Fluorine in PDB 8fws: Structure of the Ligand-Binding and Transmembrane Domains of Kainate Receptor GLUK2 in Complex with the Positive Allosteric Modulator BPAM344

Other elements in 8fws:

The structure of Structure of the Ligand-Binding and Transmembrane Domains of Kainate Receptor GLUK2 in Complex with the Positive Allosteric Modulator BPAM344 also contains other interesting chemical elements:

Sodium (Na) 6 atoms
Chlorine (Cl) 2 atoms

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Structure of the Ligand-Binding and Transmembrane Domains of Kainate Receptor GLUK2 in Complex with the Positive Allosteric Modulator BPAM344 (pdb code 8fws). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the Structure of the Ligand-Binding and Transmembrane Domains of Kainate Receptor GLUK2 in Complex with the Positive Allosteric Modulator BPAM344, PDB code: 8fws:
Jump to Fluorine binding site number: 1; 2; 3; 4;

Fluorine binding site 1 out of 4 in 8fws

Go back to Fluorine Binding Sites List in 8fws
Fluorine binding site 1 out of 4 in the Structure of the Ligand-Binding and Transmembrane Domains of Kainate Receptor GLUK2 in Complex with the Positive Allosteric Modulator BPAM344


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Structure of the Ligand-Binding and Transmembrane Domains of Kainate Receptor GLUK2 in Complex with the Positive Allosteric Modulator BPAM344 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F1001

b:7.4
occ:1.00
FAC A:2J91001 0.0 7.4 1.0
CAK A:2J91001 1.4 7.4 1.0
CAD A:2J91001 2.4 7.4 1.0
CAF A:2J91001 2.4 7.4 1.0
CA D:GLY763 3.3 14.9 1.0
CG2 D:THR535 3.3 17.3 1.0
CB D:PRO532 3.5 14.7 1.0
O D:LYS762 3.5 17.2 1.0
O D:MET534 3.5 20.9 1.0
CG D:PRO532 3.6 14.7 1.0
CAE A:2J91001 3.6 7.4 1.0
CAM A:2J91001 3.7 7.4 1.0
CA D:THR535 3.7 17.3 1.0
CB D:THR535 3.8 17.3 1.0
N D:GLY763 3.8 14.9 1.0
C D:LYS762 3.8 17.2 1.0
CAL A:2J91001 4.2 7.4 1.0
C D:MET534 4.3 20.9 1.0
N D:THR535 4.4 17.3 1.0
C D:GLY763 4.5 14.9 1.0
CAD A:2J91009 4.6 33.1 1.0
CAK A:2J91009 4.8 33.1 1.0
C D:THR535 4.9 17.3 1.0
N D:TYR764 4.9 18.2 1.0
FAC A:2J91009 4.9 33.1 1.0
N D:LEU536 5.0 17.2 1.0
CA D:LYS762 5.0 17.2 1.0
CA D:PRO532 5.0 14.7 1.0
CD D:PRO532 5.0 14.7 1.0

Fluorine binding site 2 out of 4 in 8fws

Go back to Fluorine Binding Sites List in 8fws
Fluorine binding site 2 out of 4 in the Structure of the Ligand-Binding and Transmembrane Domains of Kainate Receptor GLUK2 in Complex with the Positive Allosteric Modulator BPAM344


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Structure of the Ligand-Binding and Transmembrane Domains of Kainate Receptor GLUK2 in Complex with the Positive Allosteric Modulator BPAM344 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F1009

b:33.1
occ:1.00
FAC A:2J91009 0.0 33.1 1.0
CAK A:2J91009 1.4 33.1 1.0
CAD A:2J91009 2.4 33.1 1.0
CAF A:2J91009 2.4 33.1 1.0
CA A:GLY763 3.3 45.2 1.0
CG2 A:THR535 3.3 44.4 1.0
O A:LYS762 3.4 53.3 1.0
CB A:PRO532 3.4 41.4 1.0
CG A:PRO532 3.4 41.4 1.0
CAE A:2J91009 3.6 33.1 1.0
CAM A:2J91009 3.7 33.1 1.0
O A:MET534 3.8 44.8 1.0
C A:LYS762 4.0 53.3 1.0
N A:GLY763 4.0 45.2 1.0
CA A:THR535 4.1 44.4 1.0
CB A:THR535 4.1 44.4 1.0
CAL A:2J91009 4.2 33.1 1.0
C A:GLY763 4.5 45.2 1.0
CAD A:2J91001 4.5 7.4 1.0
C A:MET534 4.5 44.8 1.0
N A:THR535 4.6 44.4 1.0
CAK A:2J91001 4.7 7.4 1.0
CD A:PRO532 4.8 41.4 1.0
CAE A:2J91001 4.8 7.4 1.0
CA A:PRO532 4.9 41.4 1.0
FAC A:2J91001 4.9 7.4 1.0
N A:TYR764 4.9 48.2 1.0

Fluorine binding site 3 out of 4 in 8fws

Go back to Fluorine Binding Sites List in 8fws
Fluorine binding site 3 out of 4 in the Structure of the Ligand-Binding and Transmembrane Domains of Kainate Receptor GLUK2 in Complex with the Positive Allosteric Modulator BPAM344


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Structure of the Ligand-Binding and Transmembrane Domains of Kainate Receptor GLUK2 in Complex with the Positive Allosteric Modulator BPAM344 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:F1001

b:15.7
occ:1.00
FAC C:2J91001 0.0 15.7 1.0
CAK C:2J91001 1.4 15.7 1.0
CAF C:2J91001 2.4 15.7 1.0
CAD C:2J91001 2.4 15.7 1.0
CG2 C:THR535 3.3 45.7 1.0
CA C:GLY763 3.4 46.9 1.0
O C:LYS762 3.4 54.9 1.0
CB C:PRO532 3.4 44.2 1.0
CG C:PRO532 3.4 44.2 1.0
CAE C:2J91001 3.6 15.7 1.0
CAM C:2J91001 3.7 15.7 1.0
O C:MET534 3.9 46.3 1.0
C C:LYS762 4.1 54.9 1.0
N C:GLY763 4.1 46.9 1.0
CB C:THR535 4.1 45.7 1.0
CA C:THR535 4.1 45.7 1.0
CAL C:2J91001 4.2 15.7 1.0
CAD C:2J91002 4.5 9.1 1.0
C C:GLY763 4.6 46.9 1.0
C C:MET534 4.6 46.3 1.0
N C:THR535 4.7 45.7 1.0
CAK C:2J91002 4.7 9.1 1.0
CD C:PRO532 4.8 44.2 1.0
CAE C:2J91002 4.9 9.1 1.0
FAC C:2J91002 4.9 9.1 1.0
CA C:PRO532 5.0 44.2 1.0

Fluorine binding site 4 out of 4 in 8fws

Go back to Fluorine Binding Sites List in 8fws
Fluorine binding site 4 out of 4 in the Structure of the Ligand-Binding and Transmembrane Domains of Kainate Receptor GLUK2 in Complex with the Positive Allosteric Modulator BPAM344


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Structure of the Ligand-Binding and Transmembrane Domains of Kainate Receptor GLUK2 in Complex with the Positive Allosteric Modulator BPAM344 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:F1002

b:9.1
occ:1.00
FAC C:2J91002 0.0 9.1 1.0
CAK C:2J91002 1.4 9.1 1.0
CAD C:2J91002 2.4 9.1 1.0
CAF C:2J91002 2.4 9.1 1.0
CA B:GLY763 3.3 14.6 1.0
CG2 B:THR535 3.3 16.8 1.0
O B:LYS762 3.4 16.7 1.0
O B:MET534 3.5 20.1 1.0
CB B:PRO532 3.5 14.0 1.0
CAE C:2J91002 3.6 9.1 1.0
CA B:THR535 3.7 16.8 1.0
CAM C:2J91002 3.7 9.1 1.0
CG B:PRO532 3.7 14.0 1.0
N B:GLY763 3.8 14.6 1.0
CB B:THR535 3.8 16.8 1.0
C B:LYS762 3.8 16.7 1.0
CAL C:2J91002 4.2 9.1 1.0
C B:MET534 4.2 20.1 1.0
N B:THR535 4.3 16.8 1.0
C B:GLY763 4.5 14.6 1.0
CAD C:2J91001 4.6 15.7 1.0
CAK C:2J91001 4.8 15.7 1.0
C B:THR535 4.8 16.8 1.0
N B:LEU536 4.9 16.9 1.0
CA B:LYS762 4.9 16.7 1.0
N B:TYR764 4.9 18.4 1.0
FAC C:2J91001 4.9 15.7 1.0

Reference:

S.P.Gangwar, L.Y.Yen, M.V.Yelshanskaya, A.I.Sobolevsky. Positive and Negative Allosteric Modulation of GLUK2 Kainate Receptors By BPAM344 and Antiepileptic Perampanel. Cell Rep V. 42 12124 2023.
ISSN: ESSN 2211-1247
PubMed: 36857176
DOI: 10.1016/J.CELREP.2023.112124
Page generated: Tue Apr 25 20:18:21 2023

Last articles

Ca in 3OOR
Ca in 3OOY
Ca in 3ONR
Ca in 3OM7
Ca in 3OM6
Ca in 3OMJ
Ca in 3OM4
Ca in 3OMN
Ca in 3OMA
Ca in 3OJY
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy