TRP20 3.7 4.8 1.0 C A:VAL47 3.7 4.1 1.0 CD1 A:TRP20 3.9 4.6 1.0 HE1 A:TYR48 3.9 4.7 1.0 CG2 A:VAL47 4.0 5.0 1.0 CA A:TYR48 4.1 3.9 1.0 HG11 A:VAL47 4.1 5.6 1.0 C21 A:30L402 4.1 7.0 1.0 N A:TYR48 4.1 3.7 1.0 HG21 A:VAL47 4.2 6.0 1.0 CE1 A:TYR48 4.2 3.9 1.0 HG12 A:VAL47 4.3 5.6 1.0 CB A:VAL47 4.3 4.5 1.0 CA A:VAL47 4.6 4.1 1.0 O A:HOH923 4.7 8.7 1.0 CG A:TYR48 4.7 3.9 1.0 CE2 A:TRP20 4.7 4.9 1.0 O31 A:30L402 4.7 5.7 1.0 H A:TYR48 4.8 4.5 1.0 HG23 A:VAL47 4.8 6.0 1.0 O A:HOH652 4.9 7.8 1.0 CB A:TYR48 4.9 4.0 1.0 CG A:TRP20 4.9 4.5 1.0

Reference: