Fluorine in PDB 8f0w: Tudor Domain of Tumor Suppressor P53BP1 with Mfp-5956

The structure of Tudor Domain of Tumor Suppressor P53BP1 with Mfp-5956, PDB code: 8f0w was solved by J.The, Z.Hong, A.Dong, S.Headey, M.Gunzburg, B.Doak, L.I.James, C.Bountra, C.H.Arrowsmith, A.M.Edwards, P.J.Brown, Structural Genomics Consortium(Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.01 / 1.52
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	48.479, 77.027, 87.208, 90, 90, 90
R / Rfree (%)	21.2 / 23.4

The binding sites of Fluorine atom in the Tudor Domain of Tumor Suppressor P53BP1 with Mfp-5956 (pdb code 8f0w). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Tudor Domain of Tumor Suppressor P53BP1 with Mfp-5956, PDB code: 8f0w:
Jump to Fluorine binding site number: 1; 2;

Fluorine binding site 1 out of 2 in the Tudor Domain of Tumor Suppressor P53BP1 with Mfp-5956


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Tudor Domain of Tumor Suppressor P53BP1 with Mfp-5956 within 5.0Å range: probe atom residue distance (Å) B Occ A:F1701 b:18.4 occ:1.00 F A:X9N1701 0.0 18.4 1.0 C14 A:X9N1701 1.4 20.8 1.0 C15 A:X9N1701 2.3 23.3 1.0 C7 A:X9N1701 2.4 19.7 1.0 N A:X9N1701 2.8 21.5 1.0 ND2 A:ASN1498 2.9 18.7 1.0 C8 A:X9N1701 3.1 20.1 1.0 OH B:TYR1552 3.1 26.9 1.0 C4 B:X9N1701 3.6 22.0 1.0 C4 A:X9N1701 3.6 23.2 1.0 CZ3 A:TRP1495 3.6 15.8 1.0 C6 A:X9N1701 3.6 24.1 1.0 C B:X9N1701 3.7 22.6 1.0 C5 B:X9N1701 3.8 21.2 1.0 OH A:TYR1502 4.0 15.5 1.0 C15 B:X9N1701 4.0 22.7 1.0 O B:X9N1701 4.1 22.8 1.0 C5 A:X9N1701 4.1 22.9 1.0 C9 A:X9N1701 4.1 21.1 1.0 CZ B:TYR1552 4.2 24.6 1.0 CG A:ASN1498 4.2 16.1 1.0 C1 B:X9N1701 4.2 23.4 1.0 C13 A:X9N1701 4.2 19.6 1.0 O B:HOH1805 4.3 28.8 1.0 C6 B:X9N1701 4.4 20.6 1.0 CE3 A:TRP1495 4.4 15.1 1.0 CH2 A:TRP1495 4.5 15.8 1.0 CE1 B:TYR1552 4.5 23.6 1.0 C14 B:X9N1701 4.6 21.4 1.0 C7 B:X9N1701 4.8 20.2 1.0 OD1 A:ASN1498 4.9 17.6 1.0 C A:X9N1701 4.9 27.6 1.0 CZ A:TYR1502 4.9 14.7 1.0 CE2 B:PHE1553 5.0 21.4 1.0

Fluorine binding site 2 out of 2 in the Tudor Domain of Tumor Suppressor P53BP1 with Mfp-5956


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Tudor Domain of Tumor Suppressor P53BP1 with Mfp-5956 within 5.0Å range: probe atom residue distance (Å) B Occ B:F1701 b:22.5 occ:1.00 F B:X9N1701 0.0 22.5 1.0 C14 B:X9N1701 1.4 21.4 1.0 C15 B:X9N1701 2.3 22.7 1.0 C7 B:X9N1701 2.4 20.2 1.0 N B:X9N1701 2.7 21.7 1.0 C8 B:X9N1701 3.0 21.8 1.0 ND2 B:ASN1498 3.3 24.0 1.0 C A:X9N1701 3.5 27.6 1.0 CZ3 B:TRP1495 3.6 22.9 1.0 C4 B:X9N1701 3.6 22.0 1.0 C6 B:X9N1701 3.6 20.6 1.0 C4 A:X9N1701 3.6 23.2 1.0 C1 A:X9N1701 3.7 25.9 1.0 C9 B:X9N1701 3.8 21.6 1.0 C15 A:X9N1701 3.9 23.3 1.0 O A:X9N1701 3.9 27.6 1.0 OH B:TYR1502 4.1 20.0 1.0 C5 B:X9N1701 4.1 21.2 1.0 C13 B:X9N1701 4.1 21.8 1.0 UNK B:UNX1703 4.3 30.0 1.0 C5 A:X9N1701 4.3 22.9 1.0 CE3 B:TRP1495 4.4 21.6 1.0 CH2 B:TRP1495 4.5 21.8 1.0 UNK B:UNX1718 4.5 30.0 1.0 CG B:ASN1498 4.6 20.3 1.0 CZ A:PHE1553 4.7 20.4 1.0 C12 B:X9N1701 4.8 21.3 1.0 C B:X9N1701 4.8 22.6 1.0 C14 A:X9N1701 4.8 20.8 1.0 C2 A:X9N1701 4.8 27.9 1.0 N1 B:X9N1701 4.9 20.8 1.0 O B:X9N1701 5.0 22.8 1.0 CZ B:TYR1502 5.0 17.8 1.0

J.The, Z.Hong, A.Dong, S.Headey, M.Gunzburg, B.Doak, L.I.James, C.Bountra, C.H.Arrowsmith, A.M.Edwards, P.J.Brown, Structural Genomics Consortium (Sgc). Tudor Domain of Tumor Suppressor P53BP1 with Mfp-5956 To Be Published.