Fluorine in PDB 8c1r: Resting State Homomeric GLUA2 F231A Mutant Ampa Receptor in Complex with Tarp Gamma-2

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>>> Page 1 <<< Page 2, Binding sites: 11 - 12;

Binding sites:

The binding sites of Fluorine atom in the Resting State Homomeric GLUA2 F231A Mutant Ampa Receptor in Complex with Tarp Gamma-2 (pdb code 8c1r). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 12 binding sites of Fluorine where determined in the Resting State Homomeric GLUA2 F231A Mutant Ampa Receptor in Complex with Tarp Gamma-2, PDB code: 8c1r:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Fluorine binding site 1 out of 12 in the Resting State Homomeric GLUA2 F231A Mutant Ampa Receptor in Complex with Tarp Gamma-2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Resting State Homomeric GLUA2 F231A Mutant Ampa Receptor in Complex with Tarp Gamma-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:F901 b:130.8 occ:1.00 FAF A:ZK1901 0.0 130.8 1.0 CAZ A:ZK1901 1.3 118.6 1.0 FAH A:ZK1901 2.1 126.4 1.0 FAG A:ZK1901 2.1 114.4 1.0 CAS A:ZK1901 2.3 103.9 1.0 OH A:TYR732 2.6 106.2 1.0 CAJ A:ZK1901 2.8 112.3 1.0 CAR A:ZK1901 3.5 99.2 1.0 OE2 A:GLU705 3.5 192.9 1.0 CZ A:TYR732 3.6 98.1 1.0 CAM A:ZK1901 3.8 136.3 1.0 NAX A:ZK1901 3.9 123.5 1.0 CE2 A:TYR732 4.0 79.3 1.0 OG1 A:THR707 4.0 84.4 1.0 CD A:GLU705 4.1 202.3 1.0 CAV A:ZK1901 4.2 107.9 1.0 CE2 A:TYR405 4.2 95.8 1.0 CAN A:ZK1901 4.6 140.3 1.0 CAI A:ZK1901 4.6 116.9 1.0 CB A:GLU705 4.7 109.1 1.0 OH A:TYR405 4.7 82.1 1.0 CE A:MET708 4.7 144.6 1.0 CE1 A:TYR732 4.7 97.3 1.0 OE1 A:GLU705 4.7 233.2 1.0 CG A:GLU705 4.8 150.9 1.0 CB A:PRO478 4.8 103.1 1.0 CZ A:TYR405 4.8 97.9 1.0 CAW A:ZK1901 4.9 104.5 1.0 CG A:PRO478 5.0 110.7 1.0

Fluorine binding site 2 out of 12 in the Resting State Homomeric GLUA2 F231A Mutant Ampa Receptor in Complex with Tarp Gamma-2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Resting State Homomeric GLUA2 F231A Mutant Ampa Receptor in Complex with Tarp Gamma-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:F901 b:114.4 occ:1.00 FAG A:ZK1901 0.0 114.4 1.0 CAZ A:ZK1901 1.3 118.6 1.0 FAH A:ZK1901 2.1 126.4 1.0 FAF A:ZK1901 2.1 130.8 1.0 CAM A:ZK1901 2.3 136.3 1.0 CAS A:ZK1901 2.3 103.9 1.0 NAX A:ZK1901 2.4 123.5 1.0 CAR A:ZK1901 2.7 99.2 1.0 CAN A:ZK1901 2.7 140.3 1.0 CAK A:ZK1901 3.4 141.8 1.0 CAJ A:ZK1901 3.6 112.3 1.0 CE A:MET708 3.6 144.6 1.0 CAL A:ZK1901 3.7 148.9 1.0 OAQ A:ZK1901 4.1 157.2 1.0 CAI A:ZK1901 4.1 116.9 1.0 CB A:MET708 4.3 112.7 1.0 OE2 A:GLU402 4.4 212.4 1.0 CG A:GLU402 4.5 171.0 1.0 OH A:TYR732 4.5 106.2 1.0 CG A:MET708 4.5 130.3 1.0 OE2 A:GLU705 4.6 192.9 1.0 CD A:GLU402 4.6 184.1 1.0 CD A:GLU705 4.7 202.3 1.0 CAV A:ZK1901 4.7 107.9 1.0 SD A:MET708 4.8 162.9 1.0 OH A:TYR450 4.8 150.2 1.0 CAW A:ZK1901 4.9 104.5 1.0

Fluorine binding site 3 out of 12 in the Resting State Homomeric GLUA2 F231A Mutant Ampa Receptor in Complex with Tarp Gamma-2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Resting State Homomeric GLUA2 F231A Mutant Ampa Receptor in Complex with Tarp Gamma-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:F901 b:126.4 occ:1.00 FAH A:ZK1901 0.0 126.4 1.0 CAZ A:ZK1901 1.3 118.6 1.0 FAG A:ZK1901 2.1 114.4 1.0 FAF A:ZK1901 2.1 130.8 1.0 CAS A:ZK1901 2.3 103.9 1.0 CAJ A:ZK1901 3.0 112.3 1.0 CAR A:ZK1901 3.4 99.2 1.0 CG A:GLU402 3.4 171.0 1.0 OH A:TYR450 3.5 150.2 1.0 CAN A:ZK1901 3.7 140.3 1.0 NAX A:ZK1901 3.7 123.5 1.0 CE2 A:TYR405 3.9 95.8 1.0 CG A:PRO478 4.0 110.7 1.0 CD2 A:TYR405 4.1 109.6 1.0 CAM A:ZK1901 4.1 136.3 1.0 CD A:GLU402 4.1 184.1 1.0 CAV A:ZK1901 4.3 107.9 1.0 CE A:MET708 4.3 144.6 1.0 OH A:TYR732 4.3 106.2 1.0 CB A:GLU402 4.4 160.8 1.0 OE2 A:GLU402 4.5 212.4 1.0 CB A:PRO478 4.5 103.1 1.0 CAI A:ZK1901 4.5 116.9 1.0 CZ A:TYR450 4.5 145.1 1.0 OE1 A:GLU402 4.8 203.6 1.0 CAW A:ZK1901 4.9 104.5 1.0 CAL A:ZK1901 4.9 148.9 1.0 CZ A:TYR405 4.9 97.9 1.0

Fluorine binding site 4 out of 12 in the Resting State Homomeric GLUA2 F231A Mutant Ampa Receptor in Complex with Tarp Gamma-2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Resting State Homomeric GLUA2 F231A Mutant Ampa Receptor in Complex with Tarp Gamma-2 within 5.0Å range: probe atom residue distance (Å) B Occ B:F901 b:148.4 occ:1.00 FAF B:ZK1901 0.0 148.4 1.0 CAZ B:ZK1901 1.3 136.8 1.0 FAG B:ZK1901 2.1 150.2 1.0 FAH B:ZK1901 2.1 144.9 1.0 CAS B:ZK1901 2.3 116.0 1.0 OH B:TYR732 2.7 113.1 1.0 CAJ B:ZK1901 3.0 132.3 1.0 CAR B:ZK1901 3.4 127.6 1.0 CZ B:TYR732 3.5 126.9 1.0 NAX B:ZK1901 3.7 143.7 1.0 OG1 B:THR707 3.7 103.1 1.0 CE2 B:TYR732 3.7 101.9 1.0 OH B:TYR405 4.2 162.6 1.0 CB B:PRO478 4.2 152.8 1.0 CE2 B:TYR405 4.2 172.8 1.0 CAV B:ZK1901 4.3 135.0 1.0 CG B:PRO478 4.5 161.1 1.0 CAN B:ZK1901 4.5 176.4 1.0 CAI B:ZK1901 4.6 138.4 1.0 CZ B:TYR405 4.7 147.4 1.0 CE B:MET708 4.7 149.8 1.0 CAM B:ZK1901 4.7 160.4 1.0 CE1 B:TYR732 4.8 125.0 1.0 CAW B:ZK1901 5.0 115.0 1.0 CB B:THR707 5.0 129.0 1.0 CB B:GLU705 5.0 139.0 1.0

Fluorine binding site 5 out of 12 in the Resting State Homomeric GLUA2 F231A Mutant Ampa Receptor in Complex with Tarp Gamma-2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of Resting State Homomeric GLUA2 F231A Mutant Ampa Receptor in Complex with Tarp Gamma-2 within 5.0Å range: probe atom residue distance (Å) B Occ B:F901 b:150.2 occ:1.00 FAG B:ZK1901 0.0 150.2 1.0 CAZ B:ZK1901 1.3 136.8 1.0 FAF B:ZK1901 2.1 148.4 1.0 FAH B:ZK1901 2.1 144.9 1.0 CAS B:ZK1901 2.3 116.0 1.0 NAX B:ZK1901 2.4 143.7 1.0 CAN B:ZK1901 2.7 176.4 1.0 CAR B:ZK1901 2.7 127.6 1.0 CAL B:ZK1901 3.3 182.5 1.0 CAM B:ZK1901 3.5 160.4 1.0 CE B:MET708 3.6 149.8 1.0 CAJ B:ZK1901 3.6 132.3 1.0 CAI B:ZK1901 4.1 138.4 1.0 CB B:MET708 4.4 115.9 1.0 OAQ B:ZK1901 4.5 208.6 1.0 CG B:MET708 4.5 142.0 1.0 OH B:TYR450 4.5 194.0 1.0 CAK B:ZK1901 4.6 184.8 1.0 OH B:TYR732 4.6 113.1 1.0 OE1 B:GLU402 4.6 213.6 1.0 CAV B:ZK1901 4.8 135.0 1.0 SD B:MET708 4.8 189.7 1.0 CD B:GLU402 4.8 216.4 1.0 CE2 B:TYR405 4.8 172.8 1.0 CG B:GLU402 5.0 215.8 1.0 CAW B:ZK1901 5.0 115.0 1.0

Fluorine binding site 6 out of 12 in the Resting State Homomeric GLUA2 F231A Mutant Ampa Receptor in Complex with Tarp Gamma-2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of Resting State Homomeric GLUA2 F231A Mutant Ampa Receptor in Complex with Tarp Gamma-2 within 5.0Å range: probe atom residue distance (Å) B Occ B:F901 b:144.9 occ:1.00 FAH B:ZK1901 0.0 144.9 1.0 CAZ B:ZK1901 1.3 136.8 1.0 FAF B:ZK1901 2.1 148.4 1.0 FAG B:ZK1901 2.1 150.2 1.0 CAS B:ZK1901 2.4 116.0 1.0 CAJ B:ZK1901 2.9 132.3 1.0 CG B:PRO478 3.4 161.1 1.0 CB B:PRO478 3.4 152.8 1.0 CAR B:ZK1901 3.5 127.6 1.0 CE2 B:TYR405 3.6 172.8 1.0 NAX B:ZK1901 3.9 143.7 1.0 OH B:TYR450 4.0 194.0 1.0 CAN B:ZK1901 4.0 176.4 1.0 CG B:GLU402 4.0 215.8 1.0 CB B:GLU402 4.1 213.1 1.0 CD2 B:TYR405 4.1 171.7 1.0 CAV B:ZK1901 4.3 135.0 1.0 OH B:TYR732 4.3 113.1 1.0 CZ B:TYR405 4.5 147.4 1.0 CD B:GLU402 4.5 216.4 1.0 CZ B:TYR450 4.6 198.3 1.0 CE1 B:TYR450 4.6 179.1 1.0 CE B:MET708 4.6 149.8 1.0 CAI B:ZK1901 4.6 138.4 1.0 OH B:TYR405 4.7 162.6 1.0 CD B:PRO478 4.7 175.0 1.0 OE1 B:GLU402 4.7 213.6 1.0 CE2 B:TYR732 4.8 101.9 1.0 CZ B:TYR732 4.8 126.9 1.0 CA B:PRO478 4.9 140.9 1.0 CAW B:ZK1901 5.0 115.0 1.0

Fluorine binding site 7 out of 12 in the Resting State Homomeric GLUA2 F231A Mutant Ampa Receptor in Complex with Tarp Gamma-2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 7 of Resting State Homomeric GLUA2 F231A Mutant Ampa Receptor in Complex with Tarp Gamma-2 within 5.0Å range: probe atom residue distance (Å) B Occ C:F901 b:101.5 occ:1.00 FAF C:ZK1901 0.0 101.5 1.0 CAZ C:ZK1901 1.3 131.8 1.0 FAG C:ZK1901 2.1 158.4 1.0 FAH C:ZK1901 2.1 110.1 1.0 CAS C:ZK1901 2.4 107.5 1.0 CAJ C:ZK1901 2.8 100.7 1.0 CE2 C:TYR405 3.2 115.1 1.0 CG C:PRO478 3.2 113.0 1.0 CB C:PRO478 3.3 123.0 1.0 CAR C:ZK1901 3.6 114.0 1.0 CD2 C:TYR405 3.7 121.6 1.0 CZ C:TYR405 3.7 120.2 1.0 OH C:TYR732 3.8 82.3 1.0 OH C:TYR405 3.9 131.2 1.0 NAX C:ZK1901 4.0 127.8 1.0 CAV C:ZK1901 4.2 116.2 1.0 CZ C:TYR732 4.2 100.2 1.0 OH C:TYR450 4.2 129.5 1.0 CE2 C:TYR732 4.2 83.4 1.0 CG C:GLU402 4.4 171.3 1.0 O C:PRO478 4.5 107.5 1.0 CAN C:ZK1901 4.5 163.0 1.0 CG C:TYR405 4.6 124.9 1.0 CE C:MET708 4.6 129.9 1.0 CE1 C:TYR405 4.6 108.8 1.0 CD C:PRO478 4.7 107.5 1.0 CB C:GLU402 4.7 155.1 1.0 CD C:GLU402 4.7 198.0 1.0 CAI C:ZK1901 4.7 124.8 1.0 CA C:PRO478 4.7 110.5 1.0 OE1 C:GLU402 4.8 195.1 1.0 CAW C:ZK1901 5.0 111.8 1.0

Fluorine binding site 8 out of 12 in the Resting State Homomeric GLUA2 F231A Mutant Ampa Receptor in Complex with Tarp Gamma-2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 8 of Resting State Homomeric GLUA2 F231A Mutant Ampa Receptor in Complex with Tarp Gamma-2 within 5.0Å range: probe atom residue distance (Å) B Occ C:F901 b:158.4 occ:1.00 FAG C:ZK1901 0.0 158.4 1.0 CAZ C:ZK1901 1.3 131.8 1.0 FAF C:ZK1901 2.1 101.5 1.0 FAH C:ZK1901 2.1 110.1 1.0 CAS C:ZK1901 2.3 107.5 1.0 OH C:TYR732 2.8 82.3 1.0 CAJ C:ZK1901 3.2 100.7 1.0 CAR C:ZK1901 3.3 114.0 1.0 NAX C:ZK1901 3.4 127.8 1.0 CZ C:TYR732 3.9 100.2 1.0 OG1 C:THR707 4.0 113.5 1.0 OH C:TYR405 4.0 131.2 1.0 CE C:MET708 4.1 129.9 1.0 CE2 C:TYR405 4.1 115.1 1.0 CAM C:ZK1901 4.2 140.5 1.0 CE2 C:TYR732 4.2 83.4 1.0 CG C:GLU705 4.2 207.1 1.0 CB C:GLU705 4.3 155.6 1.0 CAV C:ZK1901 4.4 116.2 1.0 CAN C:ZK1901 4.4 163.0 1.0 CZ C:TYR405 4.5 120.2 1.0 CAI C:ZK1901 4.5 124.8 1.0 CB C:MET708 4.7 152.6 1.0 OE2 C:GLU705 4.7 211.7 1.0 CB C:PRO478 4.9 123.0 1.0 CD C:GLU705 4.9 245.1 1.0 CAW C:ZK1901 5.0 111.8 1.0

Fluorine binding site 9 out of 12 in the Resting State Homomeric GLUA2 F231A Mutant Ampa Receptor in Complex with Tarp Gamma-2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 9 of Resting State Homomeric GLUA2 F231A Mutant Ampa Receptor in Complex with Tarp Gamma-2 within 5.0Å range: probe atom residue distance (Å) B Occ C:F901 b:110.1 occ:1.00 FAH C:ZK1901 0.0 110.1 1.0 CAZ C:ZK1901 1.3 131.8 1.0 FAF C:ZK1901 2.1 101.5 1.0 FAG C:ZK1901 2.1 158.4 1.0 CAS C:ZK1901 2.4 107.5 1.0 NAX C:ZK1901 2.5 127.8 1.0 CAR C:ZK1901 2.8 114.0 1.0 CAN C:ZK1901 2.8 163.0 1.0 CE C:MET708 3.5 129.9 1.0 CAJ C:ZK1901 3.6 100.7 1.0 CAM C:ZK1901 3.7 140.5 1.0 OE1 C:GLU402 3.7 195.1 1.0 CD C:GLU402 4.0 198.0 1.0 CE2 C:TYR405 4.1 115.1 1.0 CAI C:ZK1901 4.1 124.8 1.0 OH C:TYR450 4.3 129.5 1.0 CAL C:ZK1901 4.3 177.8 1.0 CG C:GLU402 4.3 171.3 1.0 CAK C:ZK1901 4.5 158.9 1.0 OE2 C:GLU402 4.5 216.6 1.0 CD2 C:TYR405 4.7 121.6 1.0 SD C:MET708 4.7 179.6 1.0 CAV C:ZK1901 4.7 116.2 1.0 OH C:TYR732 4.8 82.3 1.0 CB C:GLU402 4.8 155.1 1.0 CG C:MET708 4.9 137.6 1.0 CB C:MET708 4.9 152.6 1.0 CAW C:ZK1901 5.0 111.8 1.0

Fluorine binding site 10 out of 12 in the Resting State Homomeric GLUA2 F231A Mutant Ampa Receptor in Complex with Tarp Gamma-2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 10 of Resting State Homomeric GLUA2 F231A Mutant Ampa Receptor in Complex with Tarp Gamma-2 within 5.0Å range: probe atom residue distance (Å) B Occ D:F901 b:112.9 occ:1.00 FAF D:ZK1901 0.0 112.9 1.0 CAZ D:ZK1901 1.3 120.5 1.0 FAH D:ZK1901 2.1 136.7 1.0 FAG D:ZK1901 2.1 150.1 1.0 CAS D:ZK1901 2.3 104.8 1.0 CAJ D:ZK1901 2.7 97.7 1.0 CE2 D:TYR405 3.4 151.4 1.0 CAR D:ZK1901 3.6 124.6 1.0 CG D:PRO478 3.7 133.1 1.0 CB D:PRO478 3.7 139.1 1.0 CG D:GLU402 3.8 186.2 1.0 OH D:TYR450 3.8 164.5 1.0 OH D:TYR732 3.9 121.7 1.0 CD2 D:TYR405 3.9 164.1 1.0 CAV D:ZK1901 4.1 122.6 1.0 NAX D:ZK1901 4.2 151.4 1.0 CAN D:ZK1901 4.3 167.1 1.0 CE D:MET708 4.3 182.1 1.0 CZ D:TYR405 4.4 145.8 1.0 CZ D:TYR732 4.5 113.0 1.0 CZ D:TYR450 4.5 165.9 1.0 OE2 D:GLU402 4.6 199.5 1.0 CD D:GLU402 4.6 198.4 1.0 CAM D:ZK1901 4.6 166.3 1.0 OH D:TYR405 4.7 177.6 1.0 O D:PRO478 4.7 92.9 1.0 CAL D:ZK1901 4.7 159.5 1.0 CAI D:ZK1901 4.7 119.3 1.0 CB D:GLU402 4.8 188.5 1.0 CAW D:ZK1901 4.9 111.5 1.0 CE1 D:TYR450 5.0 153.5 1.0 NAP D:ZK1901 5.0 111.3 1.0

D.Zhang, J.Ivica, J.M.Krieger, H.Ho, K.Yamashita, O.Cais, I.Greger. Ntd Dynamics Dictate Gating Routes in A Homomeric GLUA1 Ampa Receptor Complex To Be Published.