Fluorine in PDB 8fw5: Chimeric HSGATOR1-Spgtr-Splam Complex

The structure of Chimeric HSGATOR1-Spgtr-Splam Complex also contains other interesting chemical elements:

Aluminium	(Al)	1 atom
Magnesium	(Mg)	1 atom

The binding sites of Fluorine atom in the Chimeric HSGATOR1-Spgtr-Splam Complex (pdb code 8fw5). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Chimeric HSGATOR1-Spgtr-Splam Complex, PDB code: 8fw5:
Jump to Fluorine binding site number: 1; 2; 3;

Fluorine binding site 1 out of 3 in the Chimeric HSGATOR1-Spgtr-Splam Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Chimeric HSGATOR1-Spgtr-Splam Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:F502 b:68.6 occ:1.00 F1 D:AF3502 0.0 68.6 1.0 AL D:AF3502 1.6 59.7 1.0 O2B D:GDP501 2.3 55.7 1.0 O1B D:GDP501 2.5 55.7 1.0 NZ D:LYS15 2.8 41.8 1.0 F2 D:AF3502 2.8 68.4 1.0 F3 D:AF3502 2.8 64.9 1.0 PB D:GDP501 2.9 55.7 1.0 N D:GLY60 3.1 54.5 1.0 CE D:LYS15 3.3 39.2 1.0 CA D:GLY60 3.4 58.3 1.0 N D:GLY12 3.6 57.7 1.0 O D:ARG10 3.6 72.0 1.0 CA D:SER11 3.8 53.2 1.0 O3B D:GDP501 3.8 55.7 1.0 C D:SER11 4.2 61.7 1.0 MG D:MG503 4.2 51.8 1.0 O3A D:GDP501 4.2 55.7 1.0 NE2 D:GLN61 4.3 57.7 1.0 C D:GLY59 4.3 54.1 1.0 C D:GLY60 4.3 57.4 1.0 C D:ARG10 4.4 69.8 1.0 N D:SER11 4.5 57.0 1.0 CA D:GLY12 4.6 58.5 1.0 CA D:GLY59 4.6 48.6 1.0 NH2 B:ARG78 4.7 82.3 1.0 CB D:SER11 4.7 58.6 1.0 O D:CYS58 4.7 65.7 1.0 CD D:LYS15 4.8 38.2 1.0 N D:GLN61 4.8 58.9 1.0 OG D:SER11 4.8 69.3 1.0 OE1 D:GLN61 4.8 65.2 1.0 N D:SER13 4.9 49.8 1.0 CD D:GLN61 4.9 54.2 1.0

Fluorine binding site 2 out of 3 in the Chimeric HSGATOR1-Spgtr-Splam Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Chimeric HSGATOR1-Spgtr-Splam Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:F502 b:68.4 occ:1.00 F2 D:AF3502 0.0 68.4 1.0 O1B D:GDP501 1.4 55.7 1.0 AL D:AF3502 1.6 59.7 1.0 MG D:MG503 2.0 51.8 1.0 PB D:GDP501 2.6 55.7 1.0 F3 D:AF3502 2.8 64.9 1.0 O3B D:GDP501 2.8 55.7 1.0 F1 D:AF3502 2.8 68.6 1.0 OG1 D:THR37 3.1 62.6 1.0 CB D:THR37 3.3 59.2 1.0 N D:THR37 3.3 55.1 1.0 O2B D:GDP501 3.4 55.7 1.0 O3A D:GDP501 3.8 55.7 1.0 O1A D:GDP501 3.9 55.7 1.0 CA D:THR37 3.9 55.3 1.0 OG D:SER16 4.0 59.2 1.0 C D:ALA36 4.4 59.0 1.0 CA D:ALA36 4.5 48.9 1.0 PA D:GDP501 4.5 55.7 1.0 O D:THR37 4.6 61.9 1.0 CG2 D:THR37 4.7 54.6 1.0 O D:GLY35 4.8 59.6 1.0 C D:THR37 4.8 58.2 1.0 CE D:LYS15 4.8 39.2 1.0 N D:GLY60 4.9 54.5 1.0 CB D:SER16 4.9 51.1 1.0 NZ D:LYS15 4.9 41.8 1.0 NH1 B:ARG78 5.0 72.8 1.0

Fluorine binding site 3 out of 3 in the Chimeric HSGATOR1-Spgtr-Splam Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Chimeric HSGATOR1-Spgtr-Splam Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:F502 b:64.9 occ:1.00 F3 D:AF3502 0.0 64.9 1.0 AL D:AF3502 1.6 59.7 1.0 NE2 D:GLN61 2.5 57.7 1.0 O1B D:GDP501 2.7 55.7 1.0 F2 D:AF3502 2.8 68.4 1.0 F1 D:AF3502 2.8 68.6 1.0 OE1 D:GLN61 3.1 65.2 1.0 CD D:GLN61 3.1 54.2 1.0 NH2 B:ARG78 3.3 82.3 1.0 CZ B:ARG78 3.6 77.0 1.0 NE B:ARG78 4.0 76.1 1.0 N D:THR37 4.0 55.1 1.0 PB D:GDP501 4.1 55.7 1.0 CB D:ALA36 4.1 49.1 1.0 OG D:SER11 4.1 69.3 1.0 NH1 B:ARG78 4.1 72.8 1.0 CA D:ALA36 4.3 48.9 1.0 N D:GLY12 4.3 57.7 1.0 N D:GLY60 4.4 54.5 1.0 O2B D:GDP501 4.4 55.7 1.0 O D:THR37 4.5 61.9 1.0 CG D:GLN61 4.6 46.2 1.0 C D:ALA36 4.7 59.0 1.0 CA D:SER11 4.7 53.2 1.0 CB D:SER11 4.8 58.6 1.0 MG D:MG503 4.8 51.8 1.0 O3A D:GDP501 4.9 55.7 1.0 CD B:ARG78 4.9 72.5 1.0 N D:GLN61 4.9 58.9 1.0 CA D:GLY60 4.9 58.3 1.0 CA D:THR37 5.0 55.3 1.0 C D:SER11 5.0 61.7 1.0

S.D.Tettoni, S.B.Egri, D.D.Doxsey, K.Veinotte, C.Ouch, J.Y.Chang, K.Song, C.Xu, K.Shen. Structure of the Schizosaccharomyces Pombe Gtr-Lam Complex Reveals Evolutionary Divergence of MTORC1-Dependent Amino Acid Sensing. Structure 2023.
ISSN: ISSN 0969-2126
PubMed: 37453417
DOI: 10.1016/J.STR.2023.06.012