Fluorine in PDB 8fkf: Crystal Structure of Ppargamma Ligand-Binding Domain in Complex with N-Cor Peptide and Inverse Agonist SR36706

The structure of Crystal Structure of Ppargamma Ligand-Binding Domain in Complex with N-Cor Peptide and Inverse Agonist SR36706, PDB code: 8fkf was solved by B.S.Mactavish, D.J.Kojetin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.15 / 1.82
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	61.765, 61.765, 161.084, 90, 90, 90
R / Rfree (%)	18.1 / 21.6

The binding sites of Fluorine atom in the Crystal Structure of Ppargamma Ligand-Binding Domain in Complex with N-Cor Peptide and Inverse Agonist SR36706 (pdb code 8fkf). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of Ppargamma Ligand-Binding Domain in Complex with N-Cor Peptide and Inverse Agonist SR36706, PDB code: 8fkf:

Fluorine binding site 1 out of 1 in the Crystal Structure of Ppargamma Ligand-Binding Domain in Complex with N-Cor Peptide and Inverse Agonist SR36706


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of Ppargamma Ligand-Binding Domain in Complex with N-Cor Peptide and Inverse Agonist SR36706 within 5.0Å range: probe atom residue distance (Å) B Occ A:F501 b:35.5 occ:1.00 F09 A:Y5X501 0.0 35.5 1.0 C08 A:Y5X501 1.4 30.1 1.0 C10 A:Y5X501 2.4 29.2 1.0 C07 A:Y5X501 2.4 36.3 1.0 N06 A:Y5X501 3.6 45.8 1.0 C04 A:Y5X501 3.6 30.0 1.0 CG A:HIS323 3.7 30.1 1.0 CB A:HIS323 3.7 22.7 1.0 CG1 A:VAL446 3.8 29.7 1.0 ND1 A:HIS323 3.9 29.6 1.0 CE2 A:TYR327 4.0 19.8 1.0 CA A:VAL446 4.0 20.8 1.0 CB A:HIS449 4.1 36.2 1.0 C05 A:Y5X501 4.1 41.9 1.0 OH A:TYR327 4.1 22.7 1.0 CG2 A:VAL446 4.2 25.5 1.0 O A:VAL446 4.2 24.4 1.0 CB A:VAL446 4.2 24.2 1.0 CG A:HIS449 4.3 38.0 1.0 CE2 A:TYR477 4.3 24.9 1.0 CD2 A:HIS323 4.3 29.3 1.0 CZ A:TYR327 4.5 20.0 1.0 CE1 A:HIS323 4.5 30.3 1.0 C A:VAL446 4.6 22.4 1.0 CD2 A:HIS449 4.6 38.8 1.0 NE2 A:HIS323 4.8 31.6 1.0 N03 A:Y5X501 4.8 33.8 1.0 OH A:TYR477 4.9 32.7 1.0 CA A:HIS323 4.9 21.6 1.0 CZ A:TYR477 4.9 32.8 1.0 ND1 A:HIS449 5.0 29.8 1.0 CD2 A:TYR327 5.0 18.1 1.0 CD2 A:TYR477 5.0 21.5 1.0

B.S.Mactavish, D.J.Kojetin. Crystal Structure of Ppargamma Ligand-Binding Domain in Complex with N-Cor Peptide and SR36706 To Be Published.