Fluorine in PDB 8fye: 4-F, 5-Meo-Pyrt-Bound Serotonin 1A (5-HT1A) Receptor-GI1 Protein Complex

The binding sites of Fluorine atom in the 4-F, 5-Meo-Pyrt-Bound Serotonin 1A (5-HT1A) Receptor-GI1 Protein Complex (pdb code 8fye). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the 4-F, 5-Meo-Pyrt-Bound Serotonin 1A (5-HT1A) Receptor-GI1 Protein Complex, PDB code: 8fye:

Fluorine binding site 1 out of 1 in the 4-F, 5-Meo-Pyrt-Bound Serotonin 1A (5-HT1A) Receptor-GI1 Protein Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of 4-F, 5-Meo-Pyrt-Bound Serotonin 1A (5-HT1A) Receptor-GI1 Protein Complex within 5.0Å range: probe atom residue distance (Å) B Occ R:F501 b:43.4 occ:1.00 F1 R:YGH501 0.0 43.4 1.0 C3 R:YGH501 1.4 43.4 1.0 C2 R:YGH501 2.4 43.4 1.0 C4 R:YGH501 2.4 43.4 1.0 O7 R:YGH501 2.8 43.4 1.0 CZ R:PHE361 2.9 42.3 1.0 C10 R:YGH501 3.1 43.4 1.0 C11 R:YGH501 3.3 43.4 1.0 CE2 R:PHE361 3.4 42.3 1.0 C5 R:YGH501 3.6 43.4 1.0 C1 R:YGH501 3.7 43.4 1.0 C16 R:YGH501 3.9 43.4 1.0 C12 R:YGH501 4.0 43.4 1.0 CD1 R:ILE189 4.1 61.2 1.0 C8 R:YGH501 4.1 43.4 1.0 CE1 R:PHE361 4.1 42.3 1.0 C6 R:YGH501 4.1 43.4 1.0 C9 R:YGH501 4.4 43.4 1.0 N13 R:YGH501 4.6 43.4 1.0 N1 R:YGH501 4.7 43.4 1.0 CG2 R:ILE189 4.7 61.2 1.0 CD2 R:PHE361 4.8 42.3 1.0 CB R:ALA365 4.9 47.8 1.0 CG2 R:VAL117 5.0 45.1 1.0

A.L.Warren, D.Lankri, M.J.Cunningham, I.C.Serrano, L.F.Parise, A.C.Kruegel, P.Duggan, G.Zilberg, M.J.Capper, V.Havel, S.J.Russo, D.Sames, D.Wacker. Structural Pharmacology and Therapeutic Potential of 5-Methoxytryptamines Nature 2024.
ISSN: ESSN 1476-4687
DOI: 10.1038/S41586-024-07403-2